===================== Product Identification =====================
MSDS NAME:CEENU 2X10 MG BT, PURPLE
NIIN:01-056-4034
MSDS Number: BKYRN
=== Responsible Party ===
Company:BRISTOL-MYERS SQUIBB CO, US PHARM/NITRI
Address:2400 W LLOYD EXPRESSWAY
City:EVANSVILLE
State:IN
ZIP:47721
Info Phone Num:(812) 429-5678
Emergency Phone Num:(812) 429-5678
CAGE:BRIST
=== Contractor Identification ===
Company:BRISTOL-MYERS SQUIBB PHARMACEUTICAL GROUP
Box:191
City:NEW BRUNSWICK
State:NJ
ZIP:08903
Country:US
Phone:908-519-2385
CAGE:BRIST
Company:BRISTOL-MYERS US PHARMACEUTICAL & NUTRITIONAL GP.
Address:2400 W LLOYD EXPY
Box:City:EVANSVILLE
State:IN
ZIP:47721-0001
Country:US
Phone:812-429-5644
CAGE:29398
============= Composition/Information on Ingredients =============
Name:1-(2-CHLOROETHYL)-3-CYCLOHEXYL-1 NITROSOUREA
CAS:13010-47-4
RTECS #:YS4900000
Fraction by Wt: 4.5%
===================== Hazards Identification =====================
LD50 LC50 Mixture:ORAL RAT LD50: 70 MG/KG ACTIVE DRUG
Routes of Entry: Inhalation:NO Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:INGESTION: HEMOTOLOGIC,HEPATIC,
LUNG/KIDNEY TOXICITY. SKIN: ABSORBED, POSSIBLE RASH. EYES:
CONJUNCTIVITIS.
Explanation of Carcinogenicity:SUSPECT HUMAN CARCINOGEN
Effects of Overexposure:INGESTION: HEMOTOLOGIC, HEPATIC, LUNG/KIDNEY
TOXICITY & POTIENTIAL CARCINOGEN. SKIN: ABSORBED, POSSIBLE RASH.
EYES: CONUNCTIVITIS. POTENTIAL CARCINOGEN.
======================= First Aid Measures =======================
Eyes: WASH W/COPIOUS AMOUNTS OF WATER FOR 15 MINS. SKIN: WASH
AFFECTED AREA W/SOAP & WATER. INGESTION/INHALATION: OBTAIN MEDICAL
ATTENTION IN ALL CASES.
===================== Fire Fighting Measures =====================
Extinguishing Media:CO2, DRY CHEMICAL
Fire Fighting Procedures:DOESN'T SUPPORT COMBUSTION.
================== Accidental Release Measures ==================
Spill Release Procedures:PICK UP INTACT CAPSULES. IF CAPSULES ARE
CRUSHED, WIPE SOLIDS W/WET ABSORBENT GAUZE OR TOWELS.
====================== Handling and Storage ======================
Handling and Storage Precautions:AVOID EXCESSIVE HEAT >40F. STORE AT
ROOM TEMPERATURE.
Other Precautions:STAFF WHO IS PREGNANT, BREASTFEEDING OR CONCERNED OF
REPRODUCTIVE ISSUES, CONSULT PHYSICIAN. CONSIDER KEEPING A
PERMANENT REGISTRY OF STAFF WHO ROUTINELY PREPARE/ADMINISTER CEENU.
============= Exposure Controls/Personal Protection =============
Respiratory Protection:NIOSH APPROVED DUST RESPIRATOR, HIGH EFFICIENCY
DUST FILTER OR POWERED AIR-PURIFYING RESPIRATOR IF BSC OR SUITABLE
VENTILATION ISN'T AVAILABLE, & A NUMBER OF CAPSULES ARE TO BE
OPENED.
Ventilation:BIOLOGICAL SAFETY CABINET OR LABORATORY EXHAUST HOOD IF
CAPSULES ARE TO BE OPENED.
Protective Gloves:DISPOSABLE SURGICAL LATEX
Eye Protection:SAFETY GLASSES OR GOGGLES
Other Protective Equipment:PROTECTIVE DISPOSABLE GOWN OF LOW
PERMEABILITY FABRIC W/CLOSED FRONT, LONG SLEEVES & PLASTIC CUFFS.
Work Hygienic Practices:WASH THOROUGHLY BEFORE EATING OR SMOKING.
PRE-PLACEMENT PHYSICAL EXAM RECOMMENDED.
Supplemental Safety and Health
EATING, DRINKING, SMOKING, CHEWING GUM, APPLYING COSMETICS OR STORING
FOOD NEAR PREPARATION AREA SHOULD BE FORBIDDEN. FEDERAL LAW
PROHIBTS DISPENSING W/O PRESCRIPTION.
================== Physical/Chemical Properties ==================
Melt/Freeze Pt:M.P/F.P Text:194F
Solubility in Water:INSOLUBLE
Appearance and Odor:YELLOW POWDER IN CAPSULES.
================= Stability and Reactivity Data =================
Stability Indicator/Materials to Avoid:YES
Stability Condition to Avoid:EXCESSIVE HEAT >40F.
Hazardous Decomposition Products:NONE KNOWN, BUT ASSUME A CARCINOGENIC
POTENTIAL.
==================== Disposal Considerations ====================
Waste Disposal Methods:TREAT PRODUCT & CONTAMINATED MATERIALS AS
HAZARDOUS WASTE. INCINERATION IS RECOMMENDED.
Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.
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