**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
|----------------|--------------------------------------|----------|-----------|
| 123-91-1 |1,4-Dioxane | 14-17% | 204-661-8 |
|----------------|--------------------------------------|----------|-----------|
| 367-93-1 |Isopropyl-beta-d-thiogalactopyranoside| 83-86 | 206-703-0 |
| | | | |
+----------------+--------------------------------------+----------+-----------+
Text for R-phrases: see Section 16
Hazard Symbols: XN
Risk Phrases: 19 40
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
May form explosive peroxides. Limited evidence of a carcinogenic
effect.The toxicological properties of this material have not been
fully investigated.
Potential Health Effects
Eye:
May cause eye irritation. Contact may cause transient eye
irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological
properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties
of this substance have not been fully investigated.
Chronic:
May cause cancer according to animal studies.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid
immediately.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Wash clothing
before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4
cupfuls of milk or water. Never give anything by mouth to an
unconscious person. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If not
breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical aid if cough or other symptoms appear.
Notes to Physician:
Antidote:
None reported.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Combustion generates toxic fumes. During a fire,
irritating and highly toxic gases may be generated by thermal
decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective
Equipment section. Sweep up or absorb material, then place into a
suitable clean, dry, closed container for disposal. Avoid generating
dusty conditions. Provide ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid contact with eyes,
skin, and clothing. Keep container tightly closed. Avoid ingestion
and inhalation.
Storage:
Deep freeze (below -20C). Keep containers tightly closed.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 123-91-1:
United Kingdom, WEL - TWA: 25 ppm TWA; 91 mg/m3 TWA
United Kingdom, WEL - STEL: 100 ppm STEL; 366 mg/m3 STEL
United States OSHA: 100 ppm TWA; 360 mg/m3 TWA
Belgium - TWA: 25 ppm VLE; 91 mg/m3 VLE
France - VME: 10 ppm VME; 35 mg/m3 VME
France - VLE: 40 ppm VLE; 140 mg/m3 VLE
Germany: 20 ppm TWA; 73 mg/m3 TWA
Germany: Skin absorber
Japan: 10 ppm OEL; 36 mg/m3 OEL
Malaysia: 20 ppm TWA; 72.1 mg/m3 TWA
Netherlands: 22 ppm STEL; 80 mg/m3 STEL
Netherlands: 11 ppm MAC; 40 mg/m3 MAC
Russia: 10 mg/m3 TWA
Spain: 20 ppm VLA-ED; 74 mg/m3 VLA-ED
CAS# 367-93-1:
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize
contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Solid
Color: white
Odor: none reported
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 122 - 124 deg C
Autoignition Temperature: Not applicable.
Flash Point: > 110 deg C (> 230.00 deg F)
Explosion Limits, lower: N/A
Explosion Limits, upper: N/A
Decomposition Temperature:
Solubility in water: soluble in water
Specific Gravity/Density:
Molecular Formula: C9H18O5S
Molecular Weight: 238.30
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures. May form explosive
peroxides. Under normal storage conditions, peroxidizable compounds
can form and accumulate peroxides which may explode when subjected to
heat or shock. This material is most hazardous when peroxide levels
are concentrated by distillation or evaporation.
Conditions to Avoid:
High temperatures, incompatible materials, dust generation.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, oxides of sulfur, carbon dioxide.
Hazardous Polymerization: Has not been reported.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 123-91-1: JG8225000
CAS# 367-93-1 unlisted.
LD50/LC50:
CAS# 123-91-1: Draize test, rabbit, eye: 100 mg Severe; Draize test,
rabbit, eye: 100 mg/24H Moderate; Inhalation, mouse: LC50 = 37
gm/m3/2H; Inhalation, rat: LC50 = 46 gm/m3/2H; Oral, mouse: LD50 =
5300 mg/kg; Oral, rabbit: LD50 = 2 gm/kg; Oral, rat: LD50 = 4200
mg/kg; Skin, rabbit: LD50 = 7600 uL/kg.
CAS# 367-93-1.
Carcinogenicity:
1,4-Dioxane -
ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to
California: carcinogen, initial date 1/1/88
NTP: Suspect carcinogen
IARC: Group 2B carcinogen
Isopropyl-beta-d-thiogalactopyranoside -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Other
No information available.
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Products which are considered hazardous for supply are classified as Special
Waste and the disposal of such chemicals is covered by regulations which may
vary according to location. Contact a specialist disposal company or the local
waste regulator for advice. Empty containers must be decontaminated before
returning for recycling.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
USA RQ: CAS# 123-91-1: 100 lb final RQ; 45.4 kg final RQ
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 19 May form explosive peroxides.
R 40 Limited evidence of a carcinogenic effect.
Safety Phrases:
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 123-91-1: 2
CAS# 367-93-1: No information available.
Canada
CAS# 123-91-1 is listed on Canada's DSL List.
CAS# 367-93-1 is listed on Canada's DSL List.
CAS# 123-91-1 is listed on Canada's Ingredient Disclosure List.
CAS# 367-93-1 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 123-91-1 is listed on the TSCA inventory.
CAS# 367-93-1 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
Text for R-phrases from Section 2
MSDS Creation Date: 11/12/1998 Revision #6 Date: 3/03/2005
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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