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Material Safety Data Sheet
HYGROMYCIN B
1: Chemical Product and Company Identification
Product Name: HYGROMYCIN B
Contact information:
Catalog Code: 762047, 762049, 762050, 762051, 762053
bioWORLD
4150 Tuller Rd
CAS#: 31282-04-9
Suite 228, Dublin, OH 43017, USA
RTECS: WK2130000
For information, call: 614-792-8680
Fax Number: 614-792-8685
TSCA: TSCA 8(b) inventory : No products were found.
Order Online:www.bio-world.com
CI#: Not available.
E-mail : save@bio-world.com
Synonym: Antihelmycin; Hydromycin B; Hygromix 2.4; Hygromix-
In case of a chemical emergency, contact local
8; Hygromycin B; Hygrovetine.
hospital.
Chemical Name: Hygromycin B
For non-emergency assistance,call: 1-800-860-9729
Chemical Formula: C20H37N3O13
2: Composition and Information on Ingredients
Composition:
Name CAS# % by Weight
HYGROMYCIN B 31282-04-9 100%
Toxicological Data on Ingredients:
LC50 (Inhalation, Rat): 2220 ug/m3/4H
LC50 (Inhalation, Rat): 2.2 mg/m3
LD50 (Oral, Mouse): 46000 units/kg
LD50 (Oral, Mouse): 46 mg/kg
LD50 (Oral, Rat): 13 mg/kg
3: Hazards Identification
Potential Acute Health Effects: Highly Toxic (USA) Very Toxic (EU).A potent selection antibiotic. Very toxic by
inhalation, in contact with skin and if swallowed.May cause sensitization by inhalation and skin contact. Risk of serious
damage to eyes.
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Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: Not available.
MUTAGENIC EFFECTS: Mutation in bacteria.
TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available.
4: First Aid Measures
Eye Contact: In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate
flushing by separating the eyelids with fingers. Call a physician.
Skin Contact: In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated
clothing and shoes. Call a physician.
Serious Skin Contact: Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek
medical attention.
Inhalation: If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
Serious Inhalation: Not available.
Ingestion: If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.
Serious Ingestion: Not available.
5: Fire and Explosion Data
Flammability of the Product: Nonflammable.
Auto-Ignition Temperature: Not available.
Flash Points: Not available.
Flammable Limits: Not available.
Product of Combustion: Nitrogen oxides, carbon monoxide, carbon dioxide.
Fire Hazards in Presence of Various Substances: Not available.
Explosion Hazards in Presence of Various Substances:
Not available.
Fire Fighting Media and Instructions:
SMALL FIRE: Dry chemical powder.
LARGE FIRE: Water spray. Carbon dioxide, dry chemical powder, or appropriate foam.
Special Remarks on Fire Hazards: Not available.
Special Remarks on Explosion Hazards: Not available.
6: Accidental Release Measures
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Small Spill: Eliminate all ignition sources. Absorb and/or contain spill with inert materials (e.g., sand, vermiculite). Then
place in appropriate container.
Large Spill: For large spills, use water spray to disperse vapors, flush spill area. Prevent runoff from entering waterways or
sewers.
7: Handling and Storage
Precautions: Use only in area provided with appropriate exhaust ventilation.Do not breathe dust. Do not get in eyes, on
skin, on clothing. Avoid prolonged or repeated exposure.
Storage: Keep tightly closed. Store at 2-8掳C.
8: Exposure Controls/Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety
shower. Use adequate ventilation to keep airborne concentrations low.
Personal Protection: Respiratory: Government approved respirator.
Hand: Compatible chemical-resistant gloves.
Eye: Chemical safety goggles.
Personal Protection in Case of a Large Spill: Safety goggles. Lab coat. Dust respirator. Gloves.
Exposure Limits: Not available.
9: Physical and Chemical Properties
Physical State and Appearance: Solid powder.
Odor: Not available.
Taste: Not available.
Molecular Weight: 527.5 g/mole
Color: Light beige .
pH(1% soln/water): Not available.
Boiling Point: 100潞C
Melting Point: Not available.
Critical Temperature: Not available.
Specific Gravity: Not available.
Vapour Pressure: Not available.
Vapor Density: Not available.
Volatility: Not available.
Odor Threshold: Not available.
Water/Oil Dist. Coeff: Not available.
Ionicity (in Water): Not available.
Dispersion Properties: Not available.
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Solubility: Soluble.
10: Stability and Reactivity Data
Stability: Stable.
Instability Temperature: Not available.
Conditions of Instability: Excess heat.
Incompatibility with various substances: Strong oxidising agents.
Corrosivity: Not available.
Special Remarks on Reactivity: Not available.
Special Remarks on Corrosivity: Not available.
Polymerization: Has not been reported.
11:Toxicological Information
Routes of Entry: Skin contact. Eye contact. Ingestion. Inhalation.
Toxicity to Animals:
LD50 (Dermal, Guinea pig): 55 mg/kg
LC50 (Inhalation, Rat): 2220 ug/m3/4H
LC50 (Inhalation, Rat): 2.2 mg/m3
LD50 (Oral, Mouse): 46000 units/kg
LD50 (Oral, Mouse): 46 mg/kg
LD50 (Oral, Rat): 13 mg/kg
LD50 (Skin, Rabbit): 130-250 mg/kg
Chronic Effects on Humans: Not available.
Other Toxic Effects on Humans: Skin Contact: Causes skin irritation.
Skin Absorption: May be fatal if absorbed through skin.
Eye Contact: Causes severe eye irritation.
Inhalation: May be fatal if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
Ingestion: May be fatal if swallowed.
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans: Chronic exposure may cause nausea and vomiting, higher exposure
causes unconsciousness.
Special Remarks on other Toxic Effects on Humans: Not available.
12: Ecological Information
Ecotoxicity: Not available.
BOD5 and COD: Not available.
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Product of Biodegradation: Not available.
Toxicity of the Products of Biodegradation: Not available.
Special Remarks on the Products of Biodegradation: Not available.
13: Disposal Considerations
Waste Disposal: Waste disposal must be in accordance with appropriate Federal, State, and local regulations. This
product, if unaltered by use, may be disposed of by treatment at a permitted facility or as advised by your local hazardous
waste regulatory authority. Residue from fires extinguished with this material may be hazardous.
14: Transport Information
DOT Classification: Class: 6.1
Identification: Toxins, from living sources.
UN#: 3172
Packing Group: I
Special Provisions for Transport: Not available.
15: Other Regulatory Information
Federal and State Regulations: TSCA 8(b) inventory : No products were found.
Other Regulations: European Labeling in Accordance with EC Directives
Hazard Symbols: T+
Risk Phrases:
R 26/27/28 Very toxic by inhalation, in contact with skin and if swallowed.
R 36/37/38 Irritating to eyes, respiratory system and skin.
R 42/43 May cause sensitization by inhalation and skin contact.
R 48 Danger of serious damage to health by prolonged exposure.
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection.
S 46 If swallowed, seek medical advice immediately and show this container or label.
Other Classifications:
WHMIS(Canada): Not available.
DSCL(EEC): Not available.
HMIS(U.S.A):
Health Hazard: 4
Fire Hazard: 0
Reactivity: 0
Personal Protection:
National Fire Protection Association (U.S.A):
Health: 4
5
Flammability: 0
Reactivity: 0
Specific hazard:
Protective Equipment: Gloves. Lab coat. Dust respirator. Safety goggles.
16: Other Information
References: Not available.
Other Special Considerations: Not available.
Created: 23/06/2006 11:58:17 AM
Last Updated: 16/10/2006 3:06:50 PM
Disclaimer
This product is offered by bioWORLD for research, laboratory or further manufacturing use. Not for human use or
consumption.
The information above is believed to be accurate and represents the best information currently available to us. However,we
make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we
assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the
information for their particular purposes.In no event shall Bio-World.com be liable for any claims, losses, or damages of any
third party or for lost profits or any special, indirect,incidental,consequential or exemplary damages, howsoever arising,
even if Bio-World.com has been advised of the possibility of such damages.
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