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Material Safety Data Sheet
TETRACYCLINE HYDROCHLORIDE
1: Chemical Product and Company Identification
Product Name: TETRACYCLINE HYDROCHLORIDE
Catalog Code: 762087, 762089
CAS#: 64-75-5
Contact information:
RTECS: QI9100000
bioWORLD
4150 Tuller Rd
TSCA: TSCA 8(b) inventory : Tetracycline Hydrochloride
Suite 228, Dublin, OH 43017, USA
CI#: Not available.
For information, call: 614-792-8680
Fax Number: 614-792-8685
Synonym: Achromycin hydrochloride; ALA TET; Amycin,
Order Online:www.bio-world.com
Hydrochloride; Artomycin; Bristacycline; Cancycline-250;
Cefracycline tablets; Cyclopar; Diacycine; Dumocyclin;
E-mail : save@bio-world.com
Hostacycline; Medamycin; Mephacyclin; Neocycline B; Panmycin
hydrochloride; Partrex; Polycycline hydrochloride; Polyotic
Ointment; Quadracycline; Quatrex; Remicyclin; Ricycline; In case of a chemical emergency, contact local
Sanclomycine; Steclin; Subamycin; Sumycin; Supramycin; Tefilin; hospital.
Teline; Telotrex; Tetrabid; Tetrablet; Tetracaps; Tetrachel;
Tetracompren; Tetracycline chlorohydrate; Tetracycline For non-emergency assistance,call: 1-800-860-9729
Hydrochloride; Tetra-D; Tetrosol; Topicycline; Triphacyclin; Unicin;
Unimycin; Vetquamycin-324
Chemical Name: Tetracycline Hydrochloride
Chemical Formula: C22H24N2O8路HCl
2: Composition and Information on Ingredients
Composition:
Name CAS# % by Weight
TETRACYCLINE HYDROCHLORIDE 64-75-5 100
Toxicological Data on Ingredients:
LD50 (Oral, Rat): 6443 mg/kg
LD50 (Oral, Mouse): 2759 mg/kg
3: Hazards Identification
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Potential Acute Health Effects: Irritant.
Irritating to eyes, respiratory system and skin. Photosensitizer. Calif. Prop. 65 reproductive hazard.
Target organ(s): Liver. Teeth. Bones.
Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: Suspected carcinogen.
MUTAGENIC EFFECTS: Mutation in mammalian somatic cells.
TERATOGENIC EFFECTS: Possible risk of congenital malformation in the fetus.
DEVELOPMENTAL TOXICITY: Effects on fertility.
4: First Aid Measures
Eye Contact: In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.
Skin Contact: In case of contact, immediately wash skin with soap and copious amounts of water.
Serious Skin Contact: Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek
medical attention.
Inhalation: If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
Serious Inhalation: Not available.
Ingestion: If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Serious Ingestion: Not available.
5: Fire and Explosion Data
Flammability of the Product: May be combustible at high temperature.
Auto-Ignition Temperature: Not available.
Flash Points: Not available.
Flammable Limits: Not available.
Product of Combustion: Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen chloride gas.
Fire Hazards in Presence of Various Substances: Not available.
Explosion Hazards in Presence of Various Substances:
Not available.
Fire Fighting Media and Instructions:
SMALL FIRE: Dry chemical powder.
LARGE FIRE: Water spray. Carbon dioxide, dry chemical powder, or appropriate foam.
Special Remarks on Fire Hazards: Not available.
Special Remarks on Explosion Hazards: Not available.
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6: Accidental Release Measures
Small Spill: Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site
after material pickup is complete.
Large Spill: Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading
water on the contaminated surface and allow to evacuate through the sanitary system.
7: Handling and Storage
Precautions: Do not breathe dust. Avoid contact with eyes, skin, and clothing. Avoid prolonged or repeated exposure.
Storage: Keep tightly closed.
8: Exposure Controls/Personal Protection
Engineering Controls: Safety shower and eye bath. Mechanical exhaust required.
Personal Protection: Respiratory: Use respirators and components tested and approved under appropriate government
standards such as NIOSH (US) or CEN (EU).
Hand: Compatible chemical-resistant gloves.
Eye: Chemical safety goggles.
Personal Protection in Case of a Large Spill: Splash goggles. Full suit. Boots. Dust respirator. Gloves.
Exposure Limits: Not available.
9: Physical and Chemical Properties
Physical State and Appearance: Solid.
Odor: Not available.
Taste: Not available.
Molecular Weight: 480.90 g/mole
Color: Yellow.
pH(1% soln/water): 1.8 - 2.8
Boiling Point: Not available.
Melting Point: 220.0 - 223.0 掳C
Critical Temperature: Not available.
Specific Gravity: Not available.
Vapour Pressure: Not available.
Vapor Density: Not available.
Volatility: Not available.
Odor Threshold: Not available.
Water/Oil Dist. Coeff: Not available.
Ionicity (in Water): Not available.
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Dispersion Properties: Not available.
Solubility: Soluble in ethanol.
10: Stability and Reactivity Data
Stability: Stable.
Instability Temperature: Not available.
Conditions of Instability: May discolor on exposure to light.
Incompatibility with various substances: Strong oxidizing agents.
Corrosivity: Not available.
Special Remarks on Reactivity: Not available.
Special Remarks on Corrosivity: Not available.
Polymerization: Will not occur.
11:Toxicological Information
Routes of Entry: Skin contact. Eye contact. Ingestion. Inhalation.
Toxicity to Animals:
LD50 (Oral, Rat): 6443 mg/kg
LD50 (Intraperitoneal, Rat): 318 mg/kg
LD50 (Subcutaneous, Rat): 700 mg/kg
LD50 (Intravenous, Rat): 128 mg/kg
LD50 (Oral, Mouse): 2759 mg/kg
LD50 (Intraperitoneal, Mouse): 368 mg/kg
LD50 (Intravenous, Mouse): 157 mg/kg
Chronic Effects on Humans: Carcinogen: This product is or contains a component that is probably not carcinogenic
based on its IARC, ACGIH, NTP, or EPA classification.
Teratogen : Possible risk of congenital malformation in the fetus.
Mutagen : DNA damage; Mutation in mammalian somatic cells.
Reproductive Hazard: Post-implantation mortality (e.g., dead and/or resorbed implants per total number of implants);
Abortion; Effects on Embryo or Fetus (Extra embryonic structures (e.g., placenta, umbilical cord)).
Other Toxic Effects on Humans: Skin Contact: Causes skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: Causes eye irritation.
Inhalation: Material is irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.
Ingestion: May be harmful if swallowed.
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans: Possible risk of harm to unborn child.
Special Remarks on other Toxic Effects on Humans: Can cause phototoxic reactions, gastrointestinal disturbances,
turn teeth yellow and reduce mineralization.
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12: Ecological Information
Ecotoxicity: Not available.
BOD5 and COD: Not available.
Product of Biodegradation: Not available.
Toxicity of the Products of Biodegradation: Not available.
Special Remarks on the Products of Biodegradation: Not available.
13: Disposal Considerations
Waste Disposal: Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the
material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Observe
all federal, state, and local environmental regulations.
14: Transport Information
DOT Classification: Not a DOT controlled material.
Identification: Not available.
Special Provisions for Transport: Not available.
15: Other Regulatory Information
Federal and State Regulations: TSCA 8(b) inventory : Tetracycline Hydrochloride
Other Regulations: EU ADDITIONAL CLASSIFICATION
Symbol of Danger: Xi
Indication of Danger: Irritant.
R: 36/37/38
Risk Statements: Irritating to eyes, respiratory system and skin.
S: 26-36
Safety Statements: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear
suitable protective clothing.
Other Classifications:
WHMIS(Canada): This product has a WHMIS classification of D2A.
DSCL(EEC): Not available.
HMIS(U.S.A):
Health Hazard: 3
Fire Hazard: 0
Reactivity: 1
Personal Protection:
National Fire Protection Association (U.S.A):
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Health: 3
Flammability: 0
Reactivity: 1
Specific hazard:
Protective Equipment: Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.
Safety goggles.
16: Other Information
References: Not available.
Other Special Considerations: Not available.
Created: 07/09/2006 10:16:49 AM
Last Updated: 07/09/2006 11:51:58 AM
Disclaimer
This product is offered by bioWORLD for research, laboratory or further manufacturing use. Not for human use or
consumption.
The information above is believed to be accurate and represents the best information currently available to us. However,we
make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we
assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the
information for their particular purposes.In no event shall Bio-World.com be liable for any claims, losses, or damages of any
third party or for lost profits or any special, indirect,incidental,consequential or exemplary damages, howsoever arising,
even if Bio-World.com has been advised of the possibility of such damages.
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