**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
|----------------|--------------------------------------|----------|-----------|
| 71-36-3 |N-butyl alcohol | 99.5 | 200-751-6 |
|----------------|--------------------------------------|----------|-----------|
| 485-47-2 |Ninhydrin Solution | 0.5 | 207-618-1 |
+----------------+--------------------------------------+----------+-----------+
Text for R-phrases: see Section 16
Hazard Symbols: XN
Risk Phrases: 10 22 37/38 41 67
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Flammable. Harmful if swallowed. Irritating to respiratory system
and skin. Risk of serious damage to eyes. Vapours may cause
drowsiness and dizziness.
Potential Health Effects
Eye:
Causes severe eye irritation. May cause corneal edema and
inflammation. May cause lacrimation (tearing), blurred vision, and
photophobia.
Skin:
Causes severe skin irritation. May be harmful if absorbed through
the skin. Repeated or prolonged exposure may cause drying and
cracking of the skin.
Ingestion:
Causes gastrointestinal irritation with nausea, vomiting and
diarrhea. May cause systemic toxicity with acidosis. May cause
central nervous system depression, characterized by excitement,
followed by headache, dizziness, drowsiness, and nausea. Advanced
stages may cause collapse, unconsciousness, coma and possible death
due to respiratory failure. May be harmful if swallowed. Aspiration
may be fatal. May be absorbed from the gastrointestinal tract.
Inhalation:
Causes respiratory tract irritation. May cause cardiovascular
disturbances, hearing abnormalities, central nervous system
depression, muscle weakness, and possible death due to respiratory
failure. May be absorbed through the lungs.
Chronic:
Prolonged or repeated skin contact may cause defatting and
dermatitis. May cause reproductive and fetal effects. Laboratory
experiments have resulted in mutagenic effects. Prolonged exposure
may cause liver, kidney, and heart damage. May cause damage to the
auditory nerve (some hearing loss) and vestibular injury.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid
immediately.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Wash clothing
before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4
cupfuls of milk or water. Never give anything by mouth to an
unconscious person. Possible aspiration hazard. Get medical aid
immediately. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If breathing
is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth
resuscitation. If breathing has ceased apply artificial respiration
using oxygen and a suitable mechanical device such as a bag and a
mask.
Notes to Physician:
Alcoholic beverage consumption may enhance the toxic effects of this
substance. Persons with liver, kidney, or central nervous system
diseases may be at increased risk from exposure to this product.
Butanol is especially toxic if aspirated. Treat symptomatically and
supportively.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Vapors may form an explosive mixture with air.
Vapors can travel to a source of ignition and flash back. Use water
spray to keep fire-exposed containers cool. Flammable liquid and
vapor. Vapors may be heavier than air. They can spread along the
ground and collect in low or confined areas. May be ignited by heat,
sparks, and flame. Containers may explode when heated.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or
alcohol-resistant foam. For large fires, use water spray, fog, or
alcohol-resistant foam. Use water spray to cool fire-exposed
containers. Water may be ineffective. Do NOT use straight streams of
water. Cool containers with flooding quantities of water until well
after fire is out.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Avoid runoff into storm sewers and ditches which lead to waterways.
Remove all sources of ignition. Absorb spill using an absorbent,
non-combustible material such as earth, sand, or vermiculite. Do not
use combustible materials such as sawdust. Provide ventilation. A
vapor suppressing foam may be used to reduce vapors. Water spray may
reduce vapor but may not prevent ignition in closed spaces.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use only in a well-ventilated area. Ground and
bond containers when transferring material. Use spark-proof tools and
explosion proof equipment. Avoid contact with eyes, skin, and
clothing. Empty containers retain product residue, (liquid and/or
vapor), and can be dangerous. Keep away from heat, sparks and flame.
Do not ingest or inhale. Do not pressurize, cut, weld, braze,
solder, drill, grind, or expose empty containers to heat, sparks or
open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of
ignition. Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances. Store
protected from explosives, organic peroxides, poisons, and
radioactive materials.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the
permissible exposure limits.
Exposure Limits
CAS# 71-36-3:
United Kingdom, WEL - STEL: 50 ppm STEL; 154 mg/m3 STEL
United States OSHA: 100 ppm TWA; 300 mg/m3 TWA
Belgium - TWA: 50 ppm VLE; 154 mg/m3 VLE
France - VLE: 50 ppm VLE; 150 mg/m3 VLE
Germany: 100 ppm TWA; 310 mg/m3 TWA
Japan: 50 ppm Ceiling; 150 mg/m3 Ceiling
Malaysia: 50 ppm Ceiling; 152 mg/m3 Ceiling
Netherlands: 15 ppm STEL; 45 mg/m3 STEL
Russia: 10 mg/m3 TWA
Spain: 50 ppm VLA-EC; 154 mg/m3 VLA-EC
CAS# 485-47-2:
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Liquid
Color: colorless
Odor: sweetish odor - putrid odor - fusel oil odor
pH: Not available.
Vapor Pressure: 6.5 mm Hg @ 25 deg C
Viscosity: 2.94 cP at 20 deg C
Boiling Point: 117.4 deg C
Freezing/Melting Point: -90 deg C
Autoignition Temperature: 343 deg C ( 649.40 deg F)
Flash Point: 37 deg C ( 98.60 deg F)
Explosion Limits, lower: 1.4 vol %
Explosion Limits, upper: 11.2 vol %
Decomposition Temperature: Not available.
Solubility in water: Soluble.
Specific Gravity/Density: 0.810 (Water=1)
Molecular Formula: CH3(CH2)2CH2OH
Molecular Weight: 74.0694
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, ignition sources, excess heat.
Incompatibilities with Other Materials:
Oxidizing agents, reducing agents, acid chlorides, alkali metals,
aluminum, copper, copper alloys, halogens, organic peroxides, acid
anhydrides, chromium trioxide, mineral acids.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon
dioxide.
Hazardous Polymerization: Will not occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 71-36-3: EO1400000
CAS# 485-47-2: NK5425000
LD50/LC50:
CAS# 71-36-3: Draize test, rabbit, eye: 2 mg Severe; Draize test,
rabbit, eye: 2 mg/24H Severe; Draize test, rabbit, skin: 405 mg/24H
Moderate; Draize test, rabbit, skin: 20 mg/24H Moderate; Inhalation,
rat: LC50 = 8000 ppm/4H; Inhalation, rat: LC50 = 24000 mg/m3/4H;
Oral, mouse: LD50 = 100 mg/kg; Oral, rabbit: LD50 = 3484 mg/kg;
Oral, rabbit: LD50 = 3400 mg/kg; Oral, rat: LD50 = 790 mg/kg; Oral,
rat: LD50 = 800 mg/kg; Skin, rabbit: LD50 = 3400 mg/kg.
CAS# 485-47-2.
Carcinogenicity:
N-butyl alcohol -
Not listed by ACGIH, IARC, or NTP.
Ninhydrin Solution -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Fish: Fathead Minnow: LC50 = 1510-1730 mg/L; 96 Hr; Static bioassay
at 24.7C (pH 7.64)Water flea Daphnia: EC50 = 1980-1983 mg/L; 48 Hr;
UnspecifiedBacteria: Phytobacterium phosphoreum: EC50 = 2817-3710
mg/L; 5,30 min; Microtox testRelease of n-butanol to soil may result
in volatilization from the soil surface and biodegradation is
expected to be significant. n-Butanol should not bind strongly to
soil and so is expected to leach into groundwater. Release of
n-butanol to water is expected to result in biodegradation and in
volatilization from the water surface. Photooxidation by hydroxyl
radicals is expected to be slow.
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Products which are considered hazardous for supply are classified as Special
Waste and the disposal of such chemicals is covered by regulations which may
vary according to location. Contact a specialist disposal company or the local
waste regulator for advice. Empty containers must be decontaminated before
returning for recycling.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: BUTANOL, SOLUTION
Hazard Class: 3
UN Number: 1120
Packing Group: III
IMO
Shipping Name: BUTANOL, SOLUTION
Hazard Class: 3
UN Number: 1120
Packing Group: III
RID/ADR
Shipping Name: BUTANOL, SOLUTION
Hazard Class: 3
UN Number: 1120
Packing group: III
USA RQ: CAS# 71-36-3: 5000 lb final RQ; 2270 kg final RQ
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 10 Flammable.
R 22 Harmful if swallowed.
R 37/38 Irritating to respiratory system and skin.
R 41 Risk of serious damage to eyes.
R 67 Vapours may cause drowsiness and dizziness.
Safety Phrases:
S 7/9 Keep container tightly closed and in a
well-ventilated place.
S 13 Keep away from food, drink and animal feeding
stuffs.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
S 46 If swallowed, seek medical advice immediately
and show this container or label.
WGK (Water Danger/Protection)
CAS# 71-36-3: 1
CAS# 485-47-2: 2
Canada
CAS# 71-36-3 is listed on Canada's DSL List.
CAS# 485-47-2 is listed on Canada's DSL List.
CAS# 71-36-3 is listed on Canada's Ingredient Disclosure List.
CAS# 485-47-2 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 71-36-3 is listed on the TSCA inventory.
CAS# 485-47-2 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
Text for R-phrases from Section 2
MSDS Creation Date: 6/10/1999 Revision #5 Date: 3/18/2003
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
|
|
|