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MSDS  : Phenol, 2-cyclohexyl-4,6-dinitro-
CAS  : 131-89-5
SYNONYMS  : * 6-Cicloesil-2,4-dinitr-fenolo * 2-Cyclohexyl-4,6-dinitrofenol * 2-Cyclohexyl-4,6-dinitrophenol * 6-Cyclohexyl-2,4-dinitrophenol * Dinex * Dinitrocyclohexylphenol * Dinitro-o-cyclohexylphenol * 2,4-Dinitro-6-cyclohexylphenol * 4,6-Dinitro-o-cyclohexylphenol * DN * DN 1 * Dn Dry Mix No. 1 * Dn Dust No. 12 * DNOCHP * Dowspray 17 * Dry mix No. 1 * ENT 157 * Pedinex * Phenol, 6-cyclohexyl-2,4-dinitro- * RCRA waste number P034 * SN 46
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : SK6650000
CHEMICAL NAME : Phenol, 2-cyclohexyl-4,6-dinitro-
CAS REGISTRY NUMBER : 131-89-5
BEILSTEIN REFERENCE NO. : 2005960
REFERENCE : 4-06-00-03903 (Beilstein Handbook Reference)
LAST UPDATED : 199710
DATA ITEMS CITED : 20
MOLECULAR FORMULA : C12-H14-N2-O5
MOLECULAR WEIGHT : 266.28
WISWESSER LINE NOTATION : L6TJ AR BQ CNW ENW
COMPOUND DESCRIPTOR : Agricultural Chemical
Primary Irritant
SYNONYMS/TRADE NAMES :
* 6-Cicloesil-2,4-dinitr-fenolo
* 2-Cyclohexyl-4,6-dinitrofenol
* 2-Cyclohexyl-4,6-dinitrophenol
* 6-Cyclohexyl-2,4-dinitrophenol
* Dinex
* Dinitrocyclohexylphenol
* Dinitro-o-cyclohexylphenol
* 2,4-Dinitro-6-cyclohexylphenol
* 4,6-Dinitro-o-cyclohexylphenol
* DN
* DN 1
* Dn Dry Mix No. 1
* Dn Dust No. 12
* DNOCHP
* Dowspray 17
* Dry mix No. 1
* ENT 157
* Pedinex
* Phenol, 6-cyclohexyl-2,4-dinitro-
* RCRA waste number P034
* SN 46

*** HEALTH HAZARD DATA ***

** SKIN/EYE IRRITATION DATA **

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 105 mg/9D (Intermittent)
REACTION SEVERITY : Moderate
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA)
V.18-31, 1936-49. For publisher information, see AEHLAU.
Volume(issue)/page/year: 30,10,1948

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 65 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARSIM* Agricultural Research Service, USDA Information Memorandum.
(Beltsville, MD 20705) Volume(issue)/page/year: 20,9,1966

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85DPAN "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel,"
Perkow, W., Berlin, Verlag Paul Parey, 1971-1976 Volume(issue)/page/year:
-,-,1971/1976

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 25 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year:
18,1389,1969

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 30 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes
REFERENCE :
UCPHAQ University of California, Berkeley, Publications in Pharmacology.
(Berkeley, CA) V.1-3, 1938-57. Discontinued. Volume(issue)/page/year:
1,151,1939

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 20 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 53,58,1935

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 8 mg/kg
TOXIC EFFECTS :
Cardiac - arrhythmias (including changes in conduction)
Lungs, Thorax, or Respiration - dyspnea
Nutritional and Gross Metabolic - body temperature increase
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 50,20,1935

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 81 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0536145

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 40 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - other changes
Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
UCPHAQ University of California, Berkeley, Publications in Pharmacology.
(Berkeley, CA) V.1-3, 1938-57. Discontinued. Volume(issue)/page/year:
1,151,1939

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCOC** Pesticide Chemicals Official Compendium, Association of the American
Pesticide Control Officials, Inc., 1966. (Topeka, KS)
Volume(issue)/page/year: -,417,1966

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCOC** Pesticide Chemicals Official Compendium, Association of the American
Pesticide Control Officials, Inc., 1966. (Topeka, KS)
Volume(issue)/page/year: -,417,1966

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 20 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCOC** Pesticide Chemicals Official Compendium, Association of the American
Pesticide Control Officials, Inc., 1966. (Topeka, KS)
Volume(issue)/page/year: -,417,1966

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Bird - pigeon
DOSE/DURATION : 7 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 50,20,1935

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Bird - pigeon
DOSE/DURATION : 8 mg/kg
TOXIC EFFECTS :
Nutritional and Gross Metabolic - body temperature increase
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 53,58,1935

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Bird - chicken
DOSE/DURATION : 76 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0536145

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Mammal - species unspecified
DOSE/DURATION : 50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag
New York, Inc., 1971 Volume(issue)/page/year: -,101,1971

** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 4200 mg/kg/2W-C
TOXIC EFFECTS :
Related to Chronic Data - death
REFERENCE :
UCPHAQ University of California, Berkeley, Publications in Pharmacology.
(Berkeley, CA) V.1-3, 1938-57. Discontinued. Volume(issue)/page/year:
1,151,1939

*** STATUS IN U.S. ***

EPA TSCA Section 8(d) unpublished health/safety studies

On EPA IRIS database

EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998


*** END OF RECORD ***
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NAMECAS
Phenol, 4-chloro-2-ethyl- 18979-90-3
Phenol, 4-chloro-2-ethyl-, acetate 53347-16-3
Phenol, 2-(((2-chloroethyl)amino)methyl)-4-nitro- 56538-00-2
Phenol, 4-chloro-2-ethyl-6-nitro- 53347-03-8
Phenol, 4-chloro-2-ethyl-6-propyl- 53346-77-3
Phenol, 4-chloro-2-hexyl- 18979-94-7
Phenol,4-chloro-2-((2-fluorophenyl)(pentylimino)methyl)- 18979-94-7
Phenol,4-((7-chloro-2-methoxybenzo(b)-1,5-naphthyridin-10-yl)amino)-2,6-bis(1-pyr rolidinyl methyl)-, phosphate(1:4) 76748-86-2
Phenol, 4-amino-2-nitro- 119-34-6
Phenol, 2-(2-chloro-1-methoxyethoxy)-,methylcarbamate 51487-69-5
Phenol,4-(2-((3-(2-chloro-4-(2-methoxyethyl)phenoxy)-2-hydroxypropyl)amino)propyl )-, hydrochloride 74027-40-0
Phenol, 2-chloro-5-methyl- 615-74-7
Phenol, 4-(chloromethyl)-, acetate 39720-27-9
Phenol, 3-(1-chloro-2-(methylamino)ethyl)-,hydrochloride 39720-27-9
Phenol, 4-chloro-3-methyl-2-(1-methylethyl)- 39720-27-9
Phenol, 2-(chloromethyl)-4-nitro- 2973-19-5
Phenol, 2-chloro-4-(methylsulfonyl)- 20945-65-7
Phenol, 2-chloro-4-nitro- 619-08-9
Phenol, 3-chloro-4-nitro- 491-11-2
Phenol, 2-amino-4-nitro-, hydrochloride 65407-97-8
Phenol, 2-chloro-4-nitro-, sodium salt 38731-70-3
Phenol, 4-chloro-2-(phenylmethyl)-, sodium salt 3184-65-4
Phenol,2-(5-((4-chlorophenyl)amino)-4-phenyl-4H-1,2,4-triazol-3-yl)- 82619-90-7
Phenol, p-((p-chlorophenyl)azo)- 2703-27-7
Phenol, 2-chloro-4-(phenylazo)- 6657-05-2
Phenol, p-((p-chlorophenyl)azo)-, piperazine salt 6657-05-2
Phenol,o-(4-(m-chlorophenyl)-3H-1,5-benzodiazepin-2-yl)- 6657-05-2
Phenol,o-(4-(o-chlorophenyl)-3H-1,5-benzodiazepin-2-yl)- 6657-05-2
Phenol,o-(4-(p-chlorophenyl)-3H-1,5-benzodiazepin-2-yl)- 6657-05-2
Phenol, 4-chloro-2-(phenylmethyl)-, potassium salt 35471-49-9
Phenol, 4-amino-2-nitro-, hydrochloride 35471-49-9
Phenol,2-((2-chlorophenyl)(pentylimino)methyl)-4-fluoro- 35471-49-9
Phenol, 4-(6-chloro-4-phenyl-2-quinazolinyl)- 49797-12-8
Phenol, p-chloro-, potassium salt 1121-74-0
Phenol,4-((7-chloro-4-quinolinyl)amino)-2,6-bis(1-pyrrolidinylmethyl)-, trihydrochloride 86489-54-5
Phenol,4-((7-chloro-4-quinolinyl)amino)-2-(phenyl-1-piperidinylmethyl)- 59614-92-5
Phenol,2,2'-(((6-chloro-2-quinoxalinyl)methylene)bis(3-(1,1-dimethylethyl)-4-meth oxy-, N,N'-dioxide 105301-24-4
Phenol,3-chloro-2-(4,5,6,7-tetrahydro-4,7-methanoisoindol-2-yl)-6-nitro- 78593-84-7
Phenol,2-(7-chloro-4H-(1,2,4)triazolo(3,4-c)(1,4)benzothiazin-1-yl)- 93300-02-8
Phenol, p-chloro-m-trifluoromethyl- 6294-93-5
Phenol, 3-(2-chloro-4-(trifluoromethyl)phenoxy)-,acetate 50594-77-9
Phenol, 2-amino-4-nitro-, sodium salt 61702-43-0
Phenol,2,2'-(2-(p-cyanophenyl)-1,3-imidazolidenedimethylene)di- 20063-36-9
Phenol,3-(6-(cyclobutylmethyl)-6-azabicyclo(3.2.1)oct-1-yl)-, hydrochloride, (+-)- 61226-57-1
Phenol, p-(1-cyclohexen-1-yl)- 709-08-0
Phenol, 2-(3-cyclohexenyl)-4,6-dinitro- 73758-38-0
Phenol, 2-((cyclohexylamino)methyl)-6-methoxy- 59004-61-4
Phenol, 2-cyclohexyl-4,6-dinitro- 131-89-5
Phenol, 2-cyclohexyl-4,6-dinitro-, Compd withdicylohexylamine 317-83-9
Phenol, 4,4'-(cyclohexylidenemethylene)di-,bis(dihydrogen phosphate) tetrasodium salt 15480-76-9

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