Product #: 295582 Name: NITROGEN DIOXIDE, 99.5+%
Material Safety Data Sheet, Valid Dates 11/2002- 1/2003
Printed 01/23/2003 09:46
Page 1
Sigma-Aldrich
3050 Spruce Street
St. Louis, MO 63103, US
Technical Phone: 314 771 5765
Emergency Phone: 314 771 5765
Fax: 800 325 5052
SECTION 1. - - - - - - - - - CHEMICAL IDENTIFICATION- - - - - - - - - -
CATALOG #: 295582
NAME: NITROGEN DIOXIDE, 99.5+%
SECTION 2. - - - - - COMPOSITION/INFORMATION ON INGREDIENTS - - - - - -
CAS #: 10544-72-6
MF: N2O4
EC NO: 234-126-4
SYNONYMS
AZOTE (FRENCH) * AZOTO (ITALIAN) * NITRITO * NITROGEN DIOXIDE (ACGIH:
OSHA) * NITROGEN PEROXIDE * RCRA WASTE NUMBER P078 * STICKSTOFFDIOXID
(GERMAN) * STIKSTOFDIOXYDE (DUTCH) *
SECTION 3. - - - - - - - - - - HAZARDS IDENTIFICATION - - - - - - - - -
LABEL PRECAUTIONARY STATEMENTS
OXIDIZING
HIGHLY TOXIC (USA)
TOXIC (EU)
CONTACT WITH COMBUSTIBLE MATERIAL MAY CAUSE FIRE.
TOXIC BY INHALATION.
CAUSES BURNS.
DANGER: POISONOUS, CORROSIVE AND OXIDIZING LIQUID AND GAS UNDER
PRESSURE.
IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF
WATER AND SEEK MEDICAL ADVICE.
WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE
PROTECTION.
IN CASE OF INSUFFICIENT VENTILATION, WEAR SUITABLE
RESPIRATORY EQUIPMENT.
IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).
USE WITH EQUIPMENT RATED FOR CYLINDER PRESSURE, AND OF COMPATIBLE
MATERIALS OF CONSTRUCTION. CLOSE VALVE WHEN NOT IN USE AND WHEN EMPTY.
MAKE SURE CYLINDER IS PROPERLY SECURED WHEN IN USE OR STORED.
Product #: 295582 Name: NITROGEN DIOXIDE, 99.5+%
Material Safety Data Sheet, Valid Dates 11/2002- 1/2003
Printed 01/23/2003 09:46
Page 2
SECTION 4. - - - - - - - - - - FIRST-AID MEASURES- - - - - - - - - - -
IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES OR SKIN WITH COPIOUS
AMOUNTS OF WATER FOR AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED
CLOTHING AND SHOES.
KEEP UNDER MEDICAL OBSERVATION.
IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL
RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
SECTION 5. - - - - - - - - - FIRE FIGHTING MEASURES - - - - - - - - - -
EXTINGUISHING MEDIA
USE WATER SPRAY OR FOG NOZZLE TO KEEP CYLINDER COOL. MOVE CYLINDER
AWAY FROM FIRE IF THERE IS NO RISK.
SPECIAL FIREFIGHTING PROCEDURES
WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO
PREVENT CONTACT WITH SKIN AND EYES.
UNUSUAL FIRE AND EXPLOSIONS HAZARDS
CONTACT WITH OTHER MATERIAL MAY CAUSE FIRE.
EMITS TOXIC FUMES UNDER FIRE CONDITIONS.
VIGOROUSLY SUPPORTS COMBUSTION.
SECTION 6. - - - - - - - - ACCIDENTAL RELEASE MEASURES- - - - - - - - -
EVACUATE AREA AND KEEP PERSONNEL UPWIND.
SHUT OFF ALL SOURCES OF IGNITION.
SHUT OFF LEAK IF THERE IS NO RISK.
SECTION 7. - - - - - - - - - - HANDLING AND STORAGE- - - - - - - - - - -
REFER TO SECTION 8.
SECTION 8. - - - - - - EXPOSURE CONTROLS/PERSONAL PROTECTION- - - - - -
NIOSH/MSHA-APPROVED RESPIRATOR IN NONVENTILATED AREAS AND/OR FOR
EXPOSURE ABOVE THE ACGIH TLV.
RUBBER GLOVES.
CHEMICAL SAFETY GOGGLES.
USE ONLY IN A CHEMICAL FUME HOOD.
SAFETY SHOWER AND EYE BATH.
AVOID CONTACT AND INHALATION.
AVOID PROLONGED OR REPEATED EXPOSURE.
WASH THOROUGHLY AFTER HANDLING.
DISCARD CONTAMINATED CLOTHING AND SHOES.
POISON
CORROSIVE.
CYLINDER TEMPERATURE SHOULD NOT EXCEED 125 F(52 C).
KEEP AWAY FROM COMBUSTIBLE MATERIALS, HEAT, SPARKS, AND OPEN FLAME.
SECTION 9. - - - - - - - PHYSICAL AND CHEMICAL PROPERTIES - - - - - - -
APPEARANCE AND ODOR
RED-BROWN GAS
PHYSICAL PROPERTIES
BOILING POINT: 21 C
MELTING POINT: -11 C
VAPOR PRESSURE: 14.33PSI 20 C 61.45PSI 55 C
SPECIFIC GRAVITY: 2.620
VAPOR DENSITY: 1.58 @ 21 C
SWISS POISON CLASS: 2
SECTION 10. - - - - - - - - -STABILITY AND REACTIVITY - - - - - - - - -
INCOMPATIBILITIES
ALCOHOLS
COPPER, COPPER ALLOYS
PHOSPHORUS
AMMONIA
SECTION 11. - - - - - - - - - TOXICOLOGICAL INFORMATION - - - - - - - -
ACUTE EFFECTS
INHALATION OF VAPORS MAY CAUSE RHINITIS, PHARYNGITIS, CYANOSIS,
RESPIRATORY ARREST, COMA, UNCONSCIOUSNESS AND DEATH. CHRONIC EFFECTS:
WEIGHT LOSS, PERSISTENT LOW BLOOD PRESSURE, LOSS OF SENSE OF SMELL,
NEUROLOGIC SEQUELAE SUCH AS AMNESIA, INTENTION TREMOR, NEURASTHENIA,
DISTURBANCE OF EQUILIBRIUM OR MORE SERIOUS BRAIN STEM AND CORTICAL
DAMAGE.
Product #: 295582 Name: NITROGEN DIOXIDE, 99.5+%
Material Safety Data Sheet, Valid Dates 11/2002- 1/2003
Printed 01/23/2003 09:46
Page 3
MATERIAL IS EXTREMELY DESTRUCTIVE TO TISSUE OF THE MUCOUS MEMBRANES
AND UPPER RESPIRATORY TRACT, EYES AND SKIN.
INHALATION MAY RESULT IN SPASM, INFLAMMATION AND EDEMA OF THE
LARYNX AND BRONCHI, CHEMICAL PNEUMONITIS AND PULMONARY EDEMA.
SYMPTOMS OF EXPOSURE MAY INCLUDE BURNING SENSATION, COUGHING,
WHEEZING, LARYNGITIS, SHORTNESS OF BREATH, HEADACHE, NAUSEA AND
VOMITING.
MAY BE FATAL IF INHALED, SWALLOWED, OR ABSORBED THROUGH SKIN.
RTECS #: QW9800000
NITROGEN DIOXIDE
TOXICITY DATA
IHL-HMN LCLO:200 PPM/1M AOHYA3 17,159,1974
IHL-RAT LC50:88 PPM/4H AMIHBC 10,418,1954
IHL-MUS LC50:1000 PPM/10M JCTODH 4,246,1977
IHL-RBT LC50:315 PPM/15M AIHAAP 23,457,1962
IHL-GPG LC50:30 PPM/1H AEHLAU 10,220,1965
TARGET ORGAN DATA
SENSE ORGANS AND SPECIAL SENSES (CONJUNCTIVA IRRITATION)
BEHAVIORAL (CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD)
BEHAVIORAL (CHANGE IN MOTOR ACTIVITY)
LUNGS, THORAX OR RESPIRATION (CHANGE IN TRACHEA OR BRONCHI)
LUNGS, THORAX OR RESPIRATION (CHANGES IN PULMONARY VASCULAR RESISTANCE)
LUNGS, THORAX OR RESPIRATION (CHRONIC PULMONARY EDEMA OR CONGESTION)
LUNGS, THORAX OR RESPIRATION (COUGH)
LUNGS, THORAX OR RESPIRATION (DYSPNAE)
LUNGS, THORAX OR RESPIRATION (RESPIRATORY DEPRESSION)
LUNGS, THORAX OR RESPIRATION (RESPIRATORY STIMULATION)
LUNGS, THORAX OR RESPIRATION (OTHER CHANGES)
BLOOD (METHEMOGLOBINEMIA-CARBOXHEMOGLOBINEMIA)
MATERNAL EFFECTS (MENSTRUAL CYLCE CHANGES OR DISORDERS)
EFFECTS ON FERTILITY (LITTER SIZE)
EFFECTS ON EMBRYO OR FETUS (FETOTOXICITY)
EFFECTS ON EMBRYO OR FETUS (FETAL DEATH)
EFFECTS ON NEWBORN (GROWTH STATISTICS)
EFFECTS ON NEWBORN (BEHAVIORAL)
ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES
(RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR
COMPLETE INFORMATION.
SECTION 12. - - - - - - - - - ECOLOGICAL INFORMATION - - - - - - - - - -
DATA NOT YET AVAILABLE.
SECTION 13. - - - - - - - - - DISPOSAL CONSIDERATIONS - - - - - - - - -
CAUTION: NO-RETURN CYLINDER. DO NOT REUSE. EMPTY CYLINDER WILL CONTAIN
HAZARDOUS RESIDUE. FOLLOW PROPER DISPOSAL TECHNIQUES.
OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS.
SECTION 14. - - - - - - - - - - TRANSPORT INFORMATION - - - - - - - - -
CONTACT ALDRICH CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION.
SECTION 15. - - - - - - - - - REGULATORY INFORMATION - - - - - - - - - -
EUROPEAN INFORMATION
EC INDEX NO: 007-002-00-0
OXIDIZING
TOXIC
R 26
VERY TOXIC BY INHALATION.
R 34
CAUSES BURNS.
S9
KEEP CONTAINER IN A WELL-VENTILATED PLACE.
S 26
IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF
WATER AND SEEK MEDICAL ADVICE.
S 28
AFTER CONTACT WITH SKIN, WASH IMMEDIATELY WITH PLENTY OF SOAP SUDS.
S 36/37/39
Product #: 295582 Name: NITROGEN DIOXIDE, 99.5+%
Material Safety Data Sheet, Valid Dates 11/2002- 1/2003
Printed 01/23/2003 09:46
Page 4
WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE
PROTECTION.
S 45
IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).
REVIEWS, STANDARDS, AND REGULATIONS
OEL=MAK
ACGIH TLV-NOT CLASSIFIABLE AS A HUMAN CARCINOGEN DTLVS* TLV/BEI,1999
ACGIH TLV-STEL 5 PPM DTLVS* TLV/BEI,1999
ACGIH TLV-TWA 3 PPM DTLVS* TLV/BEI,1999
MSHA STANDARD:AIR-CL 5 PPM (9 MG/M3)
DTLVS* 3,185,1971
OSHA PEL (GEN INDU):CL 5 PPM (9 MG/M3)
CFRGBR 29,1910.1000,1994
OSHA PEL (CONSTRUC):CL 5 PPM (9 MG/M3)
CFRGBR 29,1926.55,1994
OSHA PEL (SHIPYARD):CL 5 PPM (9 MG/M3)
CFRGBR 29,1915.1000,1993
OSHA PEL (FED CONT):CL 5 PPM (9 MG/M3)
CFRGBR 41,50-204.50,1994
OEL-ARAB REPUBLIC OF EGYPT: TWA 3 PPM (6 MG/M3), JAN1993
OEL-AUSTRIA: MAK 3 PPM (6 MG/M3), JAN1999
OEL-DENMARK: TWA 3 99M (5.6 MG/M3), JAN1999
OEL-FINLAND: TWA 3 PPM (6 MG/M3), STEL 6 PPM (12 MG/M3), JAN1999
OEL-FRANCE: VLE 3 PPM (6 MG/M3), JAN1999
OEL-GERMANY: MAK 5 PPM (9 MG/M3), JAN1999
OEL-JAPAN: OEL PENDING, JAN1999
OEL-THE NETHERLANDS: MAC-TGG 2 PPM (4 MG/M3), JAN1999
OEL-NORWAY: TWA 2 PPM (3.6 MG/M3), JAN1999
OEL-THE PHILIPPINES: TWA 5 PPM (9 MG/M3), JAN1993
OEL-POLAND: MAC(TWA) 5 MG/M3, MAC(STEL) 10 MG/M3, JAN1999
OEL-SWEDEN: NGV 2 PPM (4 MG/M3), TGV 5 PPM (13 MG/M3), JAN1999
OEL-SWITZERLAND: MAK-W 3 PPM (6 MG/M3), KZG-W 6 PPM (12 MG/M3), JAN1999
OEL-THAILAND: TWA 5 PPM (9 MG/M3), JAN1993
OEL-TURKEY: TWA 5 PPM (9 MG/M3), JAN1993
OEL-UNITED KINGDOM: TWA 3 PPM (5.7 MG/M3), STEL 5 PPM (9.6 MG/M3),
SEP2000
OEL IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA CHECK ACGIH TLV;
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM CHECK ACGIH TLV
NIOSH REL TO NITROGEN DIOXIDE-AIR:STEL 1 PPM
NIOSH* DHHS #92-100,1992
NOHS 1974: HZD 50870; NIS 16; TNF 424; NOS 19; TNE 11419
NOES 1983: HZD 50870; NIS 5; TNF 94; NOS 24; TNE 18737; TFE 1773
EPA TSCA SECTION 8(B) CHEMICAL INVENTORY
EPA TSCA SECTION 8(D) UNPUBLISHED HEALTH/SAFETY STUDIES
ON EPA IRIS DATABASE
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH ANALYTICAL METHOD, 1994: NITRIC OXIDE AND NITROGEN DIOXIDE, 6014
OSHA ANALYTICAL METHOD #ID-109
OSHA ANALYTICAL METHOD #ID-182
SECTION 16. - - - - - - - - - - OTHER INFORMATION- - - - - - - - - - - -
THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO
BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA, ALDRICH,
FLUKA SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING
OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR
PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE.
COPYRIGHT 2001 SIGMA-ALDRICH CO.
LICENSE GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY
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