RTECS NUMBER : AS3700000
CHEMICAL NAME : Acrylamide, polymers
CAS REGISTRY NUMBER : 9003-05-8
LAST UPDATED : 199710
DATA ITEMS CITED : 10
MOLECULAR FORMULA : (C3-H5-N-O)x
SYNONYMS/TRADE NAMES :
* Polyacrylamide
* 2-Propenamide, homopolymer
* PAA
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : >1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
WATRAG Water Research. (Pergamon Press Ltd., Headington Hill Hall, Oxford
OX3 0BW, UK) V.1- 1967- Volume(issue)/page/year: 24,661,1990
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 3600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 46(4),79,1981
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 12950 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Behavioral - ataxia
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 29(12),20,1964
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 11250 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Behavioral - ataxia
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 29(12),20,1964
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 4200 mg/kg/28D-C
TOXIC EFFECTS :
Blood - pigmented or nucleated red blood cells
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - true cholinesterase
REFERENCE :
WATRAG Water Research. (Pergamon Press Ltd., Headington Hill Hall, Oxford
OX3 0BW, UK) V.1- 1967- Volume(issue)/page/year: 24,661,1990
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - A1311
No. of Facilities: 245 (estimated)
No. of Industries: 7
No. of Occupations: 10
No. of Employees: 459 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X6599
No. of Facilities: 1643 (estimated)
No. of Industries: 31
No. of Occupations: 29
No. of Employees: 36387 (estimated)
No. of Female Employees: 3824 (estimated)