*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : MD0911500
CHEMICAL NAME : Glycols, polyethylene-polypropylene, poloxamer-188
CAS REGISTRY NUMBER : 9003-11-6
LAST UPDATED : 199710
DATA ITEMS CITED : 12
MOLECULAR FORMULA : (C3-H6-O.C2-H4-O)x
SYNONYMS/TRADE NAMES :
* alpha-Hydro-omega-hydroxypoly(oxyethylene)poly(oxypropylene)poly(oxyethy
lene)
* Poloxamer-188
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : >30300 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka
Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959-
Volume(issue)/page/year: 23,2291,1981
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 6900 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,797,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 7500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho
Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970-
Volume(issue)/page/year: 12,1204,1981
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : >30300 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka
Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959-
Volume(issue)/page/year: 23,2291,1981
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 5500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,797,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,797,1982
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - M3966
No. of Facilities: 6846 (estimated)
No. of Industries: 44
No. of Occupations: 37
No. of Employees: 38016 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X7313
No. of Facilities: 59555 (estimated)
No. of Industries: 299
No. of Occupations: 176
No. of Employees: 1005983 (estimated)
No. of Female Employees: 296376 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-9175
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
Glycols, polyethylene-polypropylene, pluronic F68
| 9003-11-6 |
Glycols, polythylene-polypropylene, pluronic L44
| 9003-11-6 |
Glycols, polyethylene-polypropylene, pluronic L62
| 9003-11-6 |
Glycols, polyethylene-polypropylene, pluronic L64
| 9003-11-6 |
Glycols, polyethylene-polypropylene, pluronic L-81
| 9003-11-6 |
Glycine, 1,1'-(1,7-dioxo-1,7-heptanediyl)bis(glycyl-
| 143673-92-1 |
Glycols, polyethylene-polypropylene, poloxamer-188
| 9003-11-6 |
Glycols, polyethylene-polypropylene, RC 102
| 9003-11-6 |
Glycols, polypropylene, bis(2-aminopropyl) ether, DA200SUBSTANCE DEFINITION :With a molecular weight of 200REFERENCE :GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene andOccupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)V.1-36, 1957-1992. For publisher information, see MTPEEI
| 9003-11-6 |
Glycols, polypropylene, bis(2-aminopropyl) ether,DA-500SUBSTANCE DEFINITION :With a molecular weight of 500REFERENCE :GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/OMezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
| 9003-11-6 |
Glycols, polypropylene, bis(2-aminopropyl) ether, DA1000SUBSTANCE DEFINITION :With a molecular weight of 1000REFERENCE :GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene andOccupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)V.1-36, 1957-1992. For publisher information, see MTPEEI
| 9003-11-6 |
Glycols, polypropylene, 1,2,3-propanetriyl ether
| 25791-96-2 |
Glycols, polypropylene, tris(2-aminopropyl) ether,TA750SUBSTANCE DEFINITION :With a molecular weight of 750REFERENCE :GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene andOccupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)V.1-36, 1957-1992. For publisher information, see MTPEEI
| 25791-96-2 |
Glycols, polypropylene, tris(2-aminopropyl) ether,TA-1100SUBSTANCE DEFINITION :With a molecular weight of 1100REFERENCE :GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/OMezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
| 25791-96-2 |
Glycols, polypropylene, tris(2-aminopropyl) ether,TA1500SUBSTANCE DEFINITION :With a molecular weight of 1500REFERENCE :GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene andOccupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)V.1-36, 1957-1992. For publisher information, see MTPEEI
| 25791-96-2 |
Glycols, polytetramethylene
| 25190-06-1 |
Glycine, N,N-dimethyl-,((2,3-dihydro-6-chloroimidazo(2,1-b)thiazol-5-yl)methylene)hydrazide
| 102410-40-2 |
Glycine, N,N'-(1,6-dioxo-1,6-hexanediyl)bis-
| 91717-13-4 |
Glycoluril, 3a,6a-dimethyl-
| 28115-25-5 |
Glycoluril, 3a,6a-diphenyl-
| 5157-15-3 |
Glycoluril, 1,3,4,6-tetrachloro-3a,6a-diphenyl-
| 51592-06-4 |
Glycoprotein toxins, from Candida albicansSUBSTANCE DEFINITION :Glycoprotein complex isolated from the cell walls of the 29-3-109 strain ofCandida albicansREFERENCE :40YJAX "Evaluation of Embryotoxicity, Mutagenicity and Carcinogenicity RisksIn New Drugs, Proceedings of the Symposium on Toxicological Testing forSafety of New Drugs, 3rd, Prague, 1976," Benesova, O., et al., eds., Prague,Czechoslovakia, Univerzita Karlova, 1979
| 51592-06-4 |
Glycosmis arborea (roxb.) DC., extract excludingrootsSUBSTANCE DEFINITION :Plant belonging to the family RutaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 51592-06-4 |
Glycosmis mauritiana (lam.) Tanaka, root extractSUBSTANCE DEFINITION :Plant belonging to the family RutaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 51592-06-4 |
Glycosmis mauritiana (Lam.) Tanaka var. andamanensis(Naray.) Tanaka, extractSUBSTANCE DEFINITION :Plant belonging to the family RutaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 28,619,1990
| 51592-06-4 |
Glycosmis pentaphylla Correa, extractSUBSTANCE DEFINITION :Plant belonging to the family RutaceaeREFERENCE :CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA,1255 Howard St., San Francisco, CA 94103) V.6- 1958-
| 51592-06-4 |
Glycyrrhiza extract
| 68916-91-6 |
Glycyrrhiza glabra Linn., root extractSUBSTANCE DEFINITION :Plant belonging to the family FabaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 22,312,1984
| 68916-91-6 |
Glycine, N,N'-(1,6-dioxo-1,6-hexanediyl)bis-, diethylester
| 92377-71-4 |
Glycyrrhiza uralensis Fish., extract
| 92377-71-4 |
Glycyrrhizinic acid
| 1405-86-3 |
Glyoxal
| 107-22-2 |
Glyoxal, 29.2%
| 107-22-2 |
Glyoxal, 40%
| 107-22-2 |
Glyoxal, biphenylyl-, diethyl hydrazone
| 24342-51-6 |
Glyoxal, bis(ethoxycarbonylamido-
| 35896-51-6 |
Glyoxal, p-chlorophenyl-, diethyl hydrazone
| 24346-21-2 |
Glyoxal, p-chlorophenyl-, dimethyl hydrazone
| 24346-19-8 |
Glyoxal, (3,4-dihydroxyphenyl)-, dioxime
| 65561-73-1 |
Glycine, N,N'-(1,9-dioxo-1,9-nonanediyl)bis-
| 143673-89-6 |
Glyoxal, dioxime
| 557-30-2 |
Glyoxal, p-methoxyphenyl-, dimethyl hydrazone
| 25555-11-7 |
Glyoxal, p-nitrophenyl-, diethyl hydrazone
| 24342-44-7 |
Glyoxal, p-nitrophenyl-, dimethyl hydrazone
| 25555-13-9 |
Glyoxal, (p-phenethylphenyl)-
| 24585-99-7 |
Glyoxal, (p-phenethylphenyl)-, compd. with sodiumbisulfite
| 2983-58-6 |
Glyoxal, (p-phenoxyphenyl)-
| 70-97-3 |
Glyoxal, p-phenoxyphenyl-, dimethyl hydrazone
| 24346-20-1 |
Glyoxal, phenyl-
| 1074-12-0 |
Glyoxal, phenyl-, 2-(diethyl acetal)
| 6175-45-7 |
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