*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : TJ3470000
CHEMICAL NAME : Phytohemagglutinin
CAS REGISTRY NUMBER : 9008-97-3
LAST UPDATED : 199504
DATA ITEMS CITED : 8
COMPOUND DESCRIPTOR : Drug
Mutagen
Reproductive Effector
Natural Product
SYNONYMS/TRADE NAMES :
* Fitohemaglutynina
* PHA
* Phytohaemagglutinin
* Phytohemaglutinins
* Pigeon pea phytohemagglutinin
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1470 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - food intake (animal)
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
40,217,1977
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE : 10 mg/kg
SEX/DURATION : female 4-5 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
REFERENCE :
FOBGA8 Folia Biologica (Krakow). (Ars Polona, POB 1001, 00-068 Warsaw 1,
Poland) V.1- 1953- Volume(issue)/page/year: 24,213,1976
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE : 120 mg/kg
SEX/DURATION : female 4-5 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
REFERENCE :
FOBGA8 Folia Biologica (Krakow). (Ars Polona, POB 1001, 00-068 Warsaw 1,
Poland) V.1- 1953- Volume(issue)/page/year: 24,213,1976
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE : 20 mg/kg
SEX/DURATION : female 11-12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
Reproductive - Specific Developmental Abnormalities - cardiovascular
(circulatory) system
REFERENCE :
FOBGA8 Folia Biologica (Krakow). (Ars Polona, POB 1001, 00-068 Warsaw 1,
Poland) V.1- 1953- Volume(issue)/page/year: 24,213,1976
** MUTATION DATA **
TYPE OF TEST : Mutation test systems - not otherwise specified
TEST SYSTEM : Rodent - rat Lymphocyte
DOSE/DURATION : 1 mg/L
REFERENCE :
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E.
11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year:
17,141,1991
TYPE OF TEST : Unscheduled DNA synthesis
TEST SYSTEM : Rodent - mouse Lymphocyte
DOSE/DURATION : 10 mg/L
REFERENCE :
PLMEAA Planta Medica. (Georg Thieme Verlag, Postfach 732, D-7000 Stuttgart
1, Fed. Rep. Ger.) V.1- 1953- Volume(issue)/page/year: 51,91,1985
TYPE OF TEST : Cytogenetic analysis
TEST SYSTEM : Rodent - mouse Cells - not otherwise specified
DOSE/DURATION : 40 uL/plate
REFERENCE :
FOMOAJ Folia Morphologica (Warsaw). (Panstwowy Zaklad Wydawnictw
Lekarskich, ul. Dluga 38-40, 00 238 Warsaw, Poland) V.1- 1929-
Volume(issue)/page/year: 33,191,1974
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X9999
No. of Facilities: 56 (estimated)
No. of Industries: 1
No. of Occupations: 1
No. of Employees: 265 (estimated)
No. of Female Employees: 215 (estimated)
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
Phyllanthus polyphyllus Willd., extract excludingrootsSUBSTANCE DEFINITION :Plant belonging to the family EuphorbiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 12,512,1974
| 110406-46-7 |
Phyllanthus reticulatus Pain., extract exluding rootSUBSTANCE DEFINITION :Plant belonging to the family EuphorbiaceaeREFERENCE :JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. IrelandLtd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year:30,233,1990
| 110406-46-7 |
Phyllochlamys spinosa Bureau, extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family MoraceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 110406-46-7 |
Phyllomycin
| 101997-25-5 |
Physalin-X
| 72497-31-5 |
Physalis alkekengi L., extractSUBSTANCE DEFINITION :Plant belonging to the family SolanaceaeREFERENCE :JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. IrelandLtd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year:34,69,1991
| 72497-31-5 |
Physalis peruviana Linn., extractSUBSTANCE DEFINITION :Plant belonging to the family SolanaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 72497-31-5 |
1(2H)-Phthalazinone,4-((4-chlorophenyl)methyl)-2-(8-(phenylmethyl)-8-azabicyclo(3.2.1)oct-3- yl)-, monohydrochloride
| 110406-75-2 |
Physalis pubescens L., extractSUBSTANCE DEFINITION :African plant belonging to the family SolanaceesREFERENCE :JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. IrelandLtd., POB 85, Limerick, Ireland) V.1- 1979-
| 110406-75-2 |
Physaria vitalifera Rydb., alkaloid extractSUBSTANCE DEFINITION :Alkaloids obtained from the plant belonging to the family CruciferaeREFERENCE :JNPRDF Journal of Natural Products. (Spahr & Glenn Co., 225 E. Spring St.,Columbus, OH 43215) V.42- 1979- Volume(issue)/page/year: 44,693,1981
| 110406-75-2 |
Physiosol 1-L
| 110406-75-2 |
Physiosol 1-S
| 110406-75-2 |
Physodine A
| 122051-33-6 |
Physodine B
| 122051-34-7 |
Physostigmine
| 57-47-6 |
Physostigmine, methiodide
| 6091-11-8 |
Physostigmine, salicylate (11)
| 57-64-7 |
Physostigmine, tartrate
| 57-64-7 |
1(2H)-Phthalazinone,2-(8-(cyclohexylmethyl)-8-azabicyclo(3.2.1)oct-3-yl)-4-((4-fluorophenyl) methyl)-
| 110406-71-8 |
Phytic acid, hexacopper (II) salt
| 63903-50-4 |
Phytohemagglutinin
| 9008-97-3 |
Phytohemagglutinin, dolichos lablab
| 9008-97-3 |
Phytohemagglutinin, phaseolus lunatus
| 9008-97-3 |
Phytohemagglutinin, pisum sp.
| 9008-97-3 |
Phytol
| 150-86-7 |
Phytolacca acinosa Roxb., extractSUBSTANCE DEFINITION :Plant belonging to the family PhytolacaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 150-86-7 |
Phytolacca americana Linn., root extract
| 150-86-7 |
Phytolacca dodecandra, extract
| 39278-85-8 |
Phytolacca dodecandra L'Herit, extractSUBSTANCE DEFINITION :African plant belonging to the family PhytolaccaceesREFERENCE :JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. IrelandLtd., POB 85, Limerick, Ireland) V.1- 1979-
| 39278-85-8 |
1(2H)-Phthalazinone, 8-amino-4-methyl-2-phenyl-
| 16676-83-8 |
1(2H)-Phthalazinone,2-(8-(3-cyclohexyl-3-oxopropyl)-8-azabicyclo(3.2.1)oct-3-yl)-4- ((4-fluorophenyl)methyl)-,monohydrochloride
| 110406-73-0 |
Phytolacca dodecandra L'Herit, root extractSUBSTANCE DEFINITION :Plant belonging to the family PhytolaccaceesREFERENCE :JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. IrelandLtd., POB 85, Limerick, Ireland) V.1- 1979-
| 110406-73-0 |
PhytonSUBSTANCE DEFINITION :Fungicide containing copperREFERENCE :GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/OMezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-Volume(issue)/page/year: 52(8),25,1987
| 110406-73-0 |
Phyton-27
| 73070-37-8 |
Picea abies (linn.) Karst., extract excluding roots
| 91770-69-3 |
Picea morinda Link., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family PinaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 91770-69-3 |
Picene
| 213-46-7 |
Pichia fermentans, glucan extractSUBSTANCE DEFINITION :A yeast belonging to the Saccharomycetaceae familyREFERENCE :USXXAM United States Patent Document. (U.S. Patent Office, Box 9,Washington, DC 20231)
| 213-46-7 |
Picibanil
| 39325-01-4 |
Picnomon arcana Cass., flower extract
| 39325-01-4 |
Picolinaldehyde, bis(2-chloroethyl)hydrazone
| 7606-04-4 |
1(2H)-Phthalazinone,2-(8-(cyclopropylmethyl)-8-azabicyclo(3.2.1)oct-3-yl)-4- ((4-fluorophenyl)methyl)-, monohydrochloride
| 110406-72-9 |
Picolinaldehyde, 1,6-dihydro-1-methyl-, oxime,hydrochloride
| 57619-29-1 |
Picolinaldehyde, 5-hydroxy-, thiosemicarbazone
| 19494-89-4 |
Picolinaldehyde, oxime
| 873-69-8 |
Picolinaldehyde, thiosemicarbazone
| 3608-75-1 |
Picolinamide, N-(1-adamantyl)-
| 61876-32-2 |
Picolinamide, N-(2-(1-adamantyl)ethyl)-,hydrochloride
| 61876-34-4 |
Picolinamide, N-(p-(1-adamantyl)phenyl)-,hydrochloride
| 61876-33-3 |
Picolinamide, 5-butyl-N-(2-(diethylamino)ethyl)-,hydrochloride
| 66715-48-8 |
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