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Material Safety Data Sheet
CEFOTAXIME SODIUM
1: Chemical Product and Company Identification
Product Name: CEFOTAXIME SODIUM
Contact information:
Catalog Code: 762076, 762077, 762078, 762079
bioWORLD
CAS#: 64485-93-4 4150 Tuller Rd
Suite 228, Dublin, OH 43017, USA
RTECS: XI0250000
For information, call: 614-792-8680
TSCA: Not available. Fax Number: 614-792-8685
Order Online:www.bio-world.com
CI#: Not available.
E-mail : save@bio-world.com
Synonym: Cefotaxime sodium, Claforan, CTX, HR 756, Sodium
7-(2-(2-amino-4-thiazolyl)-2-methoxyiminoacetamido) In Case of a chemical emergency, call CHEMTREC
cephalosporanate, RU 24756. (24 hours a day) at 1-800-424-9300
Chemical Name: CEFOTAXIM SODIUM SALT For non-emergency assistance,call: 1-800-860-9729
Chemical Formula: C16H16N5NaO7S2
2: Composition and Information on Ingredients
Composition:
Name CAS# % by Weight
CEFOTAXIM SODIUM SALT 64485-93-4 100
Toxicological Data on Ingredients:
LD50 (Oral, Rat): 20,000 mg/kg
LD50 (Oral, Mouse): 20,000 mg/kg
3: Hazards Identification
Potential Acute Health Effects: Harmful. May cause sensitization by inhalation and skin contact. Irritating to eyes,
respiratory system and skin.
Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: Not available.
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MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Effects on Embryo or Fetus: Fetal death.
DEVELOPMENTAL TOXICITY: Not available.
4: First Aid Measures
Eye Contact: Not available.
Skin Contact: Not available.
Serious Skin Contact: Not available.
Inhalation: If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
Serious Inhalation: Not available.
Ingestion: If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Serious Ingestion: Not available.
5: Fire and Explosion Data
Flammability of the Product: Not available.
Auto-Ignition Temperature: Not available.
Flash Points: Not available.
Flammable Limits: Not available.
Product of Combustion: Carbon monoxide, Carbon dioxide, Sulfur oxides, Nitrogen oxides, Sodium/sodium oxides.
Fire Hazards in Presence of Various Substances: Not available.
Explosion Hazards in Presence of Various Substances:
Risks of explosion of the product in presence of mechanical impact : Not available.
Risks of explosion of the product in presence of static discharge : Not available.
Fire Fighting Media and Instructions:
SMALL FIRE: Dry chemical powder.
LARGE FIRE: Water spray. Carbon dioxide. Dry chemical powder, or appropriate foam.
Special Remarks on Fire Hazards: Not available.
Special Remarks on Explosion Hazards: Dust Potential: This material, like most materials in powder form, is capable of
creating a dust explosion.
6: Accidental Release Measures
Small Spill: Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site
after material pickup is complete.
Large Spill: Not available.
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7: Handling and Storage
Precautions: Do not breathe dust. Do not get in eyes, on skin, on clothing. Avoid prolonged or repeated exposure.
Storage: Keep tightly closed. Store in a cool dry place. Store at 2-8掳C
8: Exposure Controls/Personal Protection
Engineering Controls: Use only in a chemical fume hood. Safety shower and eye bath.
Personal Protection: Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other
protective clothing.
Personal Protection in Case of a Large Spill: Safety goggles. Gloves. Dust respirator. Lab coat.
Exposure Limits: Not available.
9: Physical and Chemical Properties
Physical State and Appearance: Powder
Odor: Not available.
Taste: Not available.
Molecular Weight: 477.5 g/mole
Color: Very faintly beige
pH(1% soln/water): Not available.
Boiling Point: Not available.
Melting Point: Not available.
Critical Temperature: Not available.
Specific Gravity: Not available.
Vapour Pressure: Not available.
Vapor Density: Not available.
Volatility: Not available.
Odor Threshold: Not available.
Water/Oil Dist. Coeff: Not available.
Ionicity (in Water): Not available.
Dispersion Properties: Not available.
Solubility: Soluble in water.
10: Stability and Reactivity Data
Stability: Stable.
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Instability Temperature: Not available.
Conditions of Instability: Not available.
Incompatibility with various substances: Strong oxidizing agents.
Corrosivity: Not available.
Special Remarks on Reactivity: Not available.
Special Remarks on Corrosivity: Not available.
Polymerization: Will not occur
11:Toxicological Information
Routes of Entry: Ingestion. Inhalation.
Toxicity to Animals:
LD50 (Oral Rat):> 20000 mg/kg; LD50 (Intraperitoneal, Rat):10 g/kg ;LD50 (Subcutaneous, Rat):18400 mg/kg; LD50
(Intravenous, Rat):7 mg/kg; LD50 (Intramuscular, Rat) :>2 mg/kg; LD50 (Oral Mouse):> 20000 mg/kg ;LD50(Intraperitoneal,
Mouse):10 mg/kg; LD50 (Subcutaneous, mouse):12950 mg/kg;LD50(Intravenous, Mouse):6845 mg/kg; LD50(Intravenous,
Dog):>1500 mg/kg; LD50(Intramuscular Dog):>716 mg/kg; LD50 (Intravenous Rabbit):1880 mg/kg
Chronic Effects on Humans: Effects on Embryo or Fetus: Fetal death.
Other Toxic Effects on Humans: Inhalation: Material is irritating to mucous membranes and upper respiratory tract.
Multiple Routes: May be harmful by inhalation, ingestion, or skin absorption. Causes eye and skin irritation.
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans: Not available.
Special Remarks on other Toxic Effects on Humans: Not available.
12: Ecological Information
Ecotoxicity: Not available.
BOD5 and COD: Not available.
Product of Biodegradation: Not available.
Toxicity of the Products of Biodegradation: Not available.
Special Remarks on the Products of Biodegradation: Not available.
13: Disposal Considerations
Waste Disposal: Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with
an afterburner and scrubber. Observe all federal, state, and local environmental regulations.
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14: Transport Information
DOT Classification: Not a DOT controlled material.
Identification: Not available.
Special Provisions for Transport: This substance is considered to be non-hazardous for transport.
15: Other Regulatory Information
Federal and State Regulations: Indication of Danger: Harmful.
Risk Statements: May cause sensitization by inhalation and skin contact. Irritating to eyes, respiratory system and skin.
Safety Statements: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear
suitable protective clothing.
UNITED STATES REGULATORY INFORMATION
SARA LISTED: No
Other Regulations: EU ADDITIONAL CLASSIFICATION
Symbol of Danger: Xn
Indication of Danger: Harmful.
R: 42/43
Risk Statements: May cause sensitization by inhalation and skin contact.
S: 22 36/37
Safety Statements: Do not breathe dust. Wear suitable protective clothing and gloves.
Other Classifications:
WHMIS(Canada): This product has been classified in accordance with the hazard criteria of the CPR, and the MSDS
contains all the information required by the CPR.
DSCL(EEC): Not available.
HMIS(U.S.A):
Health Hazard: 0
Fire Hazard: 1
Reactivity: 0
Personal Protection: A
National Fire Protection Association (U.S.A):
Health: 0
Flammability: 1
Reactivity: 0
Specific hazard:
Protective Equipment: Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles,
other protective clothing.
16: Other Information
References: Not available.
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Other Special Considerations: Not available.
Created: 23/06/2006 2:25:53 PM
Last Updated: 18/07/2006 11:42:05 AM
The information above is believed to be accurate and represents the best information currently available to us. However,we
make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we
assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the
information for their particular purposes.In no event shall Bio-World.com be liable for any claims, losses, or damages of any
third party or for lost profits or any special, indirect,incidental,consequential or exemplary damages, howsoever arising,
even if Bio-World.com has been advised of the possibility of such damages.
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