LD50 LC50 Mixture:ORAL LD50(RAT): 2859 MG/KG
Routes of Entry: Inhalation:NO Skin:YES Ingestion:NO
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:OVERDOSAGE OF DOPAMINE HYDROCHLORIDE
MAY CAUSE EXCESSIVE BLOOD PRESSURE ELEVATION. DOPAMINE
HYDROCHLORIDE IS INDICATED FOR THE CORRECTION DUE TO MYOCARDIAL
INFARCTIONS/TRAUMA/ENDOTOXIC SEPTICEMIA/OPEN HEART SURGERY/RENAL
FAILURE/CHRONIC CARDIAC DECOMPENSATION AS IN CONGESTIVE FAILURE.
Explanation of Carcinogenicity:NONE
======================= First Aid Measures =======================
First Aid:OVERDOSAGE OF DOPAMINE HYDROCHLORIDE-REDUCE RATE OF
ADMINISTRATION/TEMPORARILY DISCONTINUE DOPAMINE HYDROCHLORIDE UNTIL
PATIENT'S CONDITION STABILIZES. USE OF THE SHORT-ACTING ALPHA
ADRENERGIC BLOCKIN G AGENT, PHENTOLAMINE, SHOULD BE CONSIDERED.
SKIN: WASH W/MILD SOAP/COPIOUS AMOUNTS OF WATER. EYES: FLUSH
W/COPIOUS AMOUNTS OF WATER. INGESTION: INDUCE VOMITING. OBTAIN
MEDICAL ATTENTION IN ALL CASES.
===================== Fire Fighting Measures =====================
Ventilation:LOCAL VENTILATION ADEQUATE
Protective Gloves:RECOMMENDED
Eye Protection:SAFETY GLASSES
Supplemental Safety and Health
HEALTH HAZ CONT'D: PATIENTS MOST LIKELY TO RESPOND TO DOPAMINE
HYDROCHLORIDE ARE THOSE IN WHOM PHYSIOLOGICAL PARAMETERS SUCH AS
URINE FLOW, MYOCARDIAL FUNCTION & BLOOD PRESSURE & HAVEN'T
UNDERGONE PRO FOUND DETERIORATION.
Evaporation Rate & Reference:(WATER=1): <1
Solubility in Water:MISCIBLE
Appearance and Odor:CLEAR, COLORLESS SOLUTION W/NO ODOR
================= Stability and Reactivity Data =================
Stability Indicator/Materials to Avoid:YES
IRON SALTS, OXIDIZING AGENTS, SODIUM BICARBONATE, ALKALINE SOLUTIONS
Stability Condition to Avoid:LIGHT, TEMPS <59F & >86F.
Waste Disposal Methods:APPROVED CHEMICAL WASTE INCINERATION/APPROVED
AQUEOUS DISCHARGE TO MUNICIPAL/ON-SITE WASTEWATER TREATMENT SYSTEMS
IN ACCORDANCE W/LOCAL, STATE & FEDERAL REGULATIONS.
Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.