*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : AG8050000
CHEMICAL NAME : Acetic acid, (2,4-dichlorophenoxy)-, butyl ester
CAS REGISTRY NUMBER : 94-80-4
BEILSTEIN REFERENCE NO. : 2056085
REFERENCE : 3-06-00-00706 (Beilstein Handbook Reference)
LAST UPDATED : 199710
DATA ITEMS CITED : 21
MOLECULAR FORMULA : C12-H14-Cl2-O3
MOLECULAR WEIGHT : 277.16
WISWESSER LINE NOTATION : GR CG DO1VO4
COMPOUND DESCRIPTOR : Agricultural Chemical
Tumorigen
Reproductive Effector
SYNONYMS/TRADE NAMES :
* Butyl 2,4-D
* Butyl (2,4-dichlorophenoxy)acetate
* Butyl ester 2,4-D
* n-Butylester kyseliny 2,4-dichlorfenoxyoctove
* 2,4-D butyl ester
* (2,4-Dichlorophenoxy)acetic acid, butyl ester
* Esso herbicide 10
* Fernesta
* Lironox
* Shell 40
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year:
9,423,1987
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 920 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA.
(Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year:
31(7-9),383,1966
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 425 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
GKNT, 1982 Volume(issue)/page/year: -,29,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 380 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA.
(Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year:
31(7-9),383,1966
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : 780 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
GKNT, 1982 Volume(issue)/page/year: -,29,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : >2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year:
9,423,1987
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 196 mg/kg/28W-I
TOXIC EFFECTS :
Liver - fatty liver degeneration
Liver - other changes
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year: 30(7),48,1986
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 600 mg/kg/4D-I
TOXIC EFFECTS :
Behavioral - ataxia
REFERENCE :
NETEEC Neurotoxicology and Teratology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.9- 1987- Volume(issue)/page/year:
10,81,1988
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 1500 mg/kg
SEX/DURATION : female 6-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
22,14,1972
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 100 ug/kg
SEX/DURATION : female 10 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 44(4),70,1979
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE : 1109 mg/kg
SEX/DURATION : female 12-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
Reproductive - Specific Developmental Abnormalities - craniofacial
(including nose and tongue)
REFERENCE :
AECTCV Archives of Environmental Contamination and Toxicology.
(Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
070944) V.1- 1973- Volume(issue)/page/year: 6,33,1977
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE : 251 mg/kg
SEX/DURATION : female 11 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - immune and
reticuloendothelial system
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan
R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968-
Volume(issue)/page/year: 33,15,1986
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE : 900 mg/kg
SEX/DURATION : female 6-14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - extra-embryonic structures
(e.g., placenta, umbilical cord)
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
Reproductive - Specific Developmental Abnormalities - eye/ear
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: PB223-160
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE : 900 mg/kg
SEX/DURATION : female 6-14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - craniofacial
(including nose and tongue)
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: PB223-160
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE : 414 mg/kg
SEX/DURATION : female 6-14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
number of implants per female; total number of implants per corpora lutea)
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: PB223-160
*** REVIEWS ***
IARC Cancer Review:Animal Inadequate Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 15,111,1977
*** U.S. STANDARDS AND REGULATIONS ***
EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of
Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year:
54,7740,1989
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-RUSSIA:STEL 0.5 mg/m3 JAN 1993
OEL-SWITZERLAND:TWA 10 mg/m3;STEL 50 mg/m3 JAN 1993
OEL-UNITED KINGDOM:TWA 10 mg/m3;STEL 20 mg/m3 JAN 1993
*** STATUS IN U.S. ***
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***
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| ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| | NAME | CAS |
|
Acetic acid,6,7-dichloro-2-methyl-1-oxo-5-indanyloxy-
| 27366-35-4 |
|
Acetic acid,(2,3-dichloro-4-(5-methyl-2-thenoyl)phenoxy)-
| 55901-70-7 |
|
Acetic acid,(o-(2,4-dichloro-1-naphthylamino)phenyl)-, sodiumsalt
| 62809-33-0 |
|
Acetic acid, (2,4-dichloro-6-nitrophenyl) ester
| 37169-10-1 |
|
Acetic acid, (2,3-dichloro-4-(1-oxobutyl)phenoxy)-
| 1217-67-0 |
|
Acetic acid, 2-(N,N-bis(2-chloroethyl)aminophenyl)-,butyl ester
| 66232-25-5 |
|
Acetic acid,2,2'-((3,6-dichloro-9-oxo-9H-fluorene-2,7-diyl)bis(oxy))bis-, dipropyl ester
| 123278-17-1 |
|
Acetic acid, (2,4-dichlorophenoxy)-
| 94-75-7 |
|
Acetic acid, (3,4-dichlorophenoxy)-
| 588-22-7 |
|
Acetic acid, (2,4-dichlorophenoxy)-, compd. with2-aminoethanol (1:1)
| 3599-58-4 |
|
Acetic acid, (2,4-dichlorophenoxy)-, compd. with1-amino-2-propanol (1:1)
| 6365-72-6 |
|
Acetic acid, (2,4-dichlorophenoxy)-, ammonium salt
| 2307-55-3 |
|
Acetic acid, 2,4-dichlorophenoxy-, 2-butenyl ester
| 14600-07-8 |
|
Acetic acid, (2,4-dichlorophenoxy)-,3-(2-butoxyethoxy)propyl ester
| 1928-57-0 |
|
Acetic acid, (2,4-dichlorophenoxy)-, butoxyethylester
| 1929-73-3 |
|
Acetic acid, (2,4-dichlorophenoxy)-,2-butoxy-2-oxoethyl ester
| 52671-26-8 |
|
Acetic acid, (4-(bis(2-chloroethyl)amino)phenyl)-,cholesteryl ester
| 3546-10-9 |
|
Acetic acid, 2,4-dichlorophenoxy-, 3-butoxypropylester
| 1928-45-6 |
|
Acetic acid, dichlorophenoxy-, butyl ester
| 64047-35-4 |
|
Acetic acid, (2,4-dichlorophenoxy)-, butyl ester
| 94-80-4 |
|
Acetic acid, 2,4-dichlorophenoxy-, butyl ester and2,4,5-trichlorophenoxyacetic acid (45.5%: 48.2%)
| 39277-47-9 |
|
Acetic acid, 2,4-dichlorophenoxy-, 4-chloro-2-butenylester
| 2971-38-2 |
|
Acetic acid, (2,4-dichlorophenoxy)-, diethanolaminesalt
| 5742-19-8 |
|
Acetic acid, (2,4-dichlorophenoxy)-, diethylaminesalt
| 20940-37-8 |
|
Acetic acid, (2,4-dichlorophenoxy)-, compd. withN,N-diethylethanamine (1:1)
| 2646-78-8 |
|
Acetic acid, (2,4-dichlorophenoxy)-, compd. withdimethylamine (1:1)
| 2008-39-1 |
|
Acetic acid, 2,4-dichlorophenoxy-,2-dimethylaminoethyl ester, hydrochloride
| 64046-52-2 |
|
Acetic acid, 2-(N,N-bis(2-chloroethyl)aminophenyl)-,decyl ester
| 66276-87-7 |
|
Acetic acid, (2,4-dichlorophenoxy)-, compd. with(Z,Z)-N,N-dimethyl-9,12-octadecadien- 1-amine (1:1),mixt. with (Z)-N,N-dimethyl-9-octadecen-1-amine (2,4-dichlorophenoxy)acetate
| 55256-32-1 |
|
Acetic acid, (2,4-dichlorophenoxy)-, compd. with(Z)-N,N-dimethyl-9-octadecen-1- amine (1:1)
| 53535-36-7 |
|
Acetic acid, (2,4-dichlorophenoxy)-, compd. with1-dodecanamine (1:1)
| 2212-54-6 |
|
Acetic acid, (2,4-dichlorophenoxy)-, ethyl ester
| 533-23-3 |
|
Acetic acid, (2,4-dichlorophenoxy)-, 2-ethylhexylester
| 1928-43-4 |
|
Acetic acid, (2,4-dichlorophenoxy)-, mixt. withN-ethyl-N'-(1-methylethyl)-6-(methylthio)-1,3,5-triazine-2,4-diamine
| 8073-61-8 |
|
Acetic acid, (2,4-dichlorophenoxy)-,2-ethyl-4-methylpentyl ester
| 53404-37-8 |
|
Acetic acid, (2,4-dichlorophenoxy)-, isobutyl ester
| 1713-15-1 |
|
Acetic acid, (2,4-dichlorophenoxy)-, isooctyl ester
| 25168-26-7 |
|
Acetic acid, (2,4-dichlorophenoxy)-, isooctyl ester,mixed with 2-(2,4-dichlorophenoxy) propionic acid,butoxyethyl ester and dicamba
| 25168-26-7 |
|
Acetic acid, (p-(bis(2-chloroethyl)amino)phenyl)-,10a,12a-dimethyl-2-oxohexahydro-5-alpha-2H-phenanthro(2,1-b)pyran-8-yl ester
| 60696-44-8 |
|
Acetic acid, (2,4-dichlorophenoxy)-, isopropyl ester
| 94-11-1 |
|
Acetic acid, 2,4-dichlorophenoxy-, lithium salt
| 3766-27-6 |
|
Acetic acid, (2,4-dichlorophenoxy)-, methyl ester
| 1928-38-7 |
|
Acetic acid, (2,4-dichlorophenoxy)-, 1-methylheptylester
| 1917-97-1 |
|
Acetic acid, (2,4-dichlorophenoxy)-, compd. withmorpholine (1:1)
| 6365-73-7 |
|
Acetic acid, (2,4-dichlorophenoxy)-,2-(1-naphthalenyl)-4-(4-(phenylmethyl)-1-piperidinyl)butyl ester, hydrochloride
| 119607-21-5 |
|
Acetic acid, (2,4-dichlorophenoxy)-, compd. with1,1',1''-nitrilotris(2-propanol)
| 32341-80-3 |
|
Acetic acid, (2,4-dichlorophenoxy)-, compd. withoctylamine (1:1)
| 2212-53-5 |
|
Acetic acid, 2,4-dichlorophenoxy-, octyl ester
| 1928-44-5 |
|
Acetic acid, (2,4-dichlorophenoxy)-, pentyl ester
| 1917-92-6 |
|
Acetic acid, 2-(N,N-bis(2-chloroethyl)aminophenyl)-,dodecyl ester
| 66232-27-7 |
|
|