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MSDS  : Ethanol, 2-(2-butoxyethoxy)-
CAS  : 112-34-5
SYNONYMS  : * BUCB * Butoxydiethylene glycol * Butoxydiglycol * 2-(2-Butoxyethoxy)ethanol * Butyl carbitol * O-Butyl diethylene glycol * Butyl dioxitol * Diethylene glycol n-butyl ether * Diethylene glycol monobutyl ether * Diglycol monobutyl ether * Dowanol DB * Ektasolve DB * Glycol ether DB * Jeffersol DB * Poly-Solv DB
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : KJ9100000
CHEMICAL NAME : Ethanol, 2-(2-butoxyethoxy)-
CAS REGISTRY NUMBER : 112-34-5
BEILSTEIN REFERENCE NO. : 1739225
REFERENCE : 4-01-00-02394 (Beilstein Handbook Reference)
LAST UPDATED : 199710
DATA ITEMS CITED : 19
MOLECULAR FORMULA : C8-H18-O3
MOLECULAR WEIGHT : 162.26
WISWESSER LINE NOTATION : Q2O2O4
COMPOUND DESCRIPTOR : Primary Irritant
SYNONYMS/TRADE NAMES :
* BUCB
* Butoxydiethylene glycol
* Butoxydiglycol
* 2-(2-Butoxyethoxy)ethanol
* Butyl carbitol
* O-Butyl diethylene glycol
* Butyl dioxitol
* Diethylene glycol n-butyl ether
* Diethylene glycol monobutyl ether
* Diglycol monobutyl ether
* Dowanol DB
* Ektasolve DB
* Glycol ether DB
* Jeffersol DB
* Poly-Solv DB

*** HEALTH HAZARD DATA ***

** SKIN/EYE IRRITATION DATA **

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 20 mg
REACTION SEVERITY : Severe
REFERENCE :
AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N.
Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918-
Volume(issue)/page/year: 29,1363,1946

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 20 mg/24H
REACTION SEVERITY : Moderate
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,635,1986

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 5660 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DOWCC* Dow Chemical Company Reports. (Dow Chemical USA, Health and
Environment Research, Toxicology Research Lab., Midland, MI 48640)
Volume(issue)/page/year: MSD-41

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 4500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 46(2),14,1981

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert,
Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued.
Volume(issue)/page/year: 12,139,1993

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 850 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
Blood - changes in spleen
REFERENCE :
FEPRA7 Federation Proceedings, Federation of American Societies for
Experimental Biology. (Bethesda, MD) V.1-46, 1942-87.
Volume(issue)/page/year: 6,342,1947

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 6050 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 46(2),14,1981

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 2200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton,
G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82.
Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985.
Volume(issue)/page/year: 2C,3964,1982

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 2700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert,
Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued.
Volume(issue)/page/year: 12,139,1993

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 2 gm/kg
TOXIC EFFECTS :
Behavioral - general anesthetic
Gastrointestinal - other changes
Kidney, Ureter, Bladder - other changes
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA)
V.18-31, 1936-49. For publisher information, see AEHLAU.
Volume(issue)/page/year: 23,259,1941

** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 83 gm/kg/13W-I
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain
Related to Chronic Data - death
REFERENCE :
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway,
Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 6,164,1986

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 109 gm/kg/6W-I
TOXIC EFFECTS :
Behavioral - food intake (animal)
Blood - pigmented or nucleated red blood cells
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0570960

TYPE OF TEST : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 5 mg/m3/24H/17W-C
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS
Blood - other changes
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 46(2),14,1981

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 80343
No. of Facilities: 19782 (estimated)
No. of Industries: 151
No. of Occupations: 114
No. of Employees: 246257 (estimated)

NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 80343
No. of Facilities: 42981 (estimated)
No. of Industries: 266
No. of Occupations: 158
No. of Employees: 641115 (estimated)
No. of Female Employees: 173797 (estimated)

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY

EPA TSCA Section 8(d) unpublished health/safety studies

On EPA IRIS database

EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998


*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
Ethanol, 2-tert-butoxy- 7580-85-0
Ethanol, 2-butoxy-, acetate 112-07-2
Ethanol, 2-(2-butoxyethoxy)- 112-34-5
Ethanol, 2-(2-butoxyethoxy)-, acetate 124-17-4
Ethanol, 2-(2-(2-butoxyethoxy)ethoxy)- 143-22-6
Ethanol, 2-(2-butoxyethoxy)-, phthalate 16672-39-2
Ethanol, 2,2'-((4-butoxy-3-nitrobenzyl)imino)di-,hydrochloride 77905-48-7
9,10-Ethanoanthracene,9,10-dihydro-11-(2-(dimethylamino)ethyl)-,hydrochloride 14692-49-0
Ethanol, 2,2'-((5-butoxy-4-penten-2-ynyl)imino)bis- 143337-72-8
Ethanol, 2-butoxy-, phosphate (31) 78-51-3
Ethanol, 2-(6-butoxy-3-pyridylamino)- 78-51-3
Ethanol, 2-butylamino- 111-75-1
Ethanol, 2-tert-butylamino-1-(3-chloro-2-thienyl)- 62673-45-4
Ethanol, 2-tert-butylamino-1-(4-chloro-2-thienyl)- 62673-47-6
Ethanol, 2-tert-butylamino-1-(3,4-dibromo-2-thienyl)- 62673-60-3
Ethanol, 2-tert-butylamino-1-(3,5-dibromo-2-thienyl)- 62673-59-0
Ethanol, 2-tert-butylamino-1-(4,5-dibromo-2-thienyl)- 62673-57-8
Ethanol,2-tert-butylamino-1-(3,5-dichloro-2-thienyl)- 62673-49-8
9,10-Ethanoanthracene,9,10-dihydro-11-(2-(dimethylamino)ethyl)-, methiodide 14692-50-3
Ethanol,2-tert-butylamino-1-(7-ethyl-2-benzofuranyl)-,hydrochloride 59652-29-8
Ethanol,2-tert-butylamino-1-(5-hydroxy-6-hydroxymethyl-2-pyridyl)- 38677-81-5
Ethanol, 2-(butylamino)-1-(p-nitrophenyl)-,hydrochloride 1892-62-2
Ethanol,2-tert-butylamino-1-(3,4,5-tribromo-2-thienyl)- 62673-62-5
Ethanol,2-tert-butylamino-1-(3,4,5-trichloro-2-thienyl)- 62673-51-2
Ethanol, 2-((1-butyl-1H-benzimidazol-2-yl)amino)-,monohydrochloride 111678-89-8
Ethanol,2-(tert-butyl((5-chlorobenzo(b)thien-3-yl)methyl)amino)-, hydrochloride 17512-30-0
Ethanol,2-(tert-butyl((5-fluorobenzo(b)thien-3-yl)methyl)amino)-, hydrochloride 17514-78-2
Ethanol, 2,2'-(butylimino)di- 102-79-4
Ethanol, 2-(butylnitroamino)-, nitrate (ester) 82486-82-6
9,10-Ethanoanthracene,9,10-dihydro-11-(N-(2-dimethylaminoethyl)-N-methylamino)-, dihydrochloride 14692-56-9
Ethanol, 2-(butylnitrosamino)- 51938-14-8
Ethanol, 2-(butylphenoxy)- 63980-40-5
Ethanol,2-((2-((4-butylphenyl)amino)-6-chloro-9H-purin-9-yl)methoxy)- 104715-78-8
Ethanol,2-((2-((4-butylphenyl)amino)-6-methoxy-9H-purin-9-yl)methoxy)-, hydrate (2:1) 104715-85-7
Ethanol,2-((2-((4-butylphenyl)amino)-9H-purin-9-yl)methoxy)- 104715-83-5
Ethanol, 2-chloro- 107-07-3
Ethanol, 2-chloro-, acetate 542-58-5
Ethanol, 2-(N-(6(and7)-chloro-1,4-benzodioxan-2-ylmethyl)-N-methylamino)- 101221-50-5
Ethanol, 2-((2-chloro-3-benzo(b)thienyl)amino)-,S,S-dioxide 39775-24-1
Ethanol, 2,2'-((2-chloro-3-benzo(b)thienyl)imino)di-,S,S-dioxide 39775-25-2
9,10-Ethanoanthracene,9,10-dihydro-11-((N-(2-dimethylaminoethyl)-N-methyl)amino)methyl-, dihydrochloride 14692-57-0
Ethanol,2-(N-(2-chloro-3-benzo(b)thienyl)methylamino)-,S,S-dioxide 62268-33-1
Ethanol,2-(N-((5-chlorobenzo(b)thien-3-yl)methyl)-N-ethylamino)-, hydrochloride 7349-44-2
Ethanol,2-(((5-chlorobenzo(b)thien-3-yl)methyl)isopropylamino)-, hydrochloride 16584-14-8
Ethanol, 2-(4-(p-chlorobenzyl)phenoxy)- 70930-63-1
Ethanol, 2-(p-chlorobenzylthio)- 71501-40-1
Ethanol,2-((6-chloro-5-(2,3-dibromopropyl)-2-methyl-4-pyrimidinyl)amino)- 85826-40-0
Ethanol,2,2'-((8-chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)imino)bis-, (Z)-2-butenedioate (1:1) 34770-84-8
Ethanol,2-((5-chloro-2,3-dihydro-1H-inden-2-yl)amino)- 34770-84-8
Ethanol,2-((5-chloro-2,3-dihydro-1H-inden-2-yl)methylamino)- 34770-84-8

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