*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : ZE5600000
CHEMICAL NAME : 2,4-Xylenol
CAS REGISTRY NUMBER : 105-67-9
BEILSTEIN REFERENCE NO. : 0636244
REFERENCE : 4-06-00-03126 (Beilstein Handbook Reference)
LAST UPDATED : 199710
DATA ITEMS CITED : 15
MOLECULAR FORMULA : C8-H10-O
MOLECULAR WEIGHT : 122.18
WISWESSER LINE NOTATION : QR B1 D1
COMPOUND DESCRIPTOR : Agricultural Chemical
Tumorigen
Drug
SYNONYMS/TRADE NAMES :
* 2,4-Dimethylphenol
* 4,6-Dimethylphenol
* 1-Hydroxy-2,4-dimethylbenzene
* Phenol, 2,4-dimethyl-
* RCRA waste number U101
* m-Xylenol
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 3200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year: 18(2),58,1974
TYPE OF TEST : LC - Lethal concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : >30 mg/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year: 23(10),52,1979
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1040 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year: 18(2),58,1974
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 809 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year: 18(2),58,1974
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 183 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
20037) V.6- 1963- Volume(issue)/page/year: 18,868,1975
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 100 mg/kg
TOXIC EFFECTS :
Behavioral - sleep
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
20037) V.6- 1963- Volume(issue)/page/year: 23,1350,1980
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 6 gm/kg/10D-I
TOXIC EFFECTS :
Liver - changes in liver weight
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
Blood - changes in leukocyte (WBC) count
REFERENCE :
DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New
York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 16,351,1993
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 48600 mg/kg/90D-I
TOXIC EFFECTS :
Liver - changes in liver weight
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New
York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 16,351,1993
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 16 gm/kg/39W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Skin and Appendages - tumors
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
19,413,1959
*** U.S. STANDARDS AND REGULATIONS ***
EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of
Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year:
54,7740,1989
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X2332
No. of Facilities: 736 (estimated)
No. of Industries: 7
No. of Occupations: 8
No. of Employees: 12254 (estimated)
No. of Female Employees: 786 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
Xylene, tetranitro-
| 24239-79-0 |
Xylenol
| 1300-71-6 |
2,3-Xylenol
| 526-75-0 |
2,4-Xylenol
| 105-67-9 |
2,5-Xylenol
| 95-87-4 |
Venom, spider, Latrodectus variolus
| 95-87-4 |
2,6-Xylenol
| 576-26-1 |
3,4-Xylenol
| 95-65-8 |
3,5-Xylenol
| 108-68-9 |
4,5-Xylenol, 2-amino-
| 6623-41-2 |
3,5-Xylenol, 4-amino-
| 3096-70-6 |
2,6-Xylenol, alpha(sup 2),alpha(sup6)-bis(diethylamino)-4-(4-quinolinylamino)-
| 3096-70-6 |
2,6-Xylenol, 4-bromo-
| 2374-05-2 |
2,4-Xylenol, 6-tert-butyl-
| 1879-09-0 |
3,4-Xylenol, 6-tert-butyl-
| 1445-23-4 |
2,4-Xylenol, 6,6'-butylidenebis-
| 3772-23-4 |
Venom, spider, Loxosceles gaucho
| 3772-23-4 |
3,5-Xylenol, 4-chloro-
| 88-04-0 |
2,4-Xylenol, 6-chloro-alpha(sup 4)-(dimethylamino)-
| 82965-44-4 |
2,6-Xylenol, 4-chloro-alpha(sup 2),alpha(sup2)-di(3,4-xylyl)-
| 64038-53-5 |
2,6-Xylenol, 4-chloro-alpha(sup 2)-(methylimino)-
| 63238-79-9 |
2,6-Xylenol,4-((7-chloro-4-quinolyl)amino)-alpha,alpha'-di-1-pyrrolidinyl-
| 5201-88-7 |
3,4-Xylenol, 6-cyclohexyl-alpha(sup 4)-piperidino-
| 106609-32-9 |
3,5-Xylenol, 4-(dimethylamino)-
| 6120-10-1 |
2,4-Xylenol, alpha-(dimethylamino)-, hydrochloride
| 6120-10-1 |
2,5-Xylenol, alpha-(dimethylamino)-, hydrochloride
| 6120-10-1 |
2,6-Xylenol, alpha-(dimethylamino)-, hydrochloride
| 1198-86-3 |
Venom, spider, Loxosceles reclusa
| 1198-86-3 |
2,4-Xylenol, alpha(sup 4)-(dimethylamino)-6-propyl-,hydrochloride
| 96432-75-6 |
2,6-Xylenol,alpha-((3-(dimethylamino)propyl)methylamino)-4-iodo-,dihydrochloride
| 96432-75-6 |
2,5-Xylenol, 4,6-dinitro-
| 15968-56-6 |
2,6-Xylenol, alpha(sup 2),alpha(sup6)-dipiperidino-4-(4-quinolinylamino)-
| 15968-56-6 |
2,3-Xylenol, 6-isopropyl-alpha(sup 2)-morpholino-
| 1715-74-8 |
2,6-Xylenol, 4-nitro-
| 2423-71-4 |
Xylenol, phosphate (31)
| 25155-23-1 |
Xylia xylocarpa (roxb.) Taub., fruit extractSUBSTANCE DEFINITION :Plant belonging to the family MimosaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 25155-23-1 |
Xylia xylocarpa (roxb.) Taub., stem bark extractSUBSTANCE DEFINITION :Plant belonging to the family FabaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 25155-23-1 |
Xylidine
| 1300-73-8 |
Venom, spider, Loxosceles rufipes
| 1300-73-8 |
2,3-Xylidine
| 87-59-2 |
2,4-Xylidine
| 95-68-1 |
2,5-Xylidine
| 95-78-3 |
2,6-Xylidine
| 87-62-7 |
3,4-Xylidine
| 95-64-7 |
3,5-Xylidine
| 108-69-0 |
2,4-Xylidine, alpha(sup 4)-(p-aminophenyl)-alpha(sup4)-(4-imino-2,5-cyclohexadien- 1-ylidene)-
| 3248-93-9 |
3,4-Xylidine, 6-(beta-carboxypropionyl)-,hydrochloride, hydrate
| 91641-63-3 |
2,6-Xylidine, N-(2-(diethylamino)ethyl)-,dihydrochloride
| 78280-29-2 |
2,6-Xylidine, N,N-dimethyl-4-(phenylazo)-
| 20557-73-7 |
Venom, snake, Trimeresurus flavoviridis, hemorrhagicprinciple 1
| 20557-73-7 |
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