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MSDS  : Ethanol, 2-butoxy-, phosphate (31)
CAS  : 78-51-3
SYNONYMS  : * 2-Butoxyethanol, phosphate * KP 140 * Kronitex KP-140 * Phosflex T-bep * Phosphoric acid, tris(2-butoxyethyl) ester * TBEP * Tri(2-butoxyethanol)phosphate * Tributoxyethyl phosphate * Tri(2-butoxyethyl) phosphate * Tributyl cellosolve phosphate * Tris-(2-butoxyethyl)fosfat * Tris(2-butoxyethyl) phosphate
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : KJ9800000
CHEMICAL NAME : Ethanol, 2-butoxy-, phosphate (3:1)
CAS REGISTRY NUMBER : 78-51-3
BEILSTEIN REFERENCE NO. : 1716010
REFERENCE : 4-01-00-02422 (Beilstein Handbook Reference)
LAST UPDATED : 199710
DATA ITEMS CITED : 17
MOLECULAR FORMULA : C18-H39-O7-P
MOLECULAR WEIGHT : 398.54
WISWESSER LINE NOTATION : 4O2OPO&O2O4&O2O4
COMPOUND DESCRIPTOR : Primary Irritant
SYNONYMS/TRADE NAMES :
* 2-Butoxyethanol, phosphate
* KP 140
* Kronitex KP-140
* Phosflex T-bep
* Phosphoric acid, tris(2-butoxyethyl) ester
* TBEP
* Tri(2-butoxyethanol)phosphate
* Tributoxyethyl phosphate
* Tri(2-butoxyethyl) phosphate
* Tributyl cellosolve phosphate
* Tris-(2-butoxyethyl)fosfat
* Tris(2-butoxyethyl) phosphate

*** HEALTH HAZARD DATA ***

** SKIN/EYE IRRITATION DATA **

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/24H
REACTION SEVERITY : Mild
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1142,1986

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/24H
REACTION SEVERITY : Mild
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1142,1986

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National
Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair
Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015)
Volume(issue)/page/year: 2,93,1975

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010)
Volume(issue)/page/year: NX#00391

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : >16 mL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
28,313,1974

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
29ZWAE "Practical Toxicology of Plastics," Lefaux, R., Cleveland, OH,
Chemical Rubber Co., 1968 Volume(issue)/page/year: -,336,1968

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Bird - chicken
DOSE/DURATION : >5 gm/kg
TOXIC EFFECTS :
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - true cholinesterase
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - phosphatases
REFERENCE :
TIHEEC Toxicology and Industrial Health. (Princeton Scientific Pub. Co.,
POB 2155, Princeton, NJ 08540) V.1- 1985- Volume(issue)/page/year:
6,415,1990

** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 22500 uL/kg/18W-I
TOXIC EFFECTS :
Peripheral Nerve and Sensation - sensory change involving peripheral nerve
Peripheral Nerve and Sensation - recording from peripheral motor nerve
Peripheral Nerve and Sensation - structural change in nerve or sheath
REFERENCE :
JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins
Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981-
Volume(issue)/page/year: 4,42,1984

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 216 gm/kg/14W-C
TOXIC EFFECTS :
Liver - changes in liver weight
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - true cholinesterase
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - other transferases
REFERENCE :
JTSCDR Journal of Toxicological Sciences. (Japanese Soc. of Toxicological
Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku,
Tokyo 113, Japan) V.1- 1976- Volume(issue)/page/year: 18,421,1993

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 15680 uL/kg/14D-I
TOXIC EFFECTS :
Peripheral Nerve and Sensation - recording from afferent nerve
REFERENCE :
CMSHAF Chemosphere. (Pergamon Press Inc., Maxwell House, Fairview Park,
Elmsford, NY 10523) V.1- 1972- Volume(issue)/page/year: 13,801,1984

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 15 gm/kg/3W-I
TOXIC EFFECTS :
Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0528536

*** OCCUPATIONAL EXPOSURE LIMITS ***

OEL-RUSSIA:STEL 1 mg/m3;Skin JAN 1993

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 83871
No. of Facilities: 18954 (estimated)
No. of Industries: 136
No. of Occupations: 50
No. of Employees: 184722 (estimated)

NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 83871
No. of Facilities: 9701 (estimated)
No. of Industries: 90
No. of Occupations: 55
No. of Employees: 257421 (estimated)
No. of Female Employees: 105777 (estimated)

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY

EPA TSCA Section 8(d) unpublished health/safety studies

EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998


*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
Ethanol, 2-tert-butoxy- 7580-85-0
Ethanol, 2-butoxy-, acetate 112-07-2
Ethanol, 2-(2-butoxyethoxy)- 112-34-5
Ethanol, 2-(2-butoxyethoxy)-, acetate 124-17-4
Ethanol, 2-(2-(2-butoxyethoxy)ethoxy)- 143-22-6
Ethanol, 2-(2-butoxyethoxy)-, phthalate 16672-39-2
Ethanol, 2,2'-((4-butoxy-3-nitrobenzyl)imino)di-,hydrochloride 77905-48-7
9,10-Ethanoanthracene,9,10-dihydro-11-(2-(dimethylamino)ethyl)-,hydrochloride 14692-49-0
Ethanol, 2,2'-((5-butoxy-4-penten-2-ynyl)imino)bis- 143337-72-8
Ethanol, 2-butoxy-, phosphate (31) 78-51-3
Ethanol, 2-(6-butoxy-3-pyridylamino)- 78-51-3
Ethanol, 2-butylamino- 111-75-1
Ethanol, 2-tert-butylamino-1-(3-chloro-2-thienyl)- 62673-45-4
Ethanol, 2-tert-butylamino-1-(4-chloro-2-thienyl)- 62673-47-6
Ethanol, 2-tert-butylamino-1-(3,4-dibromo-2-thienyl)- 62673-60-3
Ethanol, 2-tert-butylamino-1-(3,5-dibromo-2-thienyl)- 62673-59-0
Ethanol, 2-tert-butylamino-1-(4,5-dibromo-2-thienyl)- 62673-57-8
Ethanol,2-tert-butylamino-1-(3,5-dichloro-2-thienyl)- 62673-49-8
9,10-Ethanoanthracene,9,10-dihydro-11-(2-(dimethylamino)ethyl)-, methiodide 14692-50-3
Ethanol,2-tert-butylamino-1-(7-ethyl-2-benzofuranyl)-,hydrochloride 59652-29-8
Ethanol,2-tert-butylamino-1-(5-hydroxy-6-hydroxymethyl-2-pyridyl)- 38677-81-5
Ethanol, 2-(butylamino)-1-(p-nitrophenyl)-,hydrochloride 1892-62-2
Ethanol,2-tert-butylamino-1-(3,4,5-tribromo-2-thienyl)- 62673-62-5
Ethanol,2-tert-butylamino-1-(3,4,5-trichloro-2-thienyl)- 62673-51-2
Ethanol, 2-((1-butyl-1H-benzimidazol-2-yl)amino)-,monohydrochloride 111678-89-8
Ethanol,2-(tert-butyl((5-chlorobenzo(b)thien-3-yl)methyl)amino)-, hydrochloride 17512-30-0
Ethanol,2-(tert-butyl((5-fluorobenzo(b)thien-3-yl)methyl)amino)-, hydrochloride 17514-78-2
Ethanol, 2,2'-(butylimino)di- 102-79-4
Ethanol, 2-(butylnitroamino)-, nitrate (ester) 82486-82-6
9,10-Ethanoanthracene,9,10-dihydro-11-(N-(2-dimethylaminoethyl)-N-methylamino)-, dihydrochloride 14692-56-9
Ethanol, 2-(butylnitrosamino)- 51938-14-8
Ethanol, 2-(butylphenoxy)- 63980-40-5
Ethanol,2-((2-((4-butylphenyl)amino)-6-chloro-9H-purin-9-yl)methoxy)- 104715-78-8
Ethanol,2-((2-((4-butylphenyl)amino)-6-methoxy-9H-purin-9-yl)methoxy)-, hydrate (2:1) 104715-85-7
Ethanol,2-((2-((4-butylphenyl)amino)-9H-purin-9-yl)methoxy)- 104715-83-5
Ethanol, 2-chloro- 107-07-3
Ethanol, 2-chloro-, acetate 542-58-5
Ethanol, 2-(N-(6(and7)-chloro-1,4-benzodioxan-2-ylmethyl)-N-methylamino)- 101221-50-5
Ethanol, 2-((2-chloro-3-benzo(b)thienyl)amino)-,S,S-dioxide 39775-24-1
Ethanol, 2,2'-((2-chloro-3-benzo(b)thienyl)imino)di-,S,S-dioxide 39775-25-2
9,10-Ethanoanthracene,9,10-dihydro-11-((N-(2-dimethylaminoethyl)-N-methyl)amino)methyl-, dihydrochloride 14692-57-0
Ethanol,2-(N-(2-chloro-3-benzo(b)thienyl)methylamino)-,S,S-dioxide 62268-33-1
Ethanol,2-(N-((5-chlorobenzo(b)thien-3-yl)methyl)-N-ethylamino)-, hydrochloride 7349-44-2
Ethanol,2-(((5-chlorobenzo(b)thien-3-yl)methyl)isopropylamino)-, hydrochloride 16584-14-8
Ethanol, 2-(4-(p-chlorobenzyl)phenoxy)- 70930-63-1
Ethanol, 2-(p-chlorobenzylthio)- 71501-40-1
Ethanol,2-((6-chloro-5-(2,3-dibromopropyl)-2-methyl-4-pyrimidinyl)amino)- 85826-40-0
Ethanol,2,2'-((8-chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)imino)bis-, (Z)-2-butenedioate (1:1) 34770-84-8
Ethanol,2-((5-chloro-2,3-dihydro-1H-inden-2-yl)amino)- 34770-84-8
Ethanol,2-((5-chloro-2,3-dihydro-1H-inden-2-yl)methylamino)- 34770-84-8

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