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MSDS  : o-Cresol, 4-((3-chloro-7-methoxy-9-acridinyl)amino)-alpha-(diet hylamino)-, dihydrochloride
CAS  : 56911-71-8
SYNONYMS  : * 4-((3-Chloro-7-methoxy-9-acridinyl)amino)-alpha-(diethylamino)-o-cresol dihydrochloride * 4-((6-Chloro-2-methoxy-9-acridyl)amino)-alpha-(diethylamino)-o-cresol dihydrochloride * SN 8617
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : GO7143780
CHEMICAL NAME : o-Cresol,
4-((3-chloro-7-methoxy-9-acridinyl)amino)-alpha-(diet
hylamino)-, dihydrochloride
LAST UPDATED : 199606
DATA ITEMS CITED : 5
MOLECULAR FORMULA : C25-H26-Cl-N3-O2.2Cl-H
MOLECULAR WEIGHT : 508.91
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* 4-((3-Chloro-7-methoxy-9-acridinyl)amino)-alpha-(diethylamino)-o-cresol
dihydrochloride
* 4-((6-Chloro-2-methoxy-9-acridyl)amino)-alpha-(diethylamino)-o-cresol
dihydrochloride
* SN 8617

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2
vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year:
1,373,1946

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 275 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2
vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year:
1,373,1946

** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 2640 mg/kg/22D-I
TOXIC EFFECTS :
Related to Chronic Data - death
REFERENCE :
85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2
vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year:
1,373,1946

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Primate - monkey
DOSE/DURATION : 950 mg/kg/19D-I
TOXIC EFFECTS :
Gastrointestinal - nausea or vomiting
Liver - hepatitis (hepatocellular necrosis), diffuse
Related to Chronic Data - death
REFERENCE :
85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2
vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year:
1,373,1946

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 25 mg/kg/5D-I
TOXIC EFFECTS :
Liver - other changes
Kidney, Ureter, Bladder - other changes
REFERENCE :
85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2
vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year:
1,373,1946

*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
o-Cresol, 4-(p-aminophenylazo)-6-methyl- 21554-20-1
o-Cresol, 4-(2-aminopropyl)-, hydrobromide 21554-20-1
Coagulase 9001-13-2
o-Cresol, 4-(alpha-(2-aminopropyl)-p-hydroxybenzyl)- 13957-35-2
p-Cresol, 2-amino-alpha,alpha,alpha-trifluoro- 454-81-9
p-Cresol, 2-(2H-benzotriazol-2-yl)- 2440-22-4
o-Cresol, alpha,5-bis(dimethylamino)-,methylcarbamate (ester), dihydrochloride 2440-22-4
p-Cresol, 2,6-bis(alpha-methylbenzyl)- 1817-68-1
p-Cresol, 2-(exo-2-bornyl)- 1817-68-1
o-Cresol, 4-bromo- 2362-12-1
p-Cresol, 2-bromo- 6627-55-0
o-Cresol,4-bromo-alpha-(alpha,alpha-dimethylphenethylamino)-6-methoxy-, hydrochloride 68398-10-7
p-Cresol,3-bromo-alpha-(alpha,alpha-dimethylphenethylamino)-6-methoxy-, maleate 68397-84-2
Coagumin 68397-84-2
p-Cresol,3-bromo-5-methoxy-alpha-(alpha-methylphenethylamino)-, maleate 68397-86-4
o-Cresol, 4-bromo-6-methoxy-alpha-(phenethylamino)-,hydrochloride 68398-07-2
p-Cresol, 2-bromo-6-methoxy-alpha-(phenethylamino)-,hydrochloride 68398-03-8
o-Cresol, alpha-(p-bromophenylimino)- 886-34-0
m-Cresol, 6-butyl- 5736-70-9
p-Cresol, 2-tert-butyl- 2409-55-4
m-Cresol, 6-tert-butyl-4-chloro- 30894-16-7
o-Cresol,4-tert-butyl-6-chloro-alpha-(2,4-dichlorophenyl)- 23802-22-4
o-Cresol,4-tert-butyl-6-chloro-alpha-(3,4-dichlorophenyl)- 23843-04-1
o-Cresol, 4-sec-butyl-alpha-(p-chlorophenyl)- 23802-14-4
Coal conversion materials, SRC-II heavy distillate 23802-14-4
o-Cresol, 4-tert-butyl-alpha-(p-chlorophenyl)- 20121-09-9
o-Cresol, 4-tert-butyl-alpha-(2,4-dichlorophenyl)- 23802-18-8
o-Cresol, 4-sec-butyl-alpha-(3,4-dichlorophenyl)- 23802-21-3
o-Cresol, 4-tert-butyl-alpha-(3,4-dichlorophenyl)- 23802-20-2
m-Cresol, 4,4'-butylidenebis(6-tert-butyl- 85-60-9
m-Cresol, 6-tert-butyl-4-nitro- 72373-70-7
m-Cresol, 4-chloro- 59-50-7
o-Cresol, 4-chloro- 1570-64-5
o-Cresol, 6-chloro- 87-64-9
o-Cresol, 4-chloro-6-ethyl- 53346-75-1
Coal-derived complex organic mixtureSUBSTANCE DEFINITION :A high-boiling (288-454 degrees C) complexREFERENCE :FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E.First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year:13,662,1989 53346-75-1
o-Cresol, 4-chloro-6-ethyl-alpha-(methylimino)- 56911-71-8
m-Cresol, chlorohexyl- 56911-71-8
o-Cresol,4-((3-chloro-7-methoxy-9-acridinyl)amino)-alpha-(diethylamino)-, dihydrochloride 56911-71-8
o-Cresol, 4-chloro-alpha-(methylimino)- 49649-27-6
o-Cresol, 6-chloro-4-nitroso- 73791-20-5
o-Cresol, 4-chloro-alpha-phenyl- 120-32-1
o-Cresol,4-((7-chloro-4-quinolyl)amino)-alpha-(diethylamino)- 86-42-0
o-Cresol,4-((7-chloro-4-quinolyl)amino)-alpha-(diethylamino)-,dihydrochloride 69-44-3
o-Cresol,4-((7-chloro-4-quinolyl)amino)-alpha-1-pyrrolidinyl-,dihydrochloride 10350-81-9
o-Cresol, 4-chloro-alpha-(3,4-xylyl)- 6955-53-9
Coal dust 6955-53-9
o-Cresol, 4-cyclohexyl-alpha-(diethylamino)-,hydrochloride 106609-25-0
o-Cresol,4-cyclohexyl-alpha-(3,5-dimethylpiperidino)- 106609-24-9
p-Cresol,alpha-cyclohexylidene-alpha-(p-hydroxyphenyl)- 5189-40-2

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