Butanedioic acid, sulfo-, 1,4-bis(2-ethylhexyl)
ester, sodium salt, mixt. with
(2-pyridinylmethylene)di-4,1-phenylene diacetate and
rhubarb extract
CAS  
:
66813-55-6
SYNONYMS  
:
* Telemin-soft
*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : EK0120000
CHEMICAL NAME : Butanedioic acid, sulfo-, 1,4-bis(2-ethylhexyl)
ester, sodium salt, mixt. with
(2-pyridinylmethylene)di-4,1-phenylene diacetate and
rhubarb extract
CAS REGISTRY NUMBER : 66813-55-6
LAST UPDATED : 199210
DATA ITEMS CITED : 3
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Telemin-soft
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 4 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Lungs, Thorax, or Respiration - respiratory depression
Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 15,85,1978
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 4600 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Lungs, Thorax, or Respiration - respiratory depression
Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 15,85,1978
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 45 gm/kg/90D-C
TOXIC EFFECTS :
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
Nutritional and Gross Metabolic - weight loss or decreased weight gain
Related to Chronic Data - changes in testicular weight
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 15,85,1978
*** END OF RECORD ***
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