*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : GG1109000
CHEMICAL NAME : Cobalt(II) nitrate (1:2)
CAS REGISTRY NUMBER : 10141-05-6
LAST UPDATED : 199701
DATA ITEMS CITED : 13
MOLECULAR FORMULA : N2-O6.Co
MOLECULAR WEIGHT : 182.95
WISWESSER LINE NOTATION : CO N-O3*2
COMPOUND DESCRIPTOR : Tumorigen
Reproductive Effector
SYNONYMS/TRADE NAMES :
* Cobalt bis(nitrate)
* Cobalt dinitrate
* Cobalt nitrate
* Cobalt(2+) nitrate
* Cobalt(II) nitrate
* Cobaltous nitrate
* Nitric acid, cobalt(2+) salt
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 434 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Gastrointestinal - hypermotility, diarrhea
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year:
20,311,1982
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EQSSDX Environmental Quality and Safety, Supplement. (Stuttgart, Fed. Rep.
Ger.) V.1-5, 1975-76. Discontinued. Volume(issue)/page/year: 1,1,1975
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 75 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EQSSDX Environmental Quality and Safety, Supplement. (Stuttgart, Fed. Rep.
Ger.) V.1-5, 1975-76. Discontinued. Volume(issue)/page/year: 1,1,1975
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Bird - pigeon
DOSE/DURATION : 50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Amphibian - frog
DOSE/DURATION : 150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 4530 ug/kg/5D-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Tumorigenic - tumors at site of application
REFERENCE :
COREAF Comptes Rendus Hebdomadaires des Seances, Academie des Sciences.
(Paris, France) V.1-261, 1835-1965. For publisher information, see CRASEV.
Volume(issue)/page/year: 236,1387,1953
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intratesticular
SPECIES OBSERVED : Rodent - rat
DOSE : 14636 ug/kg
SEX/DURATION : male 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot,
POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960-
Volume(issue)/page/year: 7,21,1964
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE : 14636 ug/kg
SEX/DURATION : male 30 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot,
POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960-
Volume(issue)/page/year: 7,21,1964
*** REVIEWS ***
IARC Cancer Review:Human Inadequate Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 52,363,1991
IARC Cancer Review:Group 2B
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 52,363,1991
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 84330
No. of Facilities: 1152 (estimated)
No. of Industries: 18
No. of Occupations: 15
No. of Employees: 6182 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 84330
No. of Facilities: 732 (estimated)
No. of Industries: 18
No. of Occupations: 24
No. of Employees: 16243 (estimated)
No. of Female Employees: 4029 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
*** END OF RECORD ***
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| ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| | NAME | CAS |
|
Cobalt I, (dihydrogen7,12-diethyl-3,8,13,17-tetramethyl-2,18-porphinedipropionato(2-))-
| 21158-51-0 |
|
Cobalt,(ethanedioato(2-)-O,O')bis(3-methylbenzenamine)-
| 80660-64-6 |
|
C.I. Vat Brown 53
| 61902-47-4 |
|
Cobalt,(ethanedioato(2-)-O,O')bis(3-((phenylamino)methyl)-2(3H)-benzoxazolone- N(sup N(sup 3),O(sup 2))-
| 82497-97-0 |
|
Cobalt, (ethanedioato(2-)-O,O')bis(pyridine1-oxide-O)-, (T-4)-
| 74167-21-8 |
|
Cobalt(II),N,N'-ethylenebis(3-fluorosalicylideneiminato)-
| 62207-76-5 |
|
Cobalt, N,N'-ethylenebis(salicylideneiminato)-
| 14167-18-1 |
|
Cobalt(II)fluoborate
| 26490-63-1 |
|
Cobalt(II) fluoride
| 10026-17-2 |
|
Cobalt(3+), hexaammine-, (OC-6-11)-, triacetate
| 14023-85-9 |
|
Cobalt hydrocarbonyl
| 16842-03-8 |
|
Cobalt hydroxide
| 1307-86-4 |
|
Cobalt(II) hydroxide
| 21041-93-0 |
|
Citric acid, triethyl ester
| 77-93-0 |
|
Civet absolute
| 68916-26-7 |
|
Cobalt hydroxide oxide
| 12016-80-7 |
|
Cobalt, complex with niacinamide
| 12016-80-7 |
|
Cobalt(II) nitrate (12)
| 10141-05-6 |
|
Cobalt oxide (Co3O4)
| 1308-06-1 |
|
Cobalt(2+) oxide
| 1307-96-6 |
|
Cobalt(III) oxide
| 1308-04-9 |
|
Cobalt(II) perchlorate, hexahydrate
| 13478-33-6 |
|
Cobalt(II) sulfate (11)
| 10124-43-3 |
|
Cobalt(II) sulfate (11), heptahydrate
| 10026-24-1 |
|
Cobalt sulfide
| 12013-10-4 |
|
Cladomycin
| 100927-16-0 |
|
Cobalt(2+) sulfide
| 1317-42-6 |
|
Cobalt, triammine(2-oxopentanedioato(2-)-O(sup1),O(sup 2),O(sup 5))-
| 132829-10-8 |
|
Cobalt, tri-mu-carbonylnonacarbonyltetra-,tetrahydro-
| 17786-31-1 |
|
Cobalt(3+), tris(2,2'-bipyridine-N,N')-, perchlorate(1:3), (OC-6-11)-
| 14376-02-4 |
|
Cobalt(2+), tris(1,2-ethanediamine-N,N')-,(OC-6-11)-, (T-4)-tetraoxotungstate(2-) (1:1),pentahydrate
| 80669-48-3 |
|
Cobalt, tris(octamethylpyrophosphoramide)-,diperchlorate(1-)
| 80669-48-3 |
|
Cobalt(2+), tris(octamethylpyrophosphoramide)-,diperchlorate
| 26167-79-3 |
|
Cobalt(2+), tris(1,2-propanediamine-N,N')-,(T-4)-tetraoxotungstate(2-) (1:1), pentahydrate
| 80660-43-1 |
|
Cobinamide, acetate (salt) hydroxide, dihydrogenphosphate (ester), inner salt, 3'-ester with5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole
| 22465-48-1 |
|
Cobinamide, cobalt-methyl derivative, hydroxide,dihydrogen phosphate (ester), inner salt, 3'-esterwith5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole
| 13422-55-4 |
|
Clarified slurry oil
| 64741-62-4 |
|
Cobinamide, cyanide phosphate 3'-ester with5,6-dimethyl-1-alpha-D- ribofuranosylbenzimidazole,inner salt
| 68-19-9 |
|
Cobinamide, O-(5'-deoxyadenosine-5') deriv.,hydroxide, dihydrogen phosphate (ester), inner salt,3'-ester with5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole
| 13870-90-1 |
|
Cobinamide, dihydroxide, dihydrogen phosphate(ester), mono (inner salt), 3'- ester with 5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole
| 13422-51-0 |
|
Cobramin ASUBSTANCE DEFINITION :Isolated from the venom of Naja najaREFERENCE :BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House,Fairview Park, Elmsford, NY 10523) V.1- 1958-
| 13422-51-0 |
|
Cobramin B
| 12777-56-9 |
|
Cobrotoxin
| 12584-83-7 |
|
Coca leaf, extract
| 12584-83-7 |
|
Coccinia grandis (L.)Voigt, extractSUBSTANCE DEFINITION :Plant belonging to the family CucurbitaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 12584-83-7 |
|
Coccinia indica W. & A., root extractSUBSTANCE DEFINITION :Plant belonging to the family CucurbitaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 12584-83-7 |
|
Cocculus hirsutus (linn.) Diels, extract excludingrootsSUBSTANCE DEFINITION :Plant belonging to the family MenispermaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 15,208,1977
| 12584-83-7 |
|
Clary sage oil
| 8016-63-5 |
|
Cocculus laurifolius DC., extractSUBSTANCE DEFINITION :Plant belonging to the family MenispermaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 8016-63-5 |
|
Cocculus pendulus (forst) Diels, extractSUBSTANCE DEFINITION :Plant belonging to the family MenispermaceaeREFERENCE :JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. IrelandLtd., POB 85, Limerick, Ireland) V.1- 1979-
| 8016-63-5 |
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