*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : TJ3494000
CHEMICAL NAME : Phytolacca dodecandra, extract
CAS REGISTRY NUMBER : 39278-85-8
LAST UPDATED : 199410
DATA ITEMS CITED : 9
COMPOUND DESCRIPTOR : Mutagen
Reproductive Effector
Natural Product
SYNONYMS/TRADE NAMES :
* Endod, extract
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BWHOA6 Bulletin of the World Health Organization. (WHO, Pub. Center USA, 49
Sheridan Ave., Albany, NY 12210) Volume(issue)/page/year: 42,597,1970
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BWHOA6 Bulletin of the World Health Organization. (WHO, Pub. Center USA, 49
Sheridan Ave., Albany, NY 12210) Volume(issue)/page/year: 42,597,1970
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Primate - monkey
DOSE/DURATION : 3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BWHOA6 Bulletin of the World Health Organization. (WHO, Pub. Center USA, 49
Sheridan Ave., Albany, NY 12210) Volume(issue)/page/year: 42,597,1970
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Bird - chicken
DOSE/DURATION : 2500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BWHOA6 Bulletin of the World Health Organization. (WHO, Pub. Center USA, 49
Sheridan Ave., Albany, NY 12210) Volume(issue)/page/year: 42,597,1970
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - domestic
DOSE/DURATION : 7800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BWHOA6 Bulletin of the World Health Organization. (WHO, Pub. Center USA, 49
Sheridan Ave., Albany, NY 12210) Volume(issue)/page/year: 42,597,1970
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intrauterine
SPECIES OBSERVED : Rodent - rat
DOSE : 2500 ug/kg
SEX/DURATION : female 4 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
number of implants per female; total number of implants per corpora lutea)
REFERENCE :
CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1-
1970- Volume(issue)/page/year: 14,39,1976
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intrauterine
SPECIES OBSERVED : Rodent - rat
DOSE : 500 ug/kg
SEX/DURATION : female 6 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
REFERENCE :
CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1-
1970- Volume(issue)/page/year: 14,39,1976
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intrauterine
SPECIES OBSERVED : Rodent - rat
DOSE : 500 ug/kg
SEX/DURATION : female 1 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - female fertility index (e.g. # females pregnant
per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1-
1970- Volume(issue)/page/year: 14,39,1976
** MUTATION DATA **
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 100 mg/plate
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For
publisher information, see EMMUEG. Volume(issue)/page/year: 5,687,1983
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
Phyllanthus polyphyllus Willd., extract excludingrootsSUBSTANCE DEFINITION :Plant belonging to the family EuphorbiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 12,512,1974
| 110406-46-7 |
Phyllanthus reticulatus Pain., extract exluding rootSUBSTANCE DEFINITION :Plant belonging to the family EuphorbiaceaeREFERENCE :JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. IrelandLtd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year:30,233,1990
| 110406-46-7 |
Phyllochlamys spinosa Bureau, extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family MoraceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 110406-46-7 |
Phyllomycin
| 101997-25-5 |
Physalin-X
| 72497-31-5 |
Physalis alkekengi L., extractSUBSTANCE DEFINITION :Plant belonging to the family SolanaceaeREFERENCE :JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. IrelandLtd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year:34,69,1991
| 72497-31-5 |
Physalis peruviana Linn., extractSUBSTANCE DEFINITION :Plant belonging to the family SolanaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 72497-31-5 |
1(2H)-Phthalazinone,4-((4-chlorophenyl)methyl)-2-(8-(phenylmethyl)-8-azabicyclo(3.2.1)oct-3- yl)-, monohydrochloride
| 110406-75-2 |
Physalis pubescens L., extractSUBSTANCE DEFINITION :African plant belonging to the family SolanaceesREFERENCE :JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. IrelandLtd., POB 85, Limerick, Ireland) V.1- 1979-
| 110406-75-2 |
Physaria vitalifera Rydb., alkaloid extractSUBSTANCE DEFINITION :Alkaloids obtained from the plant belonging to the family CruciferaeREFERENCE :JNPRDF Journal of Natural Products. (Spahr & Glenn Co., 225 E. Spring St.,Columbus, OH 43215) V.42- 1979- Volume(issue)/page/year: 44,693,1981
| 110406-75-2 |
Physiosol 1-L
| 110406-75-2 |
Physiosol 1-S
| 110406-75-2 |
Physodine A
| 122051-33-6 |
Physodine B
| 122051-34-7 |
Physostigmine
| 57-47-6 |
Physostigmine, methiodide
| 6091-11-8 |
Physostigmine, salicylate (11)
| 57-64-7 |
Physostigmine, tartrate
| 57-64-7 |
1(2H)-Phthalazinone,2-(8-(cyclohexylmethyl)-8-azabicyclo(3.2.1)oct-3-yl)-4-((4-fluorophenyl) methyl)-
| 110406-71-8 |
Phytic acid, hexacopper (II) salt
| 63903-50-4 |
Phytohemagglutinin
| 9008-97-3 |
Phytohemagglutinin, dolichos lablab
| 9008-97-3 |
Phytohemagglutinin, phaseolus lunatus
| 9008-97-3 |
Phytohemagglutinin, pisum sp.
| 9008-97-3 |
Phytol
| 150-86-7 |
Phytolacca acinosa Roxb., extractSUBSTANCE DEFINITION :Plant belonging to the family PhytolacaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 150-86-7 |
Phytolacca americana Linn., root extract
| 150-86-7 |
Phytolacca dodecandra, extract
| 39278-85-8 |
Phytolacca dodecandra L'Herit, extractSUBSTANCE DEFINITION :African plant belonging to the family PhytolaccaceesREFERENCE :JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. IrelandLtd., POB 85, Limerick, Ireland) V.1- 1979-
| 39278-85-8 |
1(2H)-Phthalazinone, 8-amino-4-methyl-2-phenyl-
| 16676-83-8 |
1(2H)-Phthalazinone,2-(8-(3-cyclohexyl-3-oxopropyl)-8-azabicyclo(3.2.1)oct-3-yl)-4- ((4-fluorophenyl)methyl)-,monohydrochloride
| 110406-73-0 |
Phytolacca dodecandra L'Herit, root extractSUBSTANCE DEFINITION :Plant belonging to the family PhytolaccaceesREFERENCE :JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. IrelandLtd., POB 85, Limerick, Ireland) V.1- 1979-
| 110406-73-0 |
PhytonSUBSTANCE DEFINITION :Fungicide containing copperREFERENCE :GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/OMezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-Volume(issue)/page/year: 52(8),25,1987
| 110406-73-0 |
Phyton-27
| 73070-37-8 |
Picea abies (linn.) Karst., extract excluding roots
| 91770-69-3 |
Picea morinda Link., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family PinaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 91770-69-3 |
Picene
| 213-46-7 |
Pichia fermentans, glucan extractSUBSTANCE DEFINITION :A yeast belonging to the Saccharomycetaceae familyREFERENCE :USXXAM United States Patent Document. (U.S. Patent Office, Box 9,Washington, DC 20231)
| 213-46-7 |
Picibanil
| 39325-01-4 |
Picnomon arcana Cass., flower extract
| 39325-01-4 |
Picolinaldehyde, bis(2-chloroethyl)hydrazone
| 7606-04-4 |
1(2H)-Phthalazinone,2-(8-(cyclopropylmethyl)-8-azabicyclo(3.2.1)oct-3-yl)-4- ((4-fluorophenyl)methyl)-, monohydrochloride
| 110406-72-9 |
Picolinaldehyde, 1,6-dihydro-1-methyl-, oxime,hydrochloride
| 57619-29-1 |
Picolinaldehyde, 5-hydroxy-, thiosemicarbazone
| 19494-89-4 |
Picolinaldehyde, oxime
| 873-69-8 |
Picolinaldehyde, thiosemicarbazone
| 3608-75-1 |
Picolinamide, N-(1-adamantyl)-
| 61876-32-2 |
Picolinamide, N-(2-(1-adamantyl)ethyl)-,hydrochloride
| 61876-34-4 |
Picolinamide, N-(p-(1-adamantyl)phenyl)-,hydrochloride
| 61876-33-3 |
Picolinamide, 5-butyl-N-(2-(diethylamino)ethyl)-,hydrochloride
| 66715-48-8 |
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