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MSDS   | : | Colchiceine, N-deacetyl-N-methyl-
| CAS   | : | 518-11-6 | SYNONYMS   | : | * Benzo(a)heptalen-9(5H)-one,
6,7-dihydro-10-hydroxy-1,2,3-trimethoxy-7-(methylamino)-, (S)-
* Colchameine
* Demecolceine
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*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : GH0600000
CHEMICAL NAME : Colchiceine, N-deacetyl-N-methyl-
CAS REGISTRY NUMBER : 518-11-6
LAST UPDATED : 198712
DATA ITEMS CITED : 2
MOLECULAR FORMULA : C20-H23-N-O5
MOLECULAR WEIGHT : 357.44
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Benzo(a)heptalen-9(5H)-one,
6,7-dihydro-10-hydroxy-1,2,3-trimethoxy-7-(methylamino)-, (S)-
* Colchameine
* Demecolceine
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 50 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - muscle weakness
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
PHTXA6 Pharmacology and Toxicology. English translation of FATOAO. (New
York, NY) V.20-22, 1957-59. Discontinued. Volume(issue)/page/year:
20,284,1957
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 100 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - muscle weakness
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
PHTXA6 Pharmacology and Toxicology. English translation of FATOAO. (New
York, NY) V.20-22, 1957-59. Discontinued. Volume(issue)/page/year:
20,284,1957
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
Cochineal (dye)
| 1343-78-8 |
Cochlioquinone A, (8-alpha)-
| 147384-57-4 |
Coclaurine, O-demethyl-, (+-)-
| 5843-65-2 |
Cocoa fatty acids, potassium salts
| 61789-30-8 |
Coconut dimethyl amine oxide
| 61788-90-7 |
Coconut oil acid diethanolamine
| 68603-42-9 |
Coconut oil, sodium N-methyltauride salt
| 104639-43-2 |
Cocos nucifera Linn. (Dab), extractSUBSTANCE DEFINITION :Plant belonging to the family PalmaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 15,208,1977
| 104639-43-2 |
Clausena anisata Hook. f., extractSUBSTANCE DEFINITION :Plant belonging to the family RutaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 22,312,1984
| 104639-43-2 |
Codeine-B, diacetyldihydrohydroxy-
| 104639-43-2 |
Codeine B, dihydro-14-hydroxy-
| 7183-69-9 |
Codeine-C, diacetyldihydrohydroxy-
| 7183-69-9 |
Codeinone, dihydro-, hydrochloride, hydrate
| 5965-14-0 |
Codeinone, 14-hydroxy-
| 508-54-3 |
Codiaeum variegatum Blume, extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family EuphorbiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 18,594,1980
| 508-54-3 |
Codiaeum variegatum Muell. var. pictum ev. Mr.Peters, leaf extract
| 508-54-3 |
Codiocarpus andamanicus (Kurz) Howard, extractSUBSTANCE DEFINITION :Plant belonging to the family IcarinaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 28,691,1990
| 508-54-3 |
Codonopsis pilosula (franch.) nannf., extract
| 508-54-3 |
Codonopsis pilosula (Franch.) Nannf., polysaccharide
| 508-54-3 |
Clausena heptaphylla Wt. & Arn., extract excludingrootsSUBSTANCE DEFINITION :Plant belonging to the family RutaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 22,312,1984
| 508-54-3 |
Coed crude
| 508-54-3 |
Coelicolorin
| 1403-39-0 |
Coelogyne corymbros Lindl., extractSUBSTANCE DEFINITION :Indian plant belonging to the family OrchidaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 26,883,1988
| 1403-39-0 |
Coelogyne cristata Lindl., extractSUBSTANCE DEFINITION :Plant belonging to the family OrchidaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 22,312,1984
| 1403-39-0 |
Coelogyne ochracea Lindl., extractSUBSTANCE DEFINITION :Plant belonging to the family OrchidaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 1403-39-0 |
Coelogyne schultesii Jain & Das, extractSUBSTANCE DEFINITION :Plant belonging to the family OrchidaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 28,619,1990
| 1403-39-0 |
Coelogyne strict (D.Don)Schult., extractSUBSTANCE DEFINITION :Indian plant belonging to the family OrchidaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 1403-39-0 |
Coerulomycin
| 100927-17-1 |
Coffea arabica Linn., extract excluding roots
| 84650-00-0 |
Coffea bengalensis Roxb., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family RubiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 9,91,1971
| 84650-00-0 |
Clausena indica (Dalz.)-Oliver, extractSUBSTANCE DEFINITION :Plant belonging to the family RutaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 22,312,1984
| 84650-00-0 |
Coffee
| 84650-00-0 |
Coffee extract
| 8001-67-0 |
Coke oven emissions
| 8001-67-0 |
Colanic acid
| 9012-87-7 |
Cola nitida Schott et Endl., extractSUBSTANCE DEFINITION :Plant belonging to the family SterculiaceaeREFERENCE :CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA,1255 Howard St., San Francisco, CA 94103) V.6- 1958-Volume(issue)/page/year: 13,882,1965
| 9012-87-7 |
Cola nitida, nut extract
| 9012-87-7 |
Colchiceine
| 477-27-0 |
Colchiceine, N-deacetyl-N-benzoyl-
| 14686-58-9 |
Colchiceine, N-deacetyl-N-methyl-
| 518-11-6 |
Colchicine
| 64-86-8 |
Clausena indica Oliver, extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family RutaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 64-86-8 |
Colchicine, (+)-
| 75520-89-7 |
Colchicine, N-(p-aminobenzenesulfonyl)-N-deacetyl-
| 75520-89-7 |
Colchicine, 10-amino-10-demethoxy-
| 3123-89-5 |
Colchicine, 10-amino-10-demethoxy-, tartrate
| 3123-89-5 |
Colchicine,N-arabinosyl-N-deacetyl-10-demethoxy-10-(methylthio)-
| 3123-89-5 |
Colchicine, 17-chloro-
| 26279-89-0 |
Colchicine, N-deacetyl-
| 3476-50-4 |
Colchicine, N-deacetyl-N-benzoyl-
| 63989-75-3 |
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