RTECS NUMBER : KJ8925000
CHEMICAL NAME : Ethanol, 2-butoxy-, acetate
CAS REGISTRY NUMBER : 112-07-2
BEILSTEIN REFERENCE NO. : 1756960
REFERENCE : 4-02-00-00215 (Beilstein Handbook Reference)
LAST UPDATED : 199710
DATA ITEMS CITED : 18
MOLECULAR FORMULA : C8-H16-O3
MOLECULAR WEIGHT : 160.24
WISWESSER LINE NOTATION : 4O2OV1
COMPOUND DESCRIPTOR : Primary Irritant
SYNONYMS/TRADE NAMES :
* Acetic acid, 2-butoxyethyl ester
* 2-Butoxyethanol acetate
* 2-Butoxyethyl acetate
* 2-Butoxyethylester kyseliny octove
* Butyl cellosolve acetate
* Butylcelosolvacetat
* Butylglycol acetate
* Ektasolve EB acetate
* Ethylene glycol monobutyl ether acetate
* Glycol monobutyl ether acetate
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Open irritation test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg
REACTION SEVERITY : Mild
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury
Rd., Danbury, CT 06817) Volume(issue)/page/year: 1/31/1966
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/24H
REACTION SEVERITY : Mild
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,713,1986
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2400 mg/kg
TOXIC EFFECTS :
Kidney, Ureter, Bladder - hematuria
Kidney, Ureter, Bladder - other changes in urine composition
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
51,117,1979
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 3200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650)
Volume(issue)/page/year: 21MAY1971
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 1500 mg/kg
TOXIC EFFECTS :
Kidney, Ureter, Bladder - hematuria
Kidney, Ureter, Bladder - other changes in urine composition
Blood - normocytic anemia
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
51,117,1979
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 5 mL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650)
Volume(issue)/page/year: 21MAY1971
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-AUSTRIA:TWA 20 ppm (135 mg/m3) JAN 1993
OEL-GERMANY:TWA 20 ppm (135 mg/m3);Skin JAN 1993
OEL-THE NETHERLANDS:TWA 20 ppm (135 mg/m3);STEL 40 ppm;Skin JAN 1993
OEL-SWITZERLAND:TWA 20 ppm (135 mg/m3);STEL 40 ppm;Skin JAN 1993
OEL-UNITED KINGDOM:TWA 10 ppm (54 mg/m3);Skin JAN 1993
OEL-UNITED KINGDOM:TWA 5 ppm (24 mg/m3);Skin JAN 1993
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
NIOSH REL TO EGBEA-air:10H TWA 5 ppm (Sk)
REFERENCE :
NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
Health, Education, and Welfare, Reports and Memoranda.
Volume(issue)/page/year: DHHS #92-100,1992
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 81350
No. of Facilities: 4676 (estimated)
No. of Industries: 50
No. of Occupations: 41
No. of Employees: 36527 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 81350
No. of Facilities: 15329 (estimated)
No. of Industries: 116
No. of Occupations: 70
No. of Employees: 150893 (estimated)
No. of Female Employees: 38379 (estimated)