**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 1635-61-6 |5-Chloro-2-Nitroaniline | 97% | 216-661-5 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: T+ N
Risk Phrases: 26/27/28 33 51/53
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Very toxic by inhalation, in contact with skin and if swallowed.
Danger of cumulative effects. Toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. Absorption into the body may cause
cyanosis (bluish discoloration of skin due to deficient oxygenation
of the blood).
Ingestion:
May cause irritation of the digestive tract. May cause liver and
kidney damage. May cause cardiac disturbances. May cause
methemoglobinemia, cyanosis (bluish discoloration of skin due to
deficient oxygenation of the blood), convulsions, and death. May
cause central nervous system depression.
Inhalation:
May cause respiratory tract irritation. May cause methemoglobinemia,
cyanosis (bluish discoloration of skin due to deficient oxygenation
of the blood), convulsions, tachycardia, dyspnea (labored breathing),
and death. May cause liver and kidney damage. May cause cardiac
abnormalities. Inhalation at high concentrations may cause CNS
depression and asphixiation.
Chronic:
May cause methemoglobinemia, which is characterized by
chocolate-brown colored blood, headache, weakness, dizziness, breath
shortness, cyanosis (bluish skin due to deficient oxygenation of
blood), rapid heart rate, unconsciousness and possible death. Effects
may be delayed. May cause cyanosis - a blue-gray coloring of the skin
and lips caused by a lack of oxygen.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid
immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of
water for at least 15 minutes while removing contaminated clothing
and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical
aid. Get medical aid immediately. Do NOT induce vomiting. If
conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or
water. Wash mouth out with water.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If breathing is difficult, give oxygen. Do NOT use
mouth-to-mouth resuscitation. If breathing has ceased apply
artificial respiration using oxygen and a suitable mechanical device
such as a bag and a mask.
Notes to Physician:
For methemoglobinemia, administer oxygen alone or with Methylene
Blue depending on the methemoglobin concentration in the blood.
Antidote:
Methylene blue, alone or in combination with oxygen is indicated as
a treatment in nitrite induced methemoglobinemia.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. Containers
may explode when heated. Runoff from fire control or dilution water
may cause pollution.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, or water spray.
For large fires, use dry chemical, carbon dioxide, alcohol-resistant
foam, or water spray. Cool containers with flooding quantities of
water until well after fire is out.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Clean up spills immediately, observing precautions in the
Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Minimize dust generation and
accumulation. Do not breathe dust, vapor, mist, or gas. Do not get in
eyes, on skin, or on clothing. Keep container tightly closed. Avoid
ingestion and inhalation. Use only in a chemical fume hood.
Storage:
Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 1635-61-6:
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Powder
Color: yellow to orange
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 127 - 129 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: 1.22 G/L WATER (20C)
Specific Gravity/Density:
Molecular Formula: ClC6H3(NO2)NH2
Molecular Weight: 172.56
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable at room temperature in closed containers under normal storage
and handling conditions.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, strong
oxidants.
Incompatibilities with Other Materials:
Strong bases, oxidizing agents.
Hazardous Decomposition Products:
Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and
toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 1635-61-6 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
5-Chloro-2-Nitroaniline -
Not listed by ACGIH, IARC, or NTP.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: CHLORONITROANILINES
Hazard Class: 6.1
UN Number: 2237
Packing Group: III
IMO
Shipping Name: CHLORONITROANILINES
Hazard Class: 6.1
UN Number: 2237
Packing Group: III
RID/ADR
Shipping Name: CHLORONITROANILINES
Hazard Class: 6.1
UN Number: 2237
Packing group: III
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T+ N
Risk Phrases:
R 26/27/28 Very toxic by inhalation, in contact with
skin and if swallowed.
R 33 Danger of cumulative effects.
R 51/53 Toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Safety Phrases:
S 28A After contact with skin, wash immediately with
plenty of water.
S 36/37 Wear suitable protective clothing and
gloves.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 1635-61-6: 2
Canada
CAS# 1635-61-6 is listed on Canada's DSL List.
CAS# 1635-61-6 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 1635-61-6 is not listed on the TSCA inventory.
It is for research and development use only.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 9/02/1997 Revision #4 Date: 3/18/2003
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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