**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
|----------------|--------------------------------------|----------|-----------|
| 108-88-3 |Toluene | 20-50 | 203-625-9 |
|----------------|--------------------------------------|----------|-----------|
| 109-99-9 |Tetrahydrofuran | 35-50 | 203-726-8 |
|----------------|--------------------------------------|----------|-----------|
| 873-77-8 |4-Chlorophenylmagnesium bromide | 20 | 212-853-8 |
+----------------+--------------------------------------+----------+-----------+
Text for R-phrases: see Section 16
Hazard Symbols: F C
Risk Phrases: 11 14/15 19 34 20 63 67
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Highly flammable. Reacts violently with water liberating extremely
flammable gases. May form explosive peroxides. Causes burns. Harmful
by inhalation. Possible risk of harm to the unborn child. Vapours
may cause drowsiness and dizziness.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Causes skin burns.
Ingestion:
Causes gastrointestinal tract burns.
Inhalation:
Harmful if inhaled. Causes chemical burns to the respiratory tract.
Chronic:
Not available.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid
immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of
water for at least 15 minutes while removing contaminated clothing
and shoes.
Ingestion:
Do not induce vomiting. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen.
Notes to Physician:
Treat symptomatically and supportively.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Will burn if involved in a fire. Water Reactive.
Material will react with water and may release a flammable and/or
toxic gas. Extremely flammable liquid and vapor. May form explosive
peroxides.
Extinguishing Media:
Use foam, dry chemical, or carbon dioxide. Do NOT use carbon
dioxide. DO NOT USE WATER OR FOAM. Smother with dry sand, dry clay,
dry ground limestone (CaCO3), or use approved Class D extinguishers.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Remove all sources of ignition.
Use a spark-proof tool. Do not expose spill to water.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Use spark-proof tools and explosion proof equipment. Do not breathe
dust, vapor, mist, or gas. Do not get in eyes, on skin, or on
clothing. Do not allow contact with water. Use only in a chemical
fume hood.
Storage:
Keep away from sources of ignition. Store in a cool, dry place. Do
not store in direct sunlight. Store in a tightly closed container.
Flammables-area. Corrosives area. Water free area. Store under
nitrogen.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local explosion-proof ventilation to keep airborne levels to
acceptable levels.
Exposure Limits
CAS# 108-88-3:
United Kingdom, WEL - TWA: 50 ppm TWA; 191 mg/m3 TWA
United Kingdom, WEL - STEL: 150 ppm STEL; 574 mg/m3 STEL
United States OSHA: 200 ppm TWA; 300 ppm Ceiling
Belgium - TWA: 50 ppm VLE; 191 mg/m3 VLE
France - VME: 100 ppm VME; 375 mg/m3 VME
France - VLE: 150 ppm VLE; 550 mg/m3 VLE
Germany: 50 ppm TWA; 190 mg/m3 TWA
Germany: Skin absorber
Japan: 50 ppm OEL; 188 mg/m3 OEL
Malaysia: 50 ppm TWA; 188 mg/m3 TWA
Netherlands: 40 ppm MAC; 150 mg/m3 MAC
Russia: 50 mg/m3 TWA
Spain: 50 ppm VLA-ED; 191 mg/m3 VLA-ED
CAS# 109-99-9:
United Kingdom, WEL - TWA: 50 ppm TWA; 150 mg/m3 TWA
United Kingdom, WEL - STEL: 100 ppm STEL; 300 mg/m3 STEL
United States OSHA: 200 ppm TWA; 590 mg/m3 TWA
Belgium - TWA: 200 ppm VLE; 599 mg/m3 VLE
Belgium - STEL: 100 ppm VLE; 300 mg/m3 VLE
France - VME: 200 ppm VME; 590 mg/m3 VME
Germany: 50 ppm TWA; 150 mg/m3 TWA
Germany: Skin absorber
Japan: 200 ppm OEL; 590 mg/m3 OEL
Malaysia: 200 ppm TWA; 590 mg/m3 TWA
Netherlands: 100 ppm MAC; 300 mg/m3 MAC
Russia: 100 mg/m3 TWA
Spain: 50 ppm VLA-ED; 150 mg/m3 VLA-ED
Spain: 100 ppm VLA-EC; 300 mg/m3 VLA-EC
CAS# 873-77-8:
Personal Protective Equipment
Eyes:
Not available.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Liquid
Color: dark brown
Odor: solvent odor
pH: >7
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: vigorous reaction
Specific Gravity/Density: 1.000
Molecular Formula: C6H4BrClMg
Molecular Weight: 215.76
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Reacts violently with water. Moisture sensitive. Light sensitive.
Conditions to Avoid:
Incompatible materials, ignition sources, exposure to moist air or
water, direct sunlight..
Incompatibilities with Other Materials:
Water, oxidizing agents, acids, alcohols.
Hazardous Decomposition Products:
Chlorine, carbon monoxide, carbon dioxide, ammonia and hydrochloric
acid fumes, hydrogen bromide, benzene, oxides of magnesium, bromine.
Hazardous Polymerization: Has not been reported
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 108-88-3: XS5250000
CAS# 109-99-9: LU5950000
CAS# 873-77-8 unlisted.
LD50/LC50:
CAS# 108-88-3: Draize test, rabbit, eye: 870 ug Mild; Draize test,
rabbit, eye: 2 mg/24H Severe; Draize test, rabbit, skin: 435 mg Mild;
Draize test, rabbit, skin: 500 mg Moderate; Draize test, rabbit,
skin: 20 mg/24H Moderate; Inhalation, mouse: LC50 = 400 ppm/24H;
Inhalation, mouse: LC50 = 30000 mg/m3/2H; Inhalation, mouse: LC50 =
19900 mg/m3/7H; Inhalation, mouse: LC50 = 10000 mg/m3; Inhalation,
rat: LC50 = 49 gm/m3/4H; Oral, rat: LD50 = 636 mg/kg; Skin, rabbit:
LD50 = 14100 uL/kg.
CAS# 109-99-9: Inhalation, rat: LC50 = 21000 ppm/3H; Oral, rat: LD50
= 1650 mg/kg.
CAS# 873-77-8.
Carcinogenicity:
Toluene -
Not listed by ACGIH, IARC, or NTP.
Tetrahydrofuran -
ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to
4-Chlorophenylmagnesium bromide -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: ORGANOMETALLIC COMPOUND SOLUTION, WATER-REACTIVE,
FLAMMABLE, N.O.S.*
Hazard Class: 4.3 (3)
UN Number: 3207
Packing Group: I
IMO
Shipping Name: ORGANOMETALLIC COMPOUND SOLUTION, WATER-REACTIVE,
FLAMMABLE, N.O.S.
Hazard Class: 4.3 (3)
UN Number: 3207
Packing Group: I
RID/ADR
Shipping Name: ORGANOMETALLIC COMPOUND SOLUTION, WATER-REACTIVE,
FLAMMABLE, N.O.S.
Hazard Class: 4.3 (3)
UN Number: 3207
Packing group: I
USA RQ: CAS# 108-88-3: 1000 lb final RQ; 454 kg final RQ
USA RQ: CAS# 109-99-9: 1000 lb final RQ; 454 kg final RQ
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: F C
Risk Phrases:
R 11 Highly flammable.
R 14/15 Reacts violently with water liberating
extremely flammable gases.
R 19 May form explosive peroxides.
R 20 Harmful by inhalation.
R 34 Causes burns.
R 63 Possible risk of harm to the unborn child.
R 67 Vapours may cause drowsiness and dizziness.
Safety Phrases:
S 6A Keep under nitrogen.
S 7/8 Keep container tightly closed and dry.
S 16 Keep away from sources of ignition - No
smoking.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 33 Take precautionary measures against static
discharges.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 43B In case of fire, use fire-fighting equipment
on basis of sodium chloride, sodium bicarbonate (never
use water).
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 108-88-3: 2
CAS# 109-99-9: 1
CAS# 873-77-8: No information available.
Canada
CAS# 108-88-3 is listed on Canada's DSL List.
CAS# 109-99-9 is listed on Canada's DSL List.
CAS# 108-88-3 is listed on Canada's Ingredient Disclosure List.
CAS# 109-99-9 is listed on Canada's Ingredient Disclosure List.
CAS# 873-77-8 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 108-88-3 is listed on the TSCA inventory.
CAS# 109-99-9 is listed on the TSCA inventory.
CAS# 873-77-8 is not listed on the TSCA inventory.
It is for research and development use only.
**** SECTION 16 - ADDITIONAL INFORMATION ****
Text for R-phrases from Section 2
R 11 Highly flammable.
R 19 May form explosive peroxides.
R 36/37 Irritating to eyes and respiratory system.
R 20 Harmful by inhalation.
MSDS Creation Date: 9/20/2004 Revision #0 Date: Original.
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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