Search   
MSDS  : Colchicine, N-deacetyl-N-formyl-
CAS  : 7411-12-3
SYNONYMS  : * N-Deacetyl-N-formylcolchicine * Formamide, N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S)- * N-Formyldeacetylcolchicine * N-Formyldesacetylcolchicine * Gloriosine
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : GH0794000
CHEMICAL NAME : Colchicine, N-deacetyl-N-formyl-
CAS REGISTRY NUMBER : 7411-12-3
BEILSTEIN REFERENCE NO. : 2824080
REFERENCE : 4-14-00-00942 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 4
MOLECULAR FORMULA : C21-H23-N-O6
MOLECULAR WEIGHT : 385.45
WISWESSER LINE NOTATION : L B677 MV&T&J CO1 DO1 EO1 JMVH NO1
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* N-Deacetyl-N-formylcolchicine
* Formamide,
N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-,
(S)-
* N-Formyldeacetylcolchicine
* N-Formyldesacetylcolchicine
* Gloriosine

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HCACAV Helvetica Chimica Acta. (Verlag Helvetica Chimica Acta, Postfach,
CH-4002 Basel, Switzerland) V.1- 1918- Volume(issue)/page/year:
33,1606,1950

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 4400 ug/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - muscle weakness
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
PHTXA6 Pharmacology and Toxicology. English translation of FATOAO. (New
York, NY) V.20-22, 1957-59. Discontinued. Volume(issue)/page/year:
20,284,1957

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2666 ug/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
20037) V.6- 1963- Volume(issue)/page/year: 24,636,1981

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 9200 ug/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - muscle weakness
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
PHTXA6 Pharmacology and Toxicology. English translation of FATOAO. (New
York, NY) V.20-22, 1957-59. Discontinued. Volume(issue)/page/year:
20,284,1957

*** END OF RECORD ***
Search More   
ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
Colchicine,N-deacetyl-10-demethoxy-N-(2-deoxy-erythro-pentosyl)-10-(methylthio)- 63989-75-3
Colchicine,N-deacetyl-10-demethoxy-N-galactopyranosyl-10-(methylthio)- 63989-75-3
Clausena lansium (Lour.) Skeels, extractSUBSTANCE DEFINITION :Plant belonging to the family RutaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- 63989-75-3
Colchicine,N-deacetyl-10-demethoxy-N-glucopyranosyl-10-(methylthio)- 63989-75-3
Colchicine,N-deacetyl-10-demethoxy-N-lyxosyl-10-(methylthio)- 63989-75-3
Colchicine,N-deacetyl-10-demethoxy-10-(methylthio)-N-ribosyl- 63989-75-3
Colchicine,N-deacetyl-10-demethoxy-10-(methylthio)-N-xylosyl- 63989-75-3
Colchicine, N-deacetyl-N,N-dimethyl- 7336-44-9
Colchicine, N-deacetyl-N-formyl- 7411-12-3
Colchicine, N-deacetyl-N-formyl-N-methyl- 14686-61-4
Colchicine, N-deacetyl-N-formyl-10-thio- 2731-23-9
Colchicine, N-deacetyl-N-methyl- 477-30-5
Colchicine, N-deacetyl-N-(p-nitrobenzoyl)- 76129-13-0
Clausena pentaphylla (roxb.) DC., extract excludingrootsSUBSTANCE DEFINITION :Plant belonging to the family RutaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- 76129-13-0
Colchicine, N-deacetyl-, d-tartrate 27963-65-1
Colchicine, N-deacetyl-10-thio- 2731-16-0
Colchicine, 10-demethoxy-10-(diethylamino)- 6962-03-4
Colchicine, 10-demethoxy-10-methylamino- 2826-80-4
Colchicine, 10-demethoxy-10-methylthio- 2730-71-4
Colchicine, O(sup 2)-demethyl- 7336-36-9
Colchicine, 3-O-demethyl- 7336-33-6
Colchicine, O(sup 1)-demethyl-, acetate 3306-60-3
Colchicine, O(sup 2)-demethyl-10-thio- 87424-26-8
Colchicine, 5,6-didehydrodeacetamido- 14511-67-2
Citric acid, triethyl ester, acetate 77-89-4
Clavamycin D 103059-95-6
Colchicine, 17-fluoro- 26195-68-6
Colchicine, N-methyl- 7336-40-5
Colchicine, N-methyl-17,17,17-trifluoro- 71295-35-7
Colchicine, 17,17,17-trifluoro- 26195-65-3
Colchicinic acid, trimethyl- 3482-37-9
Colchicinic acid, trimethyl-methyl ether, d-tartrate,hydrate 49720-72-1
Colchicoside 477-29-2
Colchicum luteum Baker, corm extractSUBSTANCE DEFINITION :Plant belonging to the family LiliaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- 477-29-2
Colchinol, N-acetyl- 38838-26-5
Colchinol, N-acetyl-, methyl ether 65967-01-3
Clay (kaolin) 1332-58-7
Colebrookea oppositifolia Sm., extract excludingrootsSUBSTANCE DEFINITION :Plant belonging to the family LamiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 22,312,1984 1332-58-7
Colestipol, hydrochloride 37296-80-3
Coleus amboinicus Lour., extractSUBSTANCE DEFINITION :Plant belonging to the family LabiataeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- 37296-80-3
Coleus caninus (roth) Vatke, extractSUBSTANCE DEFINITION :Plant belonging to the family LamiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- 37296-80-3
Coleus forskohlii Brig., root extractSUBSTANCE DEFINITION :Plant belonging to the family LabiataeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- 37296-80-3
Colisan 11051-89-1
Colistin 1066-17-7
Colistin A 7722-44-3
Colistinmethanesulfonic acid, sodium salt 8068-28-8
Collagen, pyrolyzate 8068-28-8
Clazamycin 90092-49-2
Colocasia affinis Schott, extractSUBSTANCE DEFINITION :Plant belonging to the family AraceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 28,619,1990 90092-49-2
Colocasia nymphaeifolia Kunth, leaf extractSUBSTANCE DEFINITION :Plant belonging to the family AraceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 18,594,1980 90092-49-2

Free MSDS Search ( Providing 250,000+ Material Properties )
Chemcas.com| Ads link:todaystock.net