*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : CD2635000
CHEMICAL NAME : Antipyrine, 4-(dimethylamino)- mixed with sodium
nitrite (1:1)
LAST UPDATED : 199410
DATA ITEMS CITED : 7
MOLECULAR FORMULA : C13-H17-N3-O.N-Na-O2
MOLECULAR WEIGHT : 300.33
WISWESSER LINE NOTATION : T5NNVJ A1 BR& DN1&1 E1 &.NA..N-O2
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
SYNONYMS/TRADE NAMES :
* Aminophenazone mixed with sodium nitrite (1:1)
* Aminopyrine mixed with sodium nitrite (1:1)
* 4-(Dimethylamino)antipyrine mixed with sodium nitrte (1:1)
* Sodium nitrite mixed with aminopyrine (1:1)
* Sodium nitrite mixed with 4-(dimethylamino)antipyrine (1:1)
*** HEALTH HAZARD DATA ***
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 3438 mg/kg/50W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Liver - tumors
REFERENCE :
NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736)
V.1- 1869- Volume(issue)/page/year: 244,176,1973
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 10 gm/kg/40W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Liver - tumors
REFERENCE :
IARCCD IARC Scientific Publications. (Geneva, Switzerland) No.1-26,
1971-78. For publisher information, see IAPUDO. Volume(issue)/page/year:
14,461,1976
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 8000 mg/kg/40W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Liver - tumors
REFERENCE :
IARCCD IARC Scientific Publications. (Geneva, Switzerland) No.1-26,
1971-78. For publisher information, see IAPUDO. Volume(issue)/page/year:
14,461,1976
** MUTATION DATA **
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 1 mg/plate
REFERENCE :
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 12,281,1982
TYPE OF TEST : Cytogenetic analysis
ROUTE OF EXPOSURE : Oral
TEST SYSTEM : Rodent - rat
DOSE/DURATION : 600 mg/kg
REFERENCE :
MFEPDX Methods and Findings in Experimental and Clinical Pharmacology. (J.R.
Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1979-
Volume(issue)/page/year: 1,225,1979
TYPE OF TEST : Host-mediated assay
TEST SYSTEM : Rodent - mouse Bacteria - Salmonella typhimurium
DOSE/DURATION : 200 umol/kg
REFERENCE :
ATSUDG Archives of Toxicology, Supplement. (Springer-Verlag New York, Inc.,
Service Center, 44 Hartz Way, Secaucus, NJ 07094) No.1- 1978-
Volume(issue)/page/year: 4,49,1980
TYPE OF TEST : Host-mediated assay
TEST SYSTEM : Rodent - mouse Bacteria - Escherichia coli
DOSE/DURATION : 10 mg/kg
REFERENCE :
CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland
Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year:
35,199,1981
*** END OF RECORD ***
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| ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| | NAME | CAS |
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Antineoplaston A5
| 142191-84-2 |
|
Antineoplaston AS2-1
| 104624-98-8 |
|
Antineoplaston AS2-5
| 104771-87-1 |
|
Antibiotic SF 1306A
| 52934-70-0 |
|
Antiogoside
| 3981-17-7 |
|
Antioside
| 3981-16-6 |
|
Antioxidant G-15
| 3981-16-6 |
|
Antioxidant G-16
| 61373-87-3 |
|
Antioxidant KSM
| 52622-55-6 |
|
Antioxidant TSP
| 12789-66-1 |
|
Antiphlei factor-ISUBSTANCE DEFINITION :Isolated from Streptomyces aureusREFERENCE :85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., BocaRaton, FL, CRC Press, 1980- Volume(issue)/page/year: 1,407,1980
| 12789-66-1 |
|
Antipyrine
| 60-80-0 |
|
Antipyrine, 4-(beta-acetylstyryl)-
| 24428-81-7 |
|
Antipyrine, 4-allyl-
| 24428-81-7 |
|
Antibiotic SF-1670-A
| 60440-43-9 |
|
Antipyrine, 4-amino-
| 83-07-8 |
|
Antipyrine, 4-(2-(p-aminobenzoyl)ethyl)-
| 24428-98-6 |
|
Antipyrine, 4-amino-, and sodium nitrite
| 24428-98-6 |
|
Antipyrine, 4-(2-(p-anisoyl)vinyl)-
| 24428-77-1 |
|
Antipyrine, 4,4'-azodi-
| 102585-65-9 |
|
Antipyrine, 4-(2-benzoylpropenyl)-
| 24428-80-6 |
|
Antipyrine, 4-(2-benzoylvinyl)-
| 15183-03-6 |
|
Antipyrine, 4-butyl-
| 101496-03-1 |
|
Antipyrine, 4-sec-butyl-
| 96974-48-0 |
|
Antipyrine, compd. with chloral hydrate (12)
| 480-30-8 |
|
Antibiotic SF 2107 A(sub 1)
| 81030-78-6 |
|
Antipyrine, 4-(2-(p-chlorobenzoyl)vinyl)-
| 24429-12-7 |
|
Antipyrine, 4-((p-chlorophenacylidene)amino)-
| 24377-61-5 |
|
Antipyrine, 4-(2-(diethylamino)ethyl)-
| 24377-61-5 |
|
Antipyrine,4-((3,4-dimethoxy-2-(1-pyrrolidinylcarbonyl)benzylidene)amino)-
| 66913-52-8 |
|
Antipyrine, 4-(dimethylamino)-
| 58-15-1 |
|
Antipyrine, 4-(dimethylamino)- mixed with sodiumnitrite (1:1)
| 58-15-1 |
|
Antipyrine, 4-(dimethylamino)-, sodium salt
| 6062-19-7 |
|
Antipyrine, 4-(2,6-dimethylpiperidinothiocarbamoyl)-
| 73791-34-1 |
|
Antipyrine, 4-ethyl-
| 73791-34-1 |
|
Antipyrine, 4-(ethylamino)-
| 15166-10-6 |
|
Antibiotic SF 1306B
| 52934-72-2 |
|
Antipyrine, 4-(2-(p-hydroxybenzoyl)propenyl)-,hydrate
| 26405-20-9 |
|
Antipyrine, 4-isobutyl-
| 26405-20-9 |
|
Antipyrine, 4-isopentyl-
| 26405-20-9 |
|
Antipyrine, 4-isopropyl-
| 479-92-5 |
|
Antipyrine, 4-(isopropylamino)-
| 3615-24-5 |
|
Antipyrine, 4-((m-methoxybenzylidene)amino)-
| 70318-54-6 |
|
Antipyrine, 4-((p-methoxybenzylidene)amino)-
| 32061-14-6 |
|
Antipyrine, 4-((p-methoxyphenacylidene)amino)-
| 24428-97-5 |
|
Antipyrine, 4-(methylamino)-
| 519-98-2 |
|
Antipyrine, 4-((p-methylphenacylidene)amino)-
| 24428-96-4 |
|
Antibiotic SF 1771B
| 63798-93-6 |
|
Antipyrine,4-(4-(3-methyl-2-phenylmorpholino)methyl)-, gentisate
| 63798-93-6 |
|
Antipyrine,4-(4-(3-methyl-2-phenylmorpholino)methyl)-,hydrochloride
| 50321-35-2 |
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