tL/L6/2006 TELT 0:21 ooe
1 FAN @
r#;/ /c-RC
w \3-0 lls'Jcttt1
MSDS- PreservCytt $olution
Product
tdentifisation'
W
TradsNarne/Chemlcal
Famlly/$ynonymst Methanol-water
solution
presarvative
solution
FroductDescrlptlon: A methanol
based,
br.ffered
transport elldepreparatlon.
ProductU$G: A preeervatlvE during
solution support
to and
oells
Manufacturur Cytyc Corporation
g5 sr,rranson
Road
Boxborough, Massachusefte71I
01
USA
Talephone: 800-442-9892
TELEPHONE NUMBERS: For Health/Traneportation/Chemical
EMERGENCY $pllls
(Multlllngual
(24hourea day and 7 deysa week) eapabilities free callr accepted)
and
UnitedStatee:
(800)42+9300
Gontinental
+(703)
Outslde continentel
of United
States: 5n-3887
2. COMPOSITION/INFORMATION INGREdIENTS
ON
wt. %
Comoonent GASReqlstrvf
Methanol 67-5St 30-60
n82-13-5
Water 40-70
3. HAZARDS
IDENTIFICATION:
EMERGENCY Materlal a clearflammable llquld.Inhalatlon vaporsmaycausanonspeclflcdiscomfort
of
ls
effsctsand possibleblindneee.Swallowing
OVERVIEW: (nausea, aa
wlth anesthetic
woaknass), drowslness
little as 4 ouncer ('lf B ml) maycaure bllndne* snd In adremecrael deeth.
PotentlrlHeelthEfrectg.
lnhalation: Maycausedepresslon cEntral
of neffoussplem resulting naus鈧琣,
in weakness,
drowsiness
and
bllndneee.
PoBsibty
EyeGontasl transiant
Maycause irritation.
in
$kln Contacfi Maycauseinltation thrbugh skinresufting
and/or
dermatltls.Materlal beabsorbed
may the
simllar Ingestlon inhalation.
to
effects or
lngestionr Maycauseintoxication. naueea, dizzinees.
and Maydamage
neruous
systemdepregsion,
Cerrbal
liver.
kidneys ngrvous
and systam. cause
May blindness
and/or
death.
TargetOrgans: Liver,
kidnela, cental neruous
and system-
Preparation July,2002
Dat6 Page I ol9 _
CYTYC 85093401Rev,G.
PiN
LL/L6/2006 THU 10;21 FAX Eoor
6
*
MSDS PrcservGyt Solution
Medical
Conditions Individuels praexisting
with (eyes) livermayhaveincreeser
disaaees theretina
of or
Aggravatad Exposure: susceptibility toxiciiy lowerlevels succgssiv鈧?
by at
to of (repeatsd
exposure exposures).
Chronlc: Llquld vapor penetrate andmuoous
can
and skin membranes^ cauge
Mey chronic
liver,
kidney
or
nervous
systemdisorders.
4. FIRSTAID MEASURE$:
Inhalatlon: patient freshair.lf symptoffi$ intoxlcation vislonproblems apparent,
Remove to get
are
of or
immadlate
medicalaid-
EyeGontac{: lmmediately wiihclsanweter at laaEt minutes. madical
flush for 15 Get aid.
SkinGontactr Remove and
contiaminated
clothing shoe$.Fluehaffected
areawlth@pious of
amounts water.
lf irrilation otherEymptortts present, immediate
get
or ere medical
asslEtanc鈧?.
Ingeetion: Do Not lnduceVomltlng.
Givaoneortwoglasses water getimmediab
of and eid.
madtcal
Notes Physiclan: Treat CNSdepression possible
to for and renalfailure.
5. FIREFIGHTINGMEASURES;
Flaehpolnt Method:
and 80oF (26.5oC)Closed
cup
Autoignltlon
Temparature:725 F (385oC)
Flammable
Limits: LEL-6.7UEL-36 (basad methanolcomponent)
on
GeneralHazard: Flammeble
materiel.
Heated
material
mayformtoxicand/or
explosive
vapors.
FireFightingInetruc,tlona: Wearfull turnoutgearwithself-contained apparatus. matarlal notinvolved
breathing lf is
Infire,aftempt coolwithwateror remove
to fom area. FLAME lN
INVISIBLE
DAYLIGHT.
gearw'tth
Flrs FlghtlngEqulpment: Wearfull turnout self-conteined
breathlng
apparatue.
- C02- Yes
-
Extlngulehlng
Madia; Foam Yes Foam Yes
Alcohol DryChemical-Yes
- WaterFog
-
Water Yes Other
Hezardoue
Gombustiorr
Productr: Monoxide Carbon
and Oloxlde
Carbon
Healfir- 1
NFPA Hazard Rating: 0=lnsignifioant
-
(NationalFire Protec{ion 1=Slight
Flammabillty 3
-
Association) Reactlvlty 0 2=Moderate
-
Information None 3=High
Special
4=Extreme
*=No
U=Unknown lnformatlon
$pociallnformatlon: None
CYTVC 6s0s3-001
P/N Page of 5
Preparation July,
Date 2002 2
LL/L6/2008 THLT 0:22 ool
1 FAX @
MSDS- PreservCytt Solution
O ,. ACCIDENTAL
RELEASE
MEA*URES:
Land$plll Prevent runofffromenteringwaterwala.Dykelargespillswithclay. Absorb
smallspiltswithclayor kitty
litter- Forspillsin oxoeas 50 gallons, licensed
of HAa/VOPER
contaot responders.
WaterSpill: guidellnes regulations.
Followlocal,
state Foderal
and and
FollowLocal, Provinclal, Federal
State, Guidelines allspllls.
and for
7. HANDLINGAND $TOMGE:
llandling: KEEP OUTOFTHEREACH CHILDREN. personat
protecuve
Wearrscommendod
OF equipmant
and
avoidcontact skinandeyes.
with
Storage: Storeawayfromexceeeive andsourcrsof ignition.Keep cloeed protEct
hoat containars and fromdamage.
aample: - 86oF (18- 300C)
Temperatures:
Storage 59
Withoutcytologic
weel$:39- 99oF (4 - 37oC)
Wlthcytologic
samples, up to three
for
8. EXPOSURE
CONTROLSPERSONAL
/ PROTECTIVE
EQUIPMENT:
Engineering
Controls; Supply
exhaust ventilalion keepvapot
and/or to threshold value.
levels llmlt
below
Resplrator: Whereenglneerlng controls notadequale, apprwedNIOSH
aro respirators supptied
use or
air respirators.
Protoc'tlveGlothlng: Chemically gloves eyapmtecllon.
resistant and
Llmltsfor
Ingredient OSHAPEL ACGIH
TtW
200ppm-TWA
Methanol 200PP61-TWA
250ppm- STEL
Skin
TWA- I hr - -
Ganada Alberta,BritighGolumhia,Nerv Ganeda Sarkatchewan
-
STEL 15mlnuta Erun*wlclr.Menltoba,
Ontrrlo,
Quebec. Yukon
and
200ppm-TWA 262mg/mlTWA
250 ppm- $TEL 328mg/m'STEL
Skln
9. PHYSICAL
ANDCHEMICAL
PROFERflE$:
VaporPrs*eurc mm/Hg: 127 clesr,thin
Appearance:
$pecific Gravlty(Waterl): 0.92 Phyalcal$tate: liquid
SolubllltyIn Watet*.
complete VaporDendty(Airr,l):1.1
Freezing Poim(oFFC): estabtished.
not Volatlleby Volume;> 99
Pers鈧琻t
Evaporation Rata(EuAc=l); > 1 pH: Notapplicable
Vlscoslty:Notdetermtned Odor:Alcoholtype odor
BoitinseointfFPC); 148/er.5
page3 of S
GYTYC.|A859-9.39..91 G.
Rev. Dsre
,Preparation July,2002
_
L L / L 6 / 2 0 0 6 T f f t T1 0 ; 2 2 oos
FAX @
o
-
MSDS PrsseruCyt $olution
10. $TABILITY
ANDREACTIVITY:
GeneralStabllity: Stable
Incompatible
Materiale Conditlons Avoid:
And To product)
Strong (Maylgnite
oxidlzers.
Hazardous
Decornposition
Products; monoxide carbon
Carbon and dioxide
Haeardous
Polymerlration: Willnotoccur.
11. TOXICOLOGICAL
INFORMATION:
Eormelhanol: ppmi4H
Product Inhalation
LC50Rat 64000
nottestedas a mixture: OralLD50Rat:5628me/kg
OralLDS0 7300mglkg
Mouee:
DermalLDS0Rabbih15800 mg/kS
12. ECOLOGICALINFORMATION:
Material verylowaquatlc
has trcxlclty.
prometas
(fathead Zg,4gtlffihr, (ZE-2e
minnows) dap o}d)
lq{-Pl1鈧琫|raleg
(30
EC50 mirr) Photobacteriumphosphoreum: mg/L
51,000-0?0,000
13. DISPOSAL
CONSIDERATION:
R9RAHazardous
Wastalf Dlacarded?
Yas. lf ro, RCRA numbsr:0001,lgnttable
lD waete,
14. TRANSPOIITA-fl INFORMATION (Departrnent Tnnsportation)
ON : DOT of
US DOT
Proper$hipFlnoname: Flarnmable
liquids,
n.o.s.{Methanol}
Huerd Glaes: 3
ldentification Number: uN1993
Packlng Group: ill
CYTYCPiN
11116/2008 E oos
THti 19;22 FAX
MSDS- PreservCyt6 Solution
15. REGULATORY
INFORMATION;
T$CA(Toxlc$ubetances listed TSGAinvantory.
ControlAct): All ingredients on
kg) NoTPQestablished methanol
5,000 (2,268
CERCLA: RQfor mathenol- lbs. for
$ARAEll $tatua: lmmediate, hazard
flra
list-
$ARA313: Methanof listad the313Toxic
ls on Pollutant
reportifig
$tate lssues: Notllsted Celifomla
for Proposition
65
All lngredients listed thechemical
are on inventories thefollowing
counfies:
ForeignChemlcal
lnvantorles: of
(DSL)
Canada
Japan
Unlon
Eurooean
Auetralia
product.
$tatus(Ganada): A oontrolled 82:DlBlD2A
WHMIS Classiflcation:
Thi$product beEn ctiteria the Contoolled
of
classlfled accordance hazard
In wlth
has
byttu Contolled
Regulations theMSDS contains
alttheinformationr鈧琿uirod
Produob and
ProductsRegulations.
16. OTHERINFORMATIOH:
CurrantlasueDate: Ji.rly,2002
lssuaDetel Macch,2002
Prevloua
values.
exposure
slarity.Mditionof non-US
M$0S; formatandrevision textto improve
of
NEw
Changesto
OtherInformation: Nona
ls
addltionalresearch
MSDS,
datawas contained manufec'ture/s
In
InformationNote: Whersno coffeapondlng
lT
MATERIAL MAYNOTBE
fequiredand avellableupon request.THEINFORMATION RELATES THISSPECIFIC
TO
MATERIALS IN AhIYPROCESS. IS IT
OR
W|THANYOTHER
VALIDFORTI{I$ II'ATERIAL USEDII{ COMBINATION
IF
ONESELF TOTI{ESUITABILITY GOMPLETENES$ THIS OF
A},ID
AS
RESPONSIBILITYTO SATISFV
THEUSER'S
INFORMATION HISORHEROWNPARTICULAR USE.
FOR
|