RTECS NUMBER : PB9268200
CHEMICAL NAME : 1,5-Methano-1H,3H,11H-furo(3,4-g)pyrano(3,2-b)xanthen
e-1-crotonic acid, 3a,4,5,7-tetrahydro-
8-hydroxy-alpha,3,3,11-tetramethyl-13-(3-methyl-2-but
enyl)-11-(4-methyl-3- pentenyl)-7,15- dioxo-, (Z)-
CAS REGISTRY NUMBER : 2752-65-0
LAST UPDATED : 199503
DATA ITEMS CITED : 4
MOLECULAR FORMULA : C38-H44-O8
MOLECULAR WEIGHT : 628.82
COMPOUND DESCRIPTOR : Drug
Natural Product
SYNONYMS/TRADE NAMES :
* Cambogic acid
* beta-Guttiferin
* B''-Guttiferin
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 88 mg/kg
TOXIC EFFECTS :
Liver - other changes
REFERENCE :
IJEBA6 Indian Journal of Experimental Biology. (Publications & Information
Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
Volume(issue)/page/year: 5,96,1967
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 107 mg/kg
TOXIC EFFECTS :
Liver - other changes
REFERENCE :
IJEBA6 Indian Journal of Experimental Biology. (Publications & Information
Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
Volume(issue)/page/year: 5,96,1967
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 354 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca
Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 8(1),331,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Mammal - species unspecified
DOSE/DURATION : 55 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85PEAG "Zhongliu Yanjiu" Cancer Review, Yu, R., et al., eds., Shanghai
Science/Technology Publisher, Peop. Rep. China, 1994
Volume(issue)/page/year: -,220,1994
*** END OF RECORD ***
ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP