*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : KJ9100000
CHEMICAL NAME : Ethanol, 2-(2-butoxyethoxy)-
CAS REGISTRY NUMBER : 112-34-5
BEILSTEIN REFERENCE NO. : 1739225
REFERENCE : 4-01-00-02394 (Beilstein Handbook Reference)
LAST UPDATED : 199710
DATA ITEMS CITED : 19
MOLECULAR FORMULA : C8-H18-O3
MOLECULAR WEIGHT : 162.26
WISWESSER LINE NOTATION : Q2O2O4
COMPOUND DESCRIPTOR : Primary Irritant
SYNONYMS/TRADE NAMES :
* BUCB
* Butoxydiethylene glycol
* Butoxydiglycol
* 2-(2-Butoxyethoxy)ethanol
* Butyl carbitol
* O-Butyl diethylene glycol
* Butyl dioxitol
* Diethylene glycol n-butyl ether
* Diethylene glycol monobutyl ether
* Diglycol monobutyl ether
* Dowanol DB
* Ektasolve DB
* Glycol ether DB
* Jeffersol DB
* Poly-Solv DB
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 20 mg
REACTION SEVERITY : Severe
REFERENCE :
AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N.
Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918-
Volume(issue)/page/year: 29,1363,1946
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 20 mg/24H
REACTION SEVERITY : Moderate
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,635,1986
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 5660 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DOWCC* Dow Chemical Company Reports. (Dow Chemical USA, Health and
Environment Research, Toxicology Research Lab., Midland, MI 48640)
Volume(issue)/page/year: MSD-41
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 4500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 46(2),14,1981
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert,
Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued.
Volume(issue)/page/year: 12,139,1993
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 850 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
Blood - changes in spleen
REFERENCE :
FEPRA7 Federation Proceedings, Federation of American Societies for
Experimental Biology. (Bethesda, MD) V.1-46, 1942-87.
Volume(issue)/page/year: 6,342,1947
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 6050 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 46(2),14,1981
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 2200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton,
G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82.
Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985.
Volume(issue)/page/year: 2C,3964,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 2700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert,
Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued.
Volume(issue)/page/year: 12,139,1993
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 2 gm/kg
TOXIC EFFECTS :
Behavioral - general anesthetic
Gastrointestinal - other changes
Kidney, Ureter, Bladder - other changes
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA)
V.18-31, 1936-49. For publisher information, see AEHLAU.
Volume(issue)/page/year: 23,259,1941
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 83 gm/kg/13W-I
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain
Related to Chronic Data - death
REFERENCE :
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway,
Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 6,164,1986
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 109 gm/kg/6W-I
TOXIC EFFECTS :
Behavioral - food intake (animal)
Blood - pigmented or nucleated red blood cells
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0570960
TYPE OF TEST : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 5 mg/m3/24H/17W-C
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS
Blood - other changes
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 46(2),14,1981
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 80343
No. of Facilities: 19782 (estimated)
No. of Industries: 151
No. of Occupations: 114
No. of Employees: 246257 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 80343
No. of Facilities: 42981 (estimated)
No. of Industries: 266
No. of Occupations: 158
No. of Employees: 641115 (estimated)
No. of Female Employees: 173797 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***
|
|
|
ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
Ethanol, 2-tert-butoxy-
| 7580-85-0 |
Ethanol, 2-butoxy-, acetate
| 112-07-2 |
Ethanol, 2-(2-butoxyethoxy)-
| 112-34-5 |
Ethanol, 2-(2-butoxyethoxy)-, acetate
| 124-17-4 |
Ethanol, 2-(2-(2-butoxyethoxy)ethoxy)-
| 143-22-6 |
Ethanol, 2-(2-butoxyethoxy)-, phthalate
| 16672-39-2 |
Ethanol, 2,2'-((4-butoxy-3-nitrobenzyl)imino)di-,hydrochloride
| 77905-48-7 |
9,10-Ethanoanthracene,9,10-dihydro-11-(2-(dimethylamino)ethyl)-,hydrochloride
| 14692-49-0 |
Ethanol, 2,2'-((5-butoxy-4-penten-2-ynyl)imino)bis-
| 143337-72-8 |
Ethanol, 2-butoxy-, phosphate (31)
| 78-51-3 |
Ethanol, 2-(6-butoxy-3-pyridylamino)-
| 78-51-3 |
Ethanol, 2-butylamino-
| 111-75-1 |
Ethanol, 2-tert-butylamino-1-(3-chloro-2-thienyl)-
| 62673-45-4 |
Ethanol, 2-tert-butylamino-1-(4-chloro-2-thienyl)-
| 62673-47-6 |
Ethanol, 2-tert-butylamino-1-(3,4-dibromo-2-thienyl)-
| 62673-60-3 |
Ethanol, 2-tert-butylamino-1-(3,5-dibromo-2-thienyl)-
| 62673-59-0 |
Ethanol, 2-tert-butylamino-1-(4,5-dibromo-2-thienyl)-
| 62673-57-8 |
Ethanol,2-tert-butylamino-1-(3,5-dichloro-2-thienyl)-
| 62673-49-8 |
9,10-Ethanoanthracene,9,10-dihydro-11-(2-(dimethylamino)ethyl)-, methiodide
| 14692-50-3 |
Ethanol,2-tert-butylamino-1-(7-ethyl-2-benzofuranyl)-,hydrochloride
| 59652-29-8 |
Ethanol,2-tert-butylamino-1-(5-hydroxy-6-hydroxymethyl-2-pyridyl)-
| 38677-81-5 |
Ethanol, 2-(butylamino)-1-(p-nitrophenyl)-,hydrochloride
| 1892-62-2 |
Ethanol,2-tert-butylamino-1-(3,4,5-tribromo-2-thienyl)-
| 62673-62-5 |
Ethanol,2-tert-butylamino-1-(3,4,5-trichloro-2-thienyl)-
| 62673-51-2 |
Ethanol, 2-((1-butyl-1H-benzimidazol-2-yl)amino)-,monohydrochloride
| 111678-89-8 |
Ethanol,2-(tert-butyl((5-chlorobenzo(b)thien-3-yl)methyl)amino)-, hydrochloride
| 17512-30-0 |
Ethanol,2-(tert-butyl((5-fluorobenzo(b)thien-3-yl)methyl)amino)-, hydrochloride
| 17514-78-2 |
Ethanol, 2,2'-(butylimino)di-
| 102-79-4 |
Ethanol, 2-(butylnitroamino)-, nitrate (ester)
| 82486-82-6 |
9,10-Ethanoanthracene,9,10-dihydro-11-(N-(2-dimethylaminoethyl)-N-methylamino)-, dihydrochloride
| 14692-56-9 |
Ethanol, 2-(butylnitrosamino)-
| 51938-14-8 |
Ethanol, 2-(butylphenoxy)-
| 63980-40-5 |
Ethanol,2-((2-((4-butylphenyl)amino)-6-chloro-9H-purin-9-yl)methoxy)-
| 104715-78-8 |
Ethanol,2-((2-((4-butylphenyl)amino)-6-methoxy-9H-purin-9-yl)methoxy)-, hydrate (2:1)
| 104715-85-7 |
Ethanol,2-((2-((4-butylphenyl)amino)-9H-purin-9-yl)methoxy)-
| 104715-83-5 |
Ethanol, 2-chloro-
| 107-07-3 |
Ethanol, 2-chloro-, acetate
| 542-58-5 |
Ethanol, 2-(N-(6(and7)-chloro-1,4-benzodioxan-2-ylmethyl)-N-methylamino)-
| 101221-50-5 |
Ethanol, 2-((2-chloro-3-benzo(b)thienyl)amino)-,S,S-dioxide
| 39775-24-1 |
Ethanol, 2,2'-((2-chloro-3-benzo(b)thienyl)imino)di-,S,S-dioxide
| 39775-25-2 |
9,10-Ethanoanthracene,9,10-dihydro-11-((N-(2-dimethylaminoethyl)-N-methyl)amino)methyl-, dihydrochloride
| 14692-57-0 |
Ethanol,2-(N-(2-chloro-3-benzo(b)thienyl)methylamino)-,S,S-dioxide
| 62268-33-1 |
Ethanol,2-(N-((5-chlorobenzo(b)thien-3-yl)methyl)-N-ethylamino)-, hydrochloride
| 7349-44-2 |
Ethanol,2-(((5-chlorobenzo(b)thien-3-yl)methyl)isopropylamino)-, hydrochloride
| 16584-14-8 |
Ethanol, 2-(4-(p-chlorobenzyl)phenoxy)-
| 70930-63-1 |
Ethanol, 2-(p-chlorobenzylthio)-
| 71501-40-1 |
Ethanol,2-((6-chloro-5-(2,3-dibromopropyl)-2-methyl-4-pyrimidinyl)amino)-
| 85826-40-0 |
Ethanol,2,2'-((8-chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)imino)bis-, (Z)-2-butenedioate (1:1)
| 34770-84-8 |
Ethanol,2-((5-chloro-2,3-dihydro-1H-inden-2-yl)amino)-
| 34770-84-8 |
Ethanol,2-((5-chloro-2,3-dihydro-1H-inden-2-yl)methylamino)-
| 34770-84-8 |
|
|