RTECS NUMBER : TH2800000
CHEMICAL NAME : Phosphorous acid, tris(1-methylethyl) ester
CAS REGISTRY NUMBER : 116-17-6
BEILSTEIN REFERENCE NO. : 1701528
REFERENCE : 4-01-00-01476 (Beilstein Handbook Reference)
LAST UPDATED : 199710
DATA ITEMS CITED : 7
MOLECULAR FORMULA : C9-H21-O3-P
MOLECULAR WEIGHT : 208.27
WISWESSER LINE NOTATION : 1Y1&OPOY1&1&OY1&1
COMPOUND DESCRIPTOR : Mutagen
SYNONYMS/TRADE NAMES :
* Isopropyl phosphite ((C3H7O)3P)
* Isopropyl phosphite, tri-
* Phosphorous acid, triisopropyl ester
* Triisopropoxyphosphine
* Triisopropyl phosphite
* Tri-2-propylphosphite
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 167 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ALBRW* Albright & Wilson Inc. (P.O. Box 26229, Richmond, VA 23260-6229)
Volume(issue)/page/year: #OPB-3,1984
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CBCCT* "Summary Tables of Biological Tests," National Research Council
Chemical-Biological Coordination Center. (National Academy of Science
Library, 2101 Constitution Ave., NW, Washington, DC 20418)
Volume(issue)/page/year: 9,130,1957
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : >2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ALBRW* Albright & Wilson Inc. (P.O. Box 26229, Richmond, VA 23260-6229)
Volume(issue)/page/year: #OPB-3,1984
** MUTATION DATA **
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 5 mg/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 28,405,1975
TYPE OF TEST : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE : Oral
TEST SYSTEM : Insect - Drosophila melanogaster
DOSE/DURATION : 50 mmol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 28,405,1975
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***
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