*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : GU7200000
CHEMICAL NAME : Cyclohexanecarbamic acid, N-ethylthio-, S-ethyl ester
CAS REGISTRY NUMBER : 1134-23-2
OTHER CAS REGISTRY NOS. : 71330-39-7
BEILSTEIN REFERENCE NO. : 2937178
LAST UPDATED : 199701
DATA ITEMS CITED : 16
MOLECULAR FORMULA : C11-H21-N-O-S
MOLECULAR WEIGHT : 215.39
WISWESSER LINE NOTATION : L6TJ AN2&VS2
COMPOUND DESCRIPTOR : Agricultural Chemical
Mutagen
SYNONYMS/TRADE NAMES :
* Carbamic acid, cyclohexylethylthio-, S-ethyl ester
* Carbamothioic acid, cyclohexylethyl-, S-ethyl ester
* Cycloate
* S-Ethyl cyclohexylethylthiocarbamate
* S-Ethyl N-ethyl N-cyclohexylthiolcarbamate
* Etsan
* Eurex
* Hexylthiocarbam
* R 2063
* Ro-Neet
* Ronit
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1678 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year:
7,299,1986
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 90 gm/m3/1H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd,
eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year:
A106,1983
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2467 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year:
7,299,1986
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2325 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EQSSDX Environmental Quality and Safety, Supplement. (Stuttgart, Fed. Rep.
Ger.) V.1-5, 1975-76. Discontinued. Volume(issue)/page/year: 3,618,1975
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1275 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - muscle contraction or spasticity
Behavioral - coma
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 51(10),77,1986
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TGANAK Tsitologiya i Genetika. Cytology and Genetics. For English
translation, see CYGEDX. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1- 1967- Volume(issue)/page/year: 16(1),45,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 50(3),26,1985
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 1600 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - muscle contraction or spasticity
Behavioral - coma
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 51(10),77,1986
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Bird - quail
DOSE/DURATION : >2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport
Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year:
9,195,1991
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Mammal - species unspecified
DOSE/DURATION : 2300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 45(5),29,1980
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 27608 mg/kg/17W-I
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - hemorrhage
Behavioral - somnolence (general depressed activity)
Related to Chronic Data - death
REFERENCE :
VRDEA5 Vrachebnoe Delo. Medical Practice. (V/O Mezhdunarodnaya Kniga,
113095 Moscow, USSR) No.1- 1918- Volume(issue)/page/year: (12),118,1971
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2192 mg/kg/40D-I
TOXIC EFFECTS :
Blood - changes in erythrocyte (RBC) count
Blood - changes in leukocyte (WBC) count
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - true cholinesterase
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 51(10),77,1986
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1820 mg/kg/26W-I
TOXIC EFFECTS :
Blood - pigmented or nucleated red blood cells
Blood - changes in erythrocyte (RBC) count
Blood - changes in leukocyte (WBC) count
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 51(10),77,1986
** MUTATION DATA **
TYPE OF TEST : Cytogenetic analysis
ROUTE OF EXPOSURE : Unreported
TEST SYSTEM : Rodent - mouse
DOSE/DURATION : 200 mg/kg
REFERENCE :
TGANAK Tsitologiya i Genetika. Cytology and Genetics. For English
translation, see CYGEDX. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1- 1967- Volume(issue)/page/year: 16(1),45,1982
*** U.S. STANDARDS AND REGULATIONS ***
EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of
Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year:
54,7740,1989
*** STATUS IN U.S. ***
On EPA IRIS database
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
Cyclohexane, 1,2,3,4,5,6-hexachloro-, alpha-isomer
| 319-84-6 |
Cyclohexane, 1,2,3,4,5,6-hexachloro-, beta-isomer
| 319-85-7 |
Cyclohexane, 1,2,3,4,5,6-hexachloro-, delta-isomer
| 319-86-8 |
Cyclohexane, 1,2,3,4,5,6-hexachloro-, gamma-isomer
| 58-89-9 |
Cyclohexane, 1,2,3,4,5,6-hexachloro-, (mixed isomers)
| 58-89-9 |
Cyclohexane, hexadecafluorodimethyl-
| 26637-68-3 |
Cyclohexanecarbamic acid, 2-(diethylamino)ethylester, monohydrochloride
| 26637-68-3 |
Cyclohexane, 1,2,3,4,5,6-hexakis(2-cyanoethoxy)-
| 3055-84-3 |
Cyclohexanehydracrylic acid, alpha-phenyl-,2-(diethylamino)ethyl ester, hydrochloride
| 7477-25-0 |
Cyclohexanemethanol
| 100-49-2 |
Cyclohexanemethanol,alpha-(1-aminoethyl)-alpha-phenyl-, hydrochloride
| 100-49-2 |
Cyclohexanemethanol, alpha-(p-chlorophenyl)-
| 106165-42-8 |
Cyclohexanemethanol, alpha-(1,2-diaminoethyl)-,dihydrochloride, (+-)-
| 106165-42-8 |
Cyclohexanemethanol,alpha-(4-(diethylamino)-1-butynyl)-alpha-phenyl-,hydrochloride
| 4069-27-6 |
Cyclohexanemethanol,alpha-(1-(diethylamino)ethyl)-alpha-phenyl-,hydrochloride
| 4069-27-6 |
Cyclohexanemethanol,alpha-(2-(diethylamino)ethyl)-alpha-phenyl-,hydrochloride
| 13562-21-5 |
Cyclohexanemethanol,alpha-((diethylamino)phenylmethyl)-alpha-phenyl-,hydrochloride
| 13562-21-5 |
Cyclohexanecarbamic acid, 1,1-diphenyl-2-butynylester
| 20930-10-3 |
Cyclohexanemethanol,alpha-(1-(diethylamino)propyl)-alpha-phenyl-,hydrochloride
| 20930-10-3 |
Cyclohexanemethanol,alpha-(3-(diethylamino)-1-propynyl)-alpha-phenyl-,hydrochloride
| 20930-10-3 |
Cyclohexanemethanol,2-(dimethylamino)-alpha,alpha-diphenyl-,hydrochloride
| 20930-10-3 |
Cyclohexanemethanol,3-(dimethylamino)-alpha,alpha-diphenyl-,hydrochloride
| 20930-10-3 |
Cyclohexanemethanol,alpha-(2-(dimethylamino)ethyl)-alpha-phenyl-
| 24252-48-0 |
1,4-Cyclohexanemethanol, divinyl ester
| 17351-75-6 |
Cyclohexanemethanol, alpha-ethynyl-, acetate
| 16169-86-1 |
Cyclohexanemethanol, alpha-ethynyl-, carbamate
| 41416-61-9 |
Cyclohexanemethanol, alpha-ethynyl-4-phenyl-,carbamate, (E)-
| 41416-60-8 |
Cyclohexanemethanol, alpha-(1-hydrazinoethyl)-,hemisulfate (salt)
| 41416-60-8 |
Cyclohexanecarbamic acid, 1,1-diphenyl-2-propynylester
| 10087-89-5 |
Cyclohexanemethanol,4-hydroxy-alpha-(isopropylaminomethyl)-
| 63980-63-2 |
Cyclohexanemethanol,4-hydroxy-alpha-(methylaminomethyl)-
| 63918-84-3 |
Cyclohexanemethanol, alpha-methyl-
| 1193-81-3 |
Cyclohexanemethanol,alpha-(1-methylaminoethyl)-alpha-phenyl-,hydrochloride, DL-
| 1193-81-3 |
Cyclohexanemethanol, alpha-(methylaminomethyl)-
| 21581-48-6 |
Cyclohexanemethanol,alpha-(1-(1-methylhydrazino)ethyl)-, sulfate (2:1)(salt)
| 21581-48-6 |
Cyclohexanemethanol,alpha-(3-morpholino-1-propynyl)-alpha-phenyl-,hydrochloride
| 21581-48-6 |
Cyclohexanemethanol, 1-phenyl-
| 68692-77-3 |
Cyclohexanemethanol, alpha-phenyl-2-piperidino-,acetate, hydrochloride
| 101564-31-2 |
Cyclohexanemethanol, alpha-phenyl-1-piperidino-,hydrochloride
| 101564-32-3 |
Cyclohexanecarbamic acid, N-ethylthio-, S-ethyl ester
| 1134-23-2 |
Cyclohexanemethanol,alpha-phenyl-alpha-(3-piperidino-1-propynyl)-,hydrochloride
| 2269-28-5 |
Cyclohexanemethanol,alpha-phenyl-alpha-(3-(1-pyrrolidinyl)-1-propynyl)-,hydrochloride
| 2269-28-5 |
Cyclohexanemethanol, alpha-((2-pyridylamino)methyl)-,hydrochloride
| 1020-19-5 |
Cyclohexane, methyl-
| 108-87-2 |
Cyclohexanemethylamine
| 3218-02-8 |
Cyclohexanemethylamine,4-(4-aminophenyl)-alpha-methyl-, oxalate, hydrate(2:2:1), (E)-
| 113524-37-1 |
Cyclohexanemethylamine, alpha-benzyl-N,N-dimethyl-,hydrochloride
| 113524-37-1 |
Cyclohexanemethylamine,4-(4-bromophenyl)-alpha-methyl-, hydrochloride, (E)-
| 113524-38-2 |
Cyclohexanemethylamine,N-(2-chloroethyl)-N-ethyl-1-phenyl-, hydrochloride
| 101564-53-8 |
Cyclohexanemethylamine, 2-chloro-2-(m-methoxyphenyl)-
| 73806-38-9 |
|
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