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MSDS  : Toluene, 2,3-dinitro-
CAS  : 602-01-7
SYNONYMS  : * Benzene, 1-methyl-2,3-dinitro- * 2,3-Dinitrotoluene * 2,3-Dinitrotoluol * 2,3-DNT * 1-Methyl-2,3-dinitrobenzene
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : XT1400000
CHEMICAL NAME : Toluene, 2,3-dinitro-
CAS REGISTRY NUMBER : 602-01-7
BEILSTEIN REFERENCE NO. : 2212428
REFERENCE : 4-05-00-00865 (Beilstein Handbook Reference)
LAST UPDATED : 199710
DATA ITEMS CITED : 12
MOLECULAR FORMULA : C7-H6-N2-O4
MOLECULAR WEIGHT : 182.15
WISWESSER LINE NOTATION : WNR B1 FNW
COMPOUND DESCRIPTOR : Mutagen
Primary Irritant
SYNONYMS/TRADE NAMES :
* Benzene, 1-methyl-2,3-dinitro-
* 2,3-Dinitrotoluene
* 2,3-Dinitrotoluol
* 2,3-DNT
* 1-Methyl-2,3-dinitrobenzene

*** HEALTH HAZARD DATA ***

** SKIN/EYE IRRITATION DATA **

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/24H
REACTION SEVERITY : Mild
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: AD-B011-150

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 911 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: AD-A080-146

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1072 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: PB214-270

** MUTATION DATA **

TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 50 ug/plate
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For
publisher information, see EMMUEG. Volume(issue)/page/year: 4,163,1982

TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 1 mg/plate
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: AD-A080-146

TYPE OF TEST : DNA damage
TEST SYSTEM : Rodent - rat Liver
DOSE/DURATION : 300 umol/L
REFERENCE :
SinJF# Personal Communication from J.F. Sina, Merck Institute for
Therapeutic Research, West Point, PA 19486, Oct. 26, 1982
Volume(issue)/page/year: 26OCT1982

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
NIOSH REL TO 2,3-DINITROTOLUENE-air:10H CA TWA 1.5 mg/m3 (Sk)
REFERENCE :
NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
Health, Education, and Welfare, Reports and Memoranda.
Volume(issue)/page/year: DHHS #92-100,1992

*** STATUS IN U.S. ***

EPA GENETOX PROGRAM 1988, Inconclusive: CHO gene mutation

EPA TSCA Section 8(b) CHEMICAL INVENTORY

EPA TSCA Section 8(d) unpublished health/safety studies

EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

NIOSH CURRENT INTELLIGENCE BULLETIN #44


*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
Toluene, alpha-chloro-o-nitro- 612-23-7
Toluene, alpha-chloro-p-nitro- 100-14-1
Toluene, 2-chloro-4-nitro- 121-86-8
9H-Thioxanthen-9-one,1-((2-(diethylamino)ethyl)amino)-4-(hydroxymethyl)-,monomethanesulfonate (salt) 23255-93-8
Toluene, 2-chloro-6-nitro- 83-42-1
Toluene, 5-chloro-2-nitro- 5367-28-2
Toluene,4-chloro-3-nitro-alpha,alpha,alpha-trifluoro- 121-17-5
Toluene, p-chloro-alpha,alpha,alpha-trifluoro- 98-56-6
Toluene concentrate 98-56-6
Toluenediamine 25376-45-8
Toluene-2,3-diamine 2687-25-4
Toluene-2,4-diamine 95-80-7
Toluene-2,5-diamine 95-70-5
Toluene-2,6-diamine 823-40-5
Thioxanthen-9-one,1-((2-(diethylamino)ethyl)amino)-4-(hydroxymethyl)-,N-oxide 54484-90-1
Toluene-3,4-diamine 496-72-0
Toluene-2,4-diamine, N(sup 4)-acetyl-N(sup2)-trifluoromethylsulfonyl- 47000-92-0
Toluene-alpha,4-diamine, N,N-bis(2-chloroethyl)-N(supalpha),N(sup alpha)-diallyl-, dihydrochloride 47000-92-0
Toluene-alpha,3-diamine, N,N-bis(2-chloroethyl)-N(supalpha),N(sup alpha)-diallyl-, picrolonate 47000-92-0
Toluene-alpha,4-diamine, N(sup alpha),N(supalpha)-bis(2-chloroethyl)-, dihydrochloride 102395-97-1
Toluene-alpha,2-diamine, 3,5-dibromo-N(supalpha)-cyclohexyl-N-(sup alpha)-methyl-,monohydrochloride 611-75-6
Toluene-2,4-diamine, N(sup 4),N(sup4)-diethyl-3,5-dinitro-alpha,alpha,alpha-trifluoro- 29091-05-2
Toluene-2,4-diamine, dihydrochloride 636-23-7
Toluene-2,5-diamine, dihydrochloride 615-45-2
Toluene-2,6-diamine, dihydrochloride 15481-70-6
Thioxanthene-2-sulfonamide,N,N-dimethyl-9-(3-(dimethylamino)propylidene)-,hydrochloride, (E)- 25658-52-0
9H-Thioxanthen-9-one,1-((2-(diethylamino)ethyl)amino)-4-hydroxy-, 10-oxide 37599-14-7
Toluene-2,4-diamine, 5,5'-methylenebis- 97-22-3
Toluene-alpha,3-diamine,6,6'-pentamethylenedioxybis(N(sup 1),N(sup1)-diethyl-, dihydrochloride 97-22-3
Toluene-2,5-diamine, sulfate 6369-59-1
Toluene-2,5-diamine, sulfate (11) 615-50-9
Toluene-2,3-diamine, and toluene-3,4-diamine 615-50-9
Toluene-2,3-diamine, mixed with toluene-3,4-diamine(2:3) 615-50-9
o-Toluenediazonium, 5-nitro-,1,5-naphthalenedisulfonate, (1:1) sodium salt 34459-52-4
o-Toluenediazonium, 4-nitro-, tetrafluoroborate(1-) 455-90-3
p-Toluenediazonium, sulfate (11) 32066-79-8
p-Toluenediazonium, tetrafluoroborate (1-) 459-44-9
Thioxanthen-9-one,1-((2-(diethylamino)ethyl)amino)-4-methoxy- 73909-11-2
Toluene, alpha,2-dibromo-4,5-methylenedioxy- 5434-47-9
Toluene, p,alpha-dichloro- 104-83-6
Toluene, 2,4-dichloro- 95-73-8
Toluene, alpha,alpha-dichloro-alpha-fluoro- 498-67-9
Toluene, dinitro- 25321-14-6
Toluene, 2,3-dinitro- 602-01-7
Toluene, 2,4-dinitro- 121-14-2
Toluene, 2,5-dinitro- 619-15-8
Toluene, 2,6-dinitro- 606-20-2
Toluene, 3,4-dinitro- 610-39-9
Thioxanthen-9-one,1-((2-(diethylamino)ethyl)amino)-4-methyl- 479-50-5
Toluene, 3,5-dinitro- 618-85-9

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