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MSDS  : Uranium, bis(nitrato)dioxo-, hexahydrate
CAS  : 13520-83-7
SYNONYMS  : * Uranium, dinitratodioxo-, hexahydrate * Uranylnitrate hexahydrate
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : YR3850000
CHEMICAL NAME : Uranium, bis(nitrato)dioxo-, hexahydrate
CAS REGISTRY NUMBER : 13520-83-7
LAST UPDATED : 199806
DATA ITEMS CITED : 29
MOLECULAR FORMULA : N2-O8-U.6H2-O
MOLECULAR WEIGHT : 502.14
WISWESSER LINE NOTATION : ONO&O-UR-O&O&ONO &QH 6
COMPOUND DESCRIPTOR : Mutagen
SYNONYMS/TRADE NAMES :
* Uranium, dinitratodioxo-, hexahydrate
* Uranylnitrate hexahydrate

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 135 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EQSSDX Environmental Quality and Safety, Supplement. (Stuttgart, Fed. Rep.
Ger.) V.1-5, 1975-76. Discontinued. Volume(issue)/page/year: 1,1,1975

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 12 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HBTXAC "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co.,
1956-59 Volume(issue)/page/year: 1,310,1955

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 6750 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EQSSDX Environmental Quality and Safety, Supplement. (Stuttgart, Fed. Rep.
Ger.) V.1-5, 1975-76. Discontinued. Volume(issue)/page/year: 1,1,1975

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : 238 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HBTXAC "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co.,
1956-59 Volume(issue)/page/year: 1,310,1955

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 630 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EQSSDX Environmental Quality and Safety, Supplement. (Stuttgart, Fed. Rep.
Ger.) V.1-5, 1975-76. Discontinued. Volume(issue)/page/year: 1,1,1975

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Bird - chicken
DOSE/DURATION : 299 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - structural or functional change in trachea
or bronchi
Liver - other changes
Kidney, Ureter, Bladder - other changes
REFERENCE :
BECTA6 Bulletin of Environmental Contamination and Toxicology.
(Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
07094) V.1- 1966- Volume(issue)/page/year: 37,907,1986

** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 200 mg/kg/29W-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
Nutritional and Gross Metabolic - weight loss or decreased weight gain
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - phosphatases
REFERENCE :
KHZDAN Khigiena i Zdraveopazvane. Hygiene and Sanitation. (Hemus, Blvd.
Russki 6, Sofia, Bulgaria) V.9- 1966- Volume(issue)/page/year:
9,142,1966

** MUTATION DATA **

TYPE OF TEST : Cytogenetic analysis
TEST SYSTEM : Rodent - hamster Lung
DOSE/DURATION : 180 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 85,288,1981

*** U.S. STANDARDS AND REGULATIONS ***

MSHA STANDARD-air:TWA 0.2 mg(U)/m3
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
3,274,1971

OSHA PEL (Gen Indu):8H TWA 0.05 mg(U)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1910.1000,1994

OSHA PEL (Construc):8H TWA 0.2 mg(U)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1926.55,1994

OSHA PEL (Shipyard):8H TWA 0.05 mg(U)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1915.1000,1993

OSHA PEL (Fed Cont):8H TWA 0.05 mg(U)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
41,50-204.50,1994

*** OCCUPATIONAL EXPOSURE LIMITS ***

OEL-AUSTRALIA:TWA 0.2 mg(U)/m3;STEL 0.6 mg(U)/m3 JAN 1993

OEL-BELGIUM:TWA 0.2 mg(U)/m3;STEL 0.5 mg(U)/m3 JAN 1993

OEL-BELGIUM:TWA 0.2 mg(U)/m3;STEL 0.6 mg(U)/m3 JAN 1993

OEL-DENMARK:TWA 0.2 mg(U)/m3 JAN 1993

OEL-FINLAND:TWA 0.2 mg(U)/m3 JAN 1993

OEL-GERMANY:TWA 0.25 mg(U)/m3 JAN 1993

OEL-THE NETHERLANDS:TWA 0.2 mg(U)/m3 JAN 1993

OEL-THE PHILIPPINES:TWA 0.05 mg(U)/m3 JAN 1993

OEL-THE PHILIPPINES:TWA 0.25 mg(U)/m3 JAN 1993

OEL-POLAND:TWA 0.015 mg(U)/m3 JAN 1993

OEL-POLAND:TWA 0.075 mg(U)/m3 JAN 1993

OEL-RUSSIA:STEL 0.015 mg(U)/m3 JAN 1993

OEL-RUSSIA:STEL 0.075 mg(U)/m3 JAN 1993

OEL-SWITZERLAND:TWA 0.2 mg(U)/m3 JAN 1993

OEL-TURKEY:TWA 0.05 mg(U)/m3 JAN 1993

OEL-UNITED KINGDOM:TWA 0.2 mg(U)/m3;STEL 0.6 mg(U)/m3 JAN 1993


*** END OF RECORD ***
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