Product # (s) 7380________________
MATERIAL SAFETY DATA SHEET
Section I 鈥? Product Information
Product Name or Identity: Phosphate Buffer, pH 7.2
Acumedia Manufacturers, Inc. 517/372-9200
Manufacturer鈥檚 Name: Emergency Phone No.:
740 East Shiawassee 517/372-2006
Fax No.:
Lansing, Michigan 48912 foodsafety@neogen.com
e-mail:
Date Prepared or Revised: 10/10/04
Section II 鈥? Hazardous Ingredients / Identity Information
Hazardous Components: OSHA PEL ACGIH TLV Toxicity Data LD50
(Specific Chemical Identity: Common Names) (Permissible (Threshold Limit
Exposure Limits) Value)
Potassium Phosphate N/A N/A SKN-RBT, >4640 mg/kg
Sodium Carbonate N/A N/A ORL-RAT, 4090 mg/kg
Section III 鈥? Physical Characteristics
Boiling Point: N/A Specific Gravity (H2O = 1): 2.53 (Sodium Carbonate)
Vapor Pressure (mm Hg.): N/A Melting Point: >465掳C (Potassium Phosphate), 851掳C (Sodium Carbonate)
Vapor Density (AIR = 1): N/A Evaporation Rate (Butyl Acetate = 1): N/A
Solubility in Water: 150 g/ 100 g cold water (Potassium Phosphate), 45.5 g/100 mL water @ 100 (Sodium Carbonate)
Appearance and Odor: White crystals or powder, odorless (Potassium Phosphate), White powder, odorless (Sodium Carbonate).
Section IV 鈥? Fire and Explosion Hazard Data
Flash Point (Method Used): Not applicable Flammable Limits: LEL (Lower Explosive Limit) - N/A
UEL (Upper Explosive Limit) - N/A
Extinguishing Media: Suitable extinguishing agents. CO2, extinguishing powder, or water spray.
Special Fire Fighting Procedures: Fight larger fires with water or alcohol resistant foam. Firefighters should wear
protective equipment and self-contained breathing apparatus. Remove contaminated clothing immediately.
Unusual Fire and Explosion Hazards: During heating or in case of fire, poisonous gases are produced. As with most
organic solids, fire is possible at elevated temperatures or by contact with an ignition source.
Section V 鈥? Reactivity Data
Unstable Conditions to Avoid: Protect from light and moisture. Slightly hygroscopic.
Stability:
Stable X
Incompatibility (Materials to Avoid): Strong oxidizers
Hazardous Decomposition or Byproducts: Burning may produce Phosphorus oxides, Carbon monoxide, Carbon
dioxide, Nitrogen oxides. Combustion will produce Carbon dioxide, Carbon monoxide, hydrogen bromide gas.
May Occur Conditions to Avoid: Moisture, light and incompatible materials.
Hazardous
Polymerization:
Will Not Occur X
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Product # (s) 7380_______________
Section VI 鈥? Health Hazard Data
Inhalation? N/A Skin? N/A Ingestion? N/A
Route(s) of Entry:
Irritant. Irritating to eyes, respiratory system, and skin. May cause harm if swallowed.
Health Hazards:
(Acute and Chronic)
Carcinogenicity: NTP? No IARC Monographs? No OSHA Regulated? No
(National Toxicology Program) (International Agency for Research in Cancer)
Signs and Symptoms of Exposure: Inhalation of dust may cause irritation to the respiratory tract. Symptoms may
include coughing and difficult breathing. May cause eye irritation.
Medical Conditions Generally Aggravated by Exposure: Phosphates are slowly and incompletely absorbed when
ingested. Symptoms may include vomiting, lethargy, diarrhea, blood chemistry effects, cardiac effects and central nervous
system. The toxicity of phosphates is their ability to sequester calcium. May sequester calcium and cause calcium
phosphate deposits in the kidneys. Persons with impaired kidney function may be more susceptible to the effects of the
substance.
Ingestion: If swallowed, seek medical attention.
Emergency /
First Aid
Inhalation: Supply fresh air or oxygen. Seek medical attention immediately. In case of
Procedures:
unconsciousness, place patient on side position for transportation. If required, provide artificial
respiration.
Eye Contact: Rinse opened eye for at least 15 minutes under running water. Seek medical attention.
Skin Contact: Wash with plenty of soap and water for at least 15 minutes. If irritation develops seek
medical attention.
Section VII 鈥? Precautions for Safe Handling and Use
Accidental Release Measures: Ventilate spill area. Wipe up with damp sponge or mop. Wear suitable protective
clothing. Avoid inhalation, contact with eyes, skin, and clothing. Remove contaminated clothing immediately. In case of
fire, use sand, carbon dioxide, or powdered extinguishing agent.
Waste Disposal Method: Dispose in accordance with all applicable federal, state, and local environmental regulations.
Handling and Storing: Keep container tightly closed. Suitable for any general chemical storage area. Protect from
moisture. Keep receptacle tightly sealed.
Other Precautions: Prevent formation of dust. Do not breathe dust. Ensure good ventilation / exhaustion at the
workplace. Prevent prolonged or repeated exposure.
Section VIII 鈥? Control Measures
Respiratory Protection (Specify Type): None required where adequate ventilation conditions exist. If airborne
concentration is high, use an appropriate respirator or dust mask.
Local Exhaust: 50 鈥? 100 CFM Special: N/A
Ventilation:
Mechanical (General): N/A Other: N/A
Protective Gloves: Proper disposable gloves Eye Protection: Chemical resistant safety goggles
Other Protective Clothing or Equipment: Long-sleeved lab coat, safety shower , and eye wash recommended.
Work / Hygienic Practices: Follow the usual precautionary measures for handling chemicals / powder. Keep away from
food and beverages. Immediately remove all soiled and contaminated clothing. Avoid contact with eyes, skin, and
clothing.
This document is believed to be correct, but does not purport to be all inclusive and shall be used only as a guide.
Acumedia Manufacturers, Inc. shall not be held liable for any damage resulting from handling or from contact with the
above product. These suggestions should not be confused with state, municipal or insurance requirements, and constitute
NO WARRANTY.
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