SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 16/JUN/2005
Date Updated: 17/MAR/2004
Version 1.3
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name 3,4-DIMETHYLPHENOL, 99%
Product Number D175404
Company Sigma-Aldrich Pty. Ltd.
12 Anella Avenue
Castle Hill NSW 2154
Australia
Technical Phone # +61 2 9841 0555 (1800 800 097)
Fax +61 2 9841 0500 (1800 800 096)
Emergency Phone # +44 8701906777 (1800 448 465)
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
3,4-DIMETHYLPHENOL 95-65-8 202-439-5 604-006-00-X
Formula C8H10O
Molecular Weight 122.17 AMU
Synonyms 3,4-Dimethylphenol * 4,5-Dimethylphenol *
Phenol, 3,4-dimethyl- (9CI) * 1,3,4-Xylenol
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Toxic in contact with skin and if swallowed. Causes burns. Toxic
to aquatic organisms, may cause long-term adverse effects in the
aquatic environment.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER EYE CONTACT
Assure adequate flushing of the eyes by separating the eyelids
with fingers.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
CONDITIONS OF FLAMMABILITY
Under fire conditions, material may decompose to form flammable
and/or explosive mixtures in air.
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Cover with dry-lime, sand, or soda ash. Place in covered
containers using non-sparking tools and transport outdoors.
Ventilate area and wash spill site after material pickup is
complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe dust. Do not get in
eyes, on skin, on clothing. Avoid prolonged or repeated exposure.
STORAGE
Conditions of Storage: Keep tightly closed. Store in a cool dry
place.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Use only in a chemical fume hood. Safety shower and eye bath.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling. Discard contaminated clothing and
shoes.
PERSONAL PROTECTIVE EQUIPMENT
Special Protective Measures: Wear appropriate government approved
respirator, chemical-resistant gloves, safety goggles, other
protective clothing. Faceshield (8-inch minimum).
9 - Physical and Chemical Properties
Appearance Color: Faintly brown
Form: Crystals
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 227 掳C 760 mmHg
MP/MP Range 63 掳C
Flash Point 110 掳C Method: closed cup
Flammability N/A
Autoignition Temp N/A
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Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density N/A
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Materials to Avoid: Bases, Acid chlorides, Acid anhydrides,
Oxidizing agents, Brass Copper, Copper alloys.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
11 - Toxicological Information
RTECS NUMBER: ZE6300000
ACUTE TOXICITY
LD50
Oral
Rat
727 mg/kg
LD50
Intraperitoneal
Rat
200 MG/KG
Remarks: Behavioral:Somnolence (general depressed activity).
Kidney, Ureter, Bladder:Other changes in urine composition. Skin
and Appendages: Other: Hair.
LD50
Oral
Mouse
400 mg/kg
Remarks: Behavioral:Ataxia. Behavioral:Muscle contraction or
spasticity. Lungs, Thorax, or Respiration:Dyspnea.
LD50
Intraperitoneal
Mouse
50 MG/KG
Remarks: Behavioral:Somnolence (general depressed activity).
Behavioral:Ataxia. Skin and Appendages: Other: Hair.
LD50
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Oral
Rabbit
800 mg/kg
Remarks: Behavioral:Ataxia. Behavioral:Muscle contraction or
spasticity. Lungs, Thorax, or Respiration:Dyspnea.
SIGNS AND SYMPTOMS OF EXPOSURE
Material is extremely destructive to tissue of the mucous
membranes and upper respiratory tract, eyes, and skin.
Inhalation may result in spasm, inflammation and edema of the
larynxand bronchi, chemical pneumonitis, and pulmonary edema.
Symptoms of exposure may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea, and
vomiting.
ROUTE OF EXPOSURE
Multiple Routes: Harmful if swallowed, inhaled, or absorbed
through skin. Causes burns.
CHRONIC EXPOSURE - CARCINOGEN
Mouse
Route of Application: Skin
Exposure Time: 20W
Result: Tumorigenic:Equivocal tumorigenic agent by RTECS
criteria. Skin and Appendages: Other: Tumors.
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Dissolve or mix the material with a combustible solvent and burn
in a chemical incinerator equipped with an afterburner and
scrubber. Observe all federal, state, and local environmental
regulations.
14 - Transport Information
RID/ADR
UN#: 2261
Class: 6.1
PG: II
Kemmler Number: 60
Proper Shipping Name: XYLENOLS, SOLID
IMDG
UN#: 2261
Class: 6.1
PG: II
Proper Shipping Name: XYLENOLS, SOLID
Marine Pollutant: No
Severe Marine Pollutant: No
IATA
UN#: 2261
Class: 6.1
PG: II
Proper Shipping Name: Xylenols
Inhalation Packing Group I: No
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15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 604-006-00-X
INDICATION OF DANGER: T N
Toxic. Dangerous for the environment.
R-PHRASES: 24/25 34 51/53
Toxic in contact with skin and if swallowed. Causes burns.
Toxic to aquatic organisms, may cause long-term adverse effects
in the aquatic environment.
S-PHRASES: 26 36/37/39 45 61
In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice. Wear suitable protective
clothing, gloves, and eye/face protection. In case of accident
or if you feel unwell, seek medical advice immediately (show
the label where possible). Avoid release to the environment.
Refer to special instructions/safety data sheets.
SWITZERLAND
SWISS POISON CLASS: 4
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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