RTECS NUMBER : CO1747600
CHEMICAL NAME : 3-Azoniabicyclo(3.2.1)octane,
1,3,8,8-tetramethyl-3-(3-(trimethylammonio)propyl)-,
dichloride
LAST UPDATED : 199604
DATA ITEMS CITED : 2
MOLECULAR FORMULA : C17-H36-N2.2Cl
MOLECULAR WEIGHT : 339.45
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* N-Dimethylaminopropyl-1-methyl-8,8-dimethyl-3-azobicyclo(3.2.1)octane
dimethochloride
* 1,3,8,8-Tetramethyl-3-(3-(trimethylammonio)propyl)-3-azoniabicyclo(3.2.1
)octane dichloride
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 138 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 47,263,1958
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 20 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
Behavioral - muscle weakness
Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 47,263,1958
*** END OF RECORD ***
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