=====================  Product Identification  =====================

MSDS NAME:ACETONITRILE 00170, A21RS115
Status Code:A
MSDS Number: CJRHJ
=== Responsible Party ===
Company:FISHER SCIENTIFIC
Address:1 REAGENT LANE
City:FAIRLAWN
State:NJ
ZIP:07410
Country:US
Info Phone Num:201-796-7100
Emergency Phone Num:(800)424-9300
Chemtrec Ind/Phone:(800)424-9300
CAGE:1B464
=== Contractor Identification ===
Company:FISHER SCIENTIFIC CO.  CHEMICAL MFG DIV
Address:1 REAGENT LANE
Box:City:FAIRLAWN
State:NJ
ZIP:07410-2802
Country:US
Phone:201-796-7100
CAGE:1B464

=============  Composition/Information on Ingredients  =============

Name:ACETONITRILE  LD50: (ORAL, RAT) 2730 MG/KG
CAS:75-05-8
RTECS #:AL7700000
= Wt:99.
OSHA PEL:70 MG/M3;40 PPM
ACGIH TLV:67 MG/M3;40 PPM
ACGIH STEL:101 MG/M3;60 PPM
EPA Rpt Qty:5000 LBS
DOT Rpt Qty:5000 LBS

=====================  Hazards Identification  =====================

LD50 LC50 Mixture:SEE INGREDIENT 1
Routes of Entry: Inhalation:YES  Skin:YES  Ingestion:YES
Reports of Carcinogenicity:NTP:NO    IARC:NO	OSHA:NO
Health Hazards Acute and Chronic:EYE: MAY CAUSE MODERATE EYE IRRIT.
    VAPS MAY CAUSE EYE IRRIT. SKIN: MAY BE HARMFUL IF ABSORBED THRU
    SKIN. MAY BE METABOLIZED TO CYANIDE WHICH IN TURN ACTS BY
    INHIBITING CYTOCHROME OXIDASE IMPAIRING CEL LULAR RESPIRATION.
    INGEST: MAY CAUSE IRRIT OF DIGESTIVE TRACT. MAY CAUSE EFTS SIMILAR
    TO THOSE FOR INHAL EXPOS. INHAL: HARMFUL IF INHALED. INHAL OF HIGH
    CONCS MAY CAUSE CNS EFTS CHARACTERIZED BY HDCH,  DIZZ, UNCON &
    COMA. MAY CAUSE LIVER & KIDNEY DMG. VAPS MAY CAUSE DIZZ OR
    SUFFOCATION. MAY CAUSE NAUS, DIZZ & HDCH. INHAL MAY LEAD TO DIZZ,
    WEAK & DROW, LEADING TO STUPOR, UNCON & EVEN DEATH. INHAL MA Y LEAD
    TO	(EFTS OF OVEREXP)
Effects of Overexposure:HLTH HAZ: HEMATEMESIS, CONVULSIONS, CHOCK, COMA
    & POSSIBLE DEATH. CHRONIC: CHRONIC INHAL & INGEST MAY CAUSE EFTS
    SIMILAR TO THOSE OF ACUTE INHAL & INGEST. MAY BE METABOLIZED TO
    CYANIDE WHICH IN TURN A CTS BY INHIBITING CYTOCHROME OXIDASE
    IMPAIRING CELLULAR RESPIRATION. ANIMAL STUDIES HAVE REPORTED THAT
    FETAL EFTS/ABNORMALITIES MAY OCCUR WHEN MATERNAL TOXICITY IS SEEN.

=======================  First Aid Measures  =======================

Eyes: FLUSH  W/PLENTY OF WATER FOR AT LEAST 15 MIN, OCCASNLY
    LIFTING UPPER & LOWER LIDS. GET MED AID IMMED. SKIN: GET MED AID
    IMMED. FLUSH SKIN W/PLENTY OF SOAP & WATER FOR AT LEAST 15 MIN
    WHILE REMOV ING CONTAM CLTHG & SHOES. INGEST: IF VICTIM CONSCIOUS &
    ALERT, GIVE 2-4 CUPFULS OF MILK OR WATER. NEVER GIVE ANYTHING BY
    MOUTH TO UNCON PERSON. GET MED AID IMMED.  INHAL: GET MED AID
    IMMED. REMOVE FRO M EXPOS TO FRESH AIR IMMED. IF BRTHG IS DFCLT,
    GIVE OXYG. NOTES TO MD: EXPOS SHOULD BE TREATED AS CYANIDE
    POISONING. EFTS MAY BE DELAYED. ANTIDOTE: ALWAYS HAVE CYANIDE
    ANTIDOTE KIT ON HAND WHEN WORING  W/CYANIDE CMPDS. GET MED ADVICE
    TO USE.

=====================  Fire Fighting Measures  =====================

Flash Point:=6.C, 42.8F
Autoignition Temp:=524.C, 975.2F
Lower Limits:4.4%
Upper Limits:16.0%
Extinguishing Media:SM FIRES:USE DRY CHEM, CO*2, WATER
    SPRAY/ALCOHOL-RESIST FOAM. USE WATER SPRAY TO COOL FIRE-EXPOS
    CNTNRS. WATER MAY BE INEFFECTIVE. DO NOT USE STRAIGHT STREAMS OF
    WATER. LG (SUPDAT)
Fire Fighting Procedures:USE NIOSH APPROVED SCBA AND FULL PROTECTIVE
    EQUIPMENT . NFPA RATING: HEALTH-2; FLAMMABILITY-3; REACTIVITY-0.
Unusual Fire/Explosion Hazard:CNTNRS CAN BUILD UP PRESS IF EXPOS TO
    HEAT &/OR FIRE. VAPS MAY FORM EXPLO MIX W/AIR. VAPS CAN TRAVEL TO
    IGNIT SOURCE & FLASH BACK. COMBUST GENERATES TOX FUMES. USE WATER
    SPRAY TO KEEP FIRE-EXPOS CNTNR S COOL. FLAM LIQ. VAPS MAY BE
    HVR/AIR. THEY CAN SPREAD ALONG GROUND & COLLECT IN LOW/CONFINED
    AREAS. CNTNRS MAY (SUPDAT)

==================  Accidental Release Measures  ==================

Spill Release Procedures:USE PROPER PERSONAL PROTECTIVE EQUIPMENT.
    AVOID RUNOFF INTO STORM SEWERS AND DITCHES WHICH LEAD TO WATERWAYS.
    REMOVE ALL SOURCES OF IGNITION. ABSORB SPILL USING AN ABSORBENT,
    NON-COMBUSTIBLE MATERIAL  SUCH AS EARTH, SAND OR VERMICULITE. A
    VAPOR SUPPRESSING FOAM MAY BE USED TO REDUCE VAPORS. WATER SPRAY
    MAY REDUCE VAPOR BUT MAY NOT PREVENT IGNITION IN CLOSED SPACES.

======================	Handling and Storage  ======================

Handling and Storage Precautions:KEEP AWAY FROM HEAT, SPKS & FLAME.
    KEEP AWAY FROM SOURCES OF IGNIT. STORE IN TIGHTLY CLOSED CNTNR.
    KEEP FROM CNTCT W/OXIDIZING MATLS. STORE IN COOL, DRY, WELL-VENTD
    AREA AWAY FROM INCOMPAT SUBSTANCES.  WASH THOROUGHLY AFTER HNDLG.
    REMOVE CONTAM CLTHG & WASH BEFORE USE. USE ONLY IN WELL VENTD AREA.
Other Precautions:GROUND & BOND CNTNRS WHEN TRANSFERRING MATL. AVOID
    CNTCT W/EYES, SKIN & CLTHG. EMPTY CNTNRS RETAIN PROD RESIDUE (LIQ
    &/OR VAP) & CAN BE DANGEROUS. KEEP CNTNR TIGHTLY CLSD. AVOID CNTCT
    W/HEAT, SPKS & F LAME. DO NOT INGEST/INHALE. DO NOT PRESSURIZE,
    CUT, WELD, BRAZE, SOLDER, DRILL, GRIND/EXPOSE EMPTY C NTNRS TO
    (SUPDAT)

=============  Exposure Controls/Personal Protection  =============

Respiratory Protection:FOLLOW THE OSHA RESPIRATOR REGULATIONS FOUND IN
    29 CFR 1910.134 OR EUROPEAN STANDARD EN 149. ALWAYS USE A NIOSH OR
    EUROPEAN STANDARD EN 149 APPROVED RESPIRATOR WHEN NECESSARY.
Ventilation:USE ADEQ GEN/LOC EXHST VENT TO KEEP AIRBORNE CONCS BELOW
    PEL. ACETONITRILE: EXPOS LIMS: ACGIH-40PPM; 67 MG/M3; 60PPM STEL;
    101 MG/M3 STEL. NIOSH-20PPM (SUPDAT)
Protective Gloves:IMPERVIOUS GLOVES .
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:ANSI APPROVED EYE WASH AND DELUGE SHOWER .
    WEAR APPROPRIATE PROTECTIVE CLOTHING TO PREVENT SKIN EXPOSURE.
Supplemental Safety and Health
OTHER PRECS:HEAT, SPKS/OPEN FLAME. EXTING MEDIA:FIRES:USE DRY CHEM,
    CO*2, ALCOHOL-RESIST FOAM/WATER SPRAY. COOL CNTNRS W/FLOODING QTYS
    OF WATER UNTIL WELL AFTER FIRE IS OUT. EXPLO HAZ:MAY EXPLODE WHEN 
    HEATED. VENT:TWA; 34MG/M3 TWA; 500PPM IDLH. OSHA-40PPM TWA; 70
    MG/M3 TWA. OSHA VACATED PELS:40PPM TWA; 70MG/M3 TWA.

==================  Physical/Chemical Properties  ==================

Melt/Freeze Pt:=-50.C, -58.F
Decomp Temp:Decomp Text:NOT AVAILABLE
Vapor Pres:73 MM HG
Vapor Density:1.4(AIR=1)
Spec Gravity:0.7810
pH:NOT AVAILABLE
Viscosity:0.36 CP 20 DEG
Solubility in Water:SOLUBLE
Appearance and Odor:CLEAR, COLORLESS LIQUID; SWEETISH ODOR - AROMATIC
    ODOR.

=================  Stability and Reactivity Data  =================

Stability Indicator/Materials to Avoid:YES
CHLORINE FLUORIDE, FLUORINE, 2-CYANO-2-PROPYL NITRATE, DINITROGEN
    TETRAOXIDE, INDIUM, DIPHENYL SULFOXIDE, TRICHLOROSILANE, N-FLUORO
    CMPDS, IRON (III) PERCHLORATE, LANTHANIDE, NITRIC ACID, PERCHLORIC
    ACID, SULFURIC ACID, SUL
Stability Condition to Avoid:STABLE UNDER NORMAL TEMPERATURES AND
    PRESSURES. AVOID INCOMPATIBLE MATERIALS, IGNITION SOURCES.
Hazardous Decomposition Products:HYDROGEN CYANIDE, NITROGEN OXIDES,
    CARBON MONOXIDE, CARBON DIOXIDE.

===================  Toxicological Information	===================

Toxicological Information:CAS #75-05-8, RTECS #AL7700000. LD50/LC50 -
    INHAL, MOUSE: LC50=2693 PPM/1H; INHAL, RABBIT: LC50=2828 PPM/4H;
    INHAL, RAT: LC50=7551 PPM/8H; ORAL, MOUSE: LD50=269 MG/KG; ORAL,
    RABBIT: LD50=50 MG/KG; ORA L, RAT: LD50=2730 MG/KG; SKIN,
    RABBIT:LD50=1250 MG/KG; CARCINOGENICITY - ACGIH: A4 - NOT
    CLASSIFIABLE AS HUMAN CARCIN. EPIDEMIOLOGY - NO INFO AVAIL.
    TETRAGENICITY - EMBRYO OR FETUS: STUNTED FETUS, IHL -HAMSTER
    TCLO=8000 PPM/1H. SPECIFIC DEVELOPMENTAL ABNORMS: MUSCULOSKELETAL,
    ORL-HAMSTER TCLO=300 MG/KG. REPRO EFTS - FERTILITY:
    POST-IMPLANTATION MORTALITY, ORL-HAMSTER TDLO=400 MG/KG &
    IHL-HAMSTER TC LO=5000 PPM/1H. (OTHER INFO)

=====================  Ecological Information  =====================

Ecological:EXOTOXICITY: FATHEAD MINNOW (HARD WATER) TLM=1150 PPM/24H.
    ENVIRONMENTAL FATE: NO INFO REPORTED. PHYSICAL/CHEMICAL: NO INFO
    AVAIL. OTHER: NONE. OTHER INFO: ADVICE IMMED (SHOW LABEL WHERE
    POSS). WGK (W ATER DANGER/PROT) CAS #75-05-8: 2. CANADA: CAS
    #75-05-8 IS LISTED ON CANADA'S DSL/NDSL LIST, HAS A WHMIS
    CLASSIFICATION OF B2, D1B, D2B. IT IS NOT LISTED ON CANADA'S INGRED
    DISCLOSURE LIST. EXPOS LIMS : CAS #75-05-8: OEL-ARAB REPUBLIC OF
    EGYPT:TWA 40 PPM (70 MG/M3); SKIN OEL-AUSTRALIA: TWA 40 PPM (70
    MG/M3); STEL 60 PPM; SKIN OEL-AUSTRIA; TWA 40 PPM (70 MG/M3)
    OEL-BELGIUM:TWA 40 PPM (67 MG/M3); STE L 60 PPM (10 MG/M3);
    (TRANSPORT INFO)

====================  Disposal Considerations  ====================

Waste Disposal Methods:DISPOSE OF IN A MANNER CONSISTENT WITH FEDERAL,
    STATE AND LOCAL REGULATIONS. RCRA D-SERIES MAXIMUM CONCENTRATION OF
    CONTAMINANTS: NONE LISTED. RCRA D-SERIES CHRONIC TOXICITY REFERENCE
    LEVELS: NONE LIS TED. RCRA F-SERIES: NONE LISTED. RCRA P-SERIES:
    NONE LISTED. RCRA U-SERIES: CAS #75-05-8: WASTE #U00 3 (IGNITABLE
    WASTE; TOXIC WASTE).

===================  MSDS Transport Information  ===================

Transport Information:SHIPPING NAME - US DOT: ACETONITRILE; IATA: NO
    INFO AVAIL; RID/ADR: NO INFO AVAIL. IMO: NO INFO AVAIL.
    ACETONITRILE. HAZ CLASS - US DOT: 3; IMO: 3(6.1). UN NUMBER: US
    DOT: UN1648; IMO: UN1648. PACKING  GROUP: US DOT: II; IMO: II.
    ADDNL INFO: IMO: FLASHPOINT 6C. ECOLOGICAL INFO: SKIN
    OEL-DENMARK:TWA 40 PPM (70 MG/M3); STEL 60 PPM (10 MG/M3);
    OEL-FINLAND: TWA 40 PPM (70 MG/M3); STEL 60 PPM (10 MG/M3) ;
    OEL-FRANCE: TWA 50 MG/M3; STEL 100 MG/M3; SKIN JAN9 OEL-THE
    NETHERLANDS: TWA 40 PPM (70 MG/M3) OEL-THE PHILIPPINES: TWA 40 PPM
    (70 MG/M3) OEL-RUSSIA: STEL 10 MG/M3; OEL-SWITZERLAND: TWA 40 PPM
    (70 M G/M3); STEL 80 PPM; (STATE REG INFO)

=====================  Regulatory Information  =====================

SARA Title III Information:CAS #75-05-8: SARA SECTION 302(RQ): FINAL
    RQ=5000 LBS (2270 KG). SECTION 302(TPQ): NONE OF CHEMICALS IN
    PRODUCT HAVE TPQ. SARA CODES: ACUTE, CHRONIC, FLAMMABLE. SECTION
    313: MATERIAL CONTAINS ACETONIT RILE (CAS #75-05-8, 99%) WHICH IS
    SUBJECT TO REPORTING REQS OF SECTION 313 OF SARA TITLE III & 40 CFR
    PART 373.
Federal Regulatory Information:CAS #75-05-8: TSCA: LISTED ON TSCA
    INVENTORY. HLTH & SFTY REPORTING LIST: EFTIVE DATE: OCT 4, 1982;
    SUNSET DATE: OCT 4, 1992. CHEM TEST RULES: NONE OF CHEMS IN PROD
    UNDER CHEM TEST RULE. SECTION 12B:	NONE OF CHEMS LISTED UNDER TSCA
    SECTION 12B. TSCA SIGNIFICANT NEW USE RULE: NONE OF CHEMS IN MATL
    HAVE SNUR UNDER TSCA. CLEAN AIR ACT: LISTED AS HAZ AIR POLLUTANT
    (HAP). MATL DOES NOT CNTN ANY CLASS 1  OR CLASS 2 OZONE DEPLETORS.
    CLEAN WATER ACT: NONE OF CHEMS IN PROD LISTED AS HAZ SUBSTANCES
    UNDER C WA. NONE OF CHEMS LISTED AS PRIORITY OR TOX POLLUTANTS
    UNDER CWA. NONE CONSIDERED HIGHLY HAZ BY OSHA.
    EUROPEAN/INTERNATIONAL  (OTHER INFO)
State Regulatory Information:CAS #75-05-8 CAN BE FOUND ON FOLLOWING
    STATE RIGHT TO KNOW LISTS: CALIFORNIA, NEW JERSEY, FLORIDA,
    PENNSYLVANIA, MINNESOTA, MASSACHUSETTS. CALIFORNIA NO SIGNIFICANT
    RISK LEVEL: NONE OF CHEMS IN THIS P ROD ARE LISTED. TRANSPORT INFO:
    SKIN OEL-TURKEY: TWA 40 PPM (70 MG/M3) OEL-UNITED KINGDOM:TWA 40
    PPM (70 MG/M3); STEL 60 PPM; OEL IN BULGARIA, COLOMBIA, JORDAN,
    KOREA CHECK ACGIH. TLV OEL IN NEW ZEALA ND, SINGAPORE, VIETNAM
    CHECK ACGIH TLV.

=======================  Other Information  =======================

 Disclaimer (provided with this information by the compiling agencies):
 This information is formulated for use by elements of the Department
 of Defense.  The United States of America in no manner whatsoever,
 expressly or implied, warrants this information to be accurate and
 disclaims all liability for its use.  Any person utilizing this
 document should seek competent professional advice to verify and
 assume responsibility for the suitability of this information to their
 particular situation.

*** END OF RECORD ***