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MSDS  : Acrylamide, N-(isobutoxymethyl)-
CAS  : 16669-59-3
SYNONYMS  : * N-Isobutoxymethylacrylamide * N-((2-Methylpropoxy)methyl)-2-propenamide * 2-Propenamide, N-((2-methylpropoxy)methyl)-
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : AS3630000
CHEMICAL NAME : Acrylamide, N-(isobutoxymethyl)-
CAS REGISTRY NUMBER : 16669-59-3
LAST UPDATED : 199701
DATA ITEMS CITED : 7
MOLECULAR FORMULA : C8-H15-N-O2
MOLECULAR WEIGHT : 157.24
WISWESSER LINE NOTATION : 1Y1&1O1MV1U1
COMPOUND DESCRIPTOR : Primary Irritant
SYNONYMS/TRADE NAMES :
* N-Isobutoxymethylacrylamide
* N-((2-Methylpropoxy)methyl)-2-propenamide
* 2-Propenamide, N-((2-methylpropoxy)methyl)-

*** HEALTH HAZARD DATA ***

** SKIN/EYE IRRITATION DATA **

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg
REACTION SEVERITY : Mild
REFERENCE :
ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology,
Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-
1990- Volume(issue)/page/year: 1,112,1990

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg
REACTION SEVERITY : Mild
REFERENCE :
ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology,
Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-
1990- Volume(issue)/page/year: 1,112,1990

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1020 uL/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Lungs, Thorax, or Respiration - other changes
Liver - other changes
REFERENCE :
ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology,
Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-
1990- Volume(issue)/page/year: 1,112,1990

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 645 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000
Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year:
47,179,1981

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 884 uL/kg
TOXIC EFFECTS :
Behavioral - tremor
Lungs, Thorax, or Respiration - other changes
Kidney, Ureter, Bladder - other changes
REFERENCE :
ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology,
Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-
1990- Volume(issue)/page/year: 1,112,1990

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X4311
No. of Facilities: 17 (estimated)
No. of Industries: 1
No. of Occupations: 1
No. of Employees: 425 (estimated)
No. of Female Employees: 17 (estimated)

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY


*** END OF RECORD ***
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