Search   
MSDS  : Toluene, p-chloro-alpha,alpha,alpha-trifluoro-
CAS  : 98-56-6
SYNONYMS  : * Benzene, 1-chloro-4-(trifluoromethyl)- * p-Chlorobenzotrifluoride * (p-Chlorophenyl)trifluoromethane * p-Chlorotrifluoromethylbenzene * 1-Chloro-4-(trifluoromethyl)benzene * p-(Trifluoromethyl)chlorobenzene * alpha,alpha,alpha-Trifluoro-4-chlorotoluene * p-Trifluoromethylphenyl chloride
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : XS9145000
CHEMICAL NAME : Toluene, p-chloro-alpha,alpha,alpha-trifluoro-
CAS REGISTRY NUMBER : 98-56-6
OTHER CAS REGISTRY NOS. : 92709-16-5
BEILSTEIN REFERENCE NO. : 0510203
REFERENCE : 4-05-00-00815 (Beilstein Handbook Reference)
LAST UPDATED : 199712
DATA ITEMS CITED : 17
MOLECULAR FORMULA : C7-H4-Cl-F3
MOLECULAR WEIGHT : 180.56
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
SYNONYMS/TRADE NAMES :
* Benzene, 1-chloro-4-(trifluoromethyl)-
* p-Chlorobenzotrifluoride
* (p-Chlorophenyl)trifluoromethane
* p-Chlorotrifluoromethylbenzene
* 1-Chloro-4-(trifluoromethyl)benzene
* p-(Trifluoromethyl)chlorobenzene
* alpha,alpha,alpha-Trifluoro-4-chlorotoluene
* p-Trifluoromethylphenyl chloride

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 13 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year: 28(5),49,1984

TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 22 gm/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year: 28(5),49,1984

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 11500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year: 28(5),49,1984

TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 20 gm/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year: 28(5),49,1984

** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 5600 mg/kg/14D-I
TOXIC EFFECTS :
Liver - changes in liver weight
Kidney, Ureter, Bladder - changes in bladder weight
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year:
18,460,1992

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 28 gm/kg/28D-I
TOXIC EFFECTS :
Liver - changes in liver weight
Kidney, Ureter, Bladder - changes in bladder weight
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year:
25,781,1987

TYPE OF TEST : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 440 mg/m3/24H/17W-C
TOXIC EFFECTS :
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
Blood - changes in erythrocyte (RBC) count
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - true cholinesterase
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 51(10),82,1986

TYPE OF TEST : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 500 ppm/6H/4W-I
TOXIC EFFECTS :
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
Nutritional and Gross Metabolic - changes in calcium
Biochemical - Metabolism (Intermediary) - other proteins
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0570838

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 14 gm/kg/14D-I
TOXIC EFFECTS :
Liver - changes in liver weight
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
Biochemical - Metabolism (Intermediary) - lipids including transport
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year:
18,460,1992

** MUTATION DATA **

TYPE OF TEST : Unscheduled DNA synthesis
TEST SYSTEM : Human Embryo
DOSE/DURATION : 1 gm/L
REFERENCE :
AISSAW Annali dell'Istituto Superiore di Sanita. (Istituto Poligrafico e
Zecca dello Stato, Piazza Verdi, 10 Rome, Italy) V.1- 1965-
Volume(issue)/page/year: 18,123,1982

*** OCCUPATIONAL EXPOSURE LIMITS ***

OEL-RUSSIA:STEL 20 mg/m3;Skin JAN 1993

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 84021
No. of Facilities: 5 (estimated)
No. of Industries: 1
No. of Occupations: 2
No. of Employees: 20 (estimated)

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY

EPA TSCA Section 8(d) unpublished health/safety studies

EPA TSCA Section 8(e) Risk Notification, 8EHQ-0493-8771

EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

NTP Toxicity studies, RPT# TOX-14, October 1997


*** END OF RECORD ***
Search More   
ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
Toluene, alpha-chloro-o-nitro- 612-23-7
Toluene, alpha-chloro-p-nitro- 100-14-1
Toluene, 2-chloro-4-nitro- 121-86-8
9H-Thioxanthen-9-one,1-((2-(diethylamino)ethyl)amino)-4-(hydroxymethyl)-,monomethanesulfonate (salt) 23255-93-8
Toluene, 2-chloro-6-nitro- 83-42-1
Toluene, 5-chloro-2-nitro- 5367-28-2
Toluene,4-chloro-3-nitro-alpha,alpha,alpha-trifluoro- 121-17-5
Toluene, p-chloro-alpha,alpha,alpha-trifluoro- 98-56-6
Toluene concentrate 98-56-6
Toluenediamine 25376-45-8
Toluene-2,3-diamine 2687-25-4
Toluene-2,4-diamine 95-80-7
Toluene-2,5-diamine 95-70-5
Toluene-2,6-diamine 823-40-5
Thioxanthen-9-one,1-((2-(diethylamino)ethyl)amino)-4-(hydroxymethyl)-,N-oxide 54484-90-1
Toluene-3,4-diamine 496-72-0
Toluene-2,4-diamine, N(sup 4)-acetyl-N(sup2)-trifluoromethylsulfonyl- 47000-92-0
Toluene-alpha,4-diamine, N,N-bis(2-chloroethyl)-N(supalpha),N(sup alpha)-diallyl-, dihydrochloride 47000-92-0
Toluene-alpha,3-diamine, N,N-bis(2-chloroethyl)-N(supalpha),N(sup alpha)-diallyl-, picrolonate 47000-92-0
Toluene-alpha,4-diamine, N(sup alpha),N(supalpha)-bis(2-chloroethyl)-, dihydrochloride 102395-97-1
Toluene-alpha,2-diamine, 3,5-dibromo-N(supalpha)-cyclohexyl-N-(sup alpha)-methyl-,monohydrochloride 611-75-6
Toluene-2,4-diamine, N(sup 4),N(sup4)-diethyl-3,5-dinitro-alpha,alpha,alpha-trifluoro- 29091-05-2
Toluene-2,4-diamine, dihydrochloride 636-23-7
Toluene-2,5-diamine, dihydrochloride 615-45-2
Toluene-2,6-diamine, dihydrochloride 15481-70-6
Thioxanthene-2-sulfonamide,N,N-dimethyl-9-(3-(dimethylamino)propylidene)-,hydrochloride, (E)- 25658-52-0
9H-Thioxanthen-9-one,1-((2-(diethylamino)ethyl)amino)-4-hydroxy-, 10-oxide 37599-14-7
Toluene-2,4-diamine, 5,5'-methylenebis- 97-22-3
Toluene-alpha,3-diamine,6,6'-pentamethylenedioxybis(N(sup 1),N(sup1)-diethyl-, dihydrochloride 97-22-3
Toluene-2,5-diamine, sulfate 6369-59-1
Toluene-2,5-diamine, sulfate (11) 615-50-9
Toluene-2,3-diamine, and toluene-3,4-diamine 615-50-9
Toluene-2,3-diamine, mixed with toluene-3,4-diamine(2:3) 615-50-9
o-Toluenediazonium, 5-nitro-,1,5-naphthalenedisulfonate, (1:1) sodium salt 34459-52-4
o-Toluenediazonium, 4-nitro-, tetrafluoroborate(1-) 455-90-3
p-Toluenediazonium, sulfate (11) 32066-79-8
p-Toluenediazonium, tetrafluoroborate (1-) 459-44-9
Thioxanthen-9-one,1-((2-(diethylamino)ethyl)amino)-4-methoxy- 73909-11-2
Toluene, alpha,2-dibromo-4,5-methylenedioxy- 5434-47-9
Toluene, p,alpha-dichloro- 104-83-6
Toluene, 2,4-dichloro- 95-73-8
Toluene, alpha,alpha-dichloro-alpha-fluoro- 498-67-9
Toluene, dinitro- 25321-14-6
Toluene, 2,3-dinitro- 602-01-7
Toluene, 2,4-dinitro- 121-14-2
Toluene, 2,5-dinitro- 619-15-8
Toluene, 2,6-dinitro- 606-20-2
Toluene, 3,4-dinitro- 610-39-9
Thioxanthen-9-one,1-((2-(diethylamino)ethyl)amino)-4-methyl- 479-50-5
Toluene, 3,5-dinitro- 618-85-9

Free MSDS Search ( Providing 250,000+ Material Properties )
Chemcas.com| Ads link:todaystock.net