*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : ST2100000
CHEMICAL NAME : p-Phenylenediamine, N,N'-(di-2-naphthyl)-
CAS REGISTRY NUMBER : 93-46-9
BEILSTEIN REFERENCE NO. : 2224419
REFERENCE : 4-13-00-00119 (Beilstein Handbook Reference)
LAST UPDATED : 199701
DATA ITEMS CITED : 13
MOLECULAR FORMULA : C26-H20-N2
MOLECULAR WEIGHT : 360.48
WISWESSER LINE NOTATION : L66J CMR DM- CL66J
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
Primary Irritant
SYNONYMS/TRADE NAMES :
* Aceto DIPP
* Agerite White
* N,N'-Bis-(2-naftyl)-p-fenylendiamin
* N,N'-Bis(2-naphthyl)-p-phenylenediamine
* Di-beta-naphthyl-p-phenyldiamine
* Di-beta-naphthyl-p-phenylenediamine
* N,N'-Di-beta-naphthyl-p-phenylenediamine
* N,N'-Di-2-naphthyl-p-phenylenediamine
* sym-Di-beta-naphthyl-p-phenylenediamine
* DNPD
* Dnpda
* Dwu-beta-naftylo-p-fenylodwuamina
* 2-Naphthyl-p-phenylenediamine
* Nonox CL
* Tisperse MB-2X
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Human
DOSE/DURATION : 500 mg/48H
REACTION SEVERITY : Mild
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine.
(Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU.
Volume(issue)/page/year: 5,311,1952
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/24H
REACTION SEVERITY : Mild
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,486,1986
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/24H
REACTION SEVERITY : Mild
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,486,1986
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 4500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IPSTB3 International Polymer Science and Technology. (Rapra Technology
Ltd., Shawbury, Shrewsbury, Shropshire SY4 4NR, UK) Volume(issue)/page/year:
3,93,1976
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 5 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Lungs, Thorax, or Respiration - acute pulmonary edema
Liver - other changes
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 31(2),25,1966
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Mammal - species unspecified
DOSE/DURATION : 4500 mg/kg
TOXIC EFFECTS :
Brain and Coverings - other degenerative changes
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine.
(Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU.
Volume(issue)/page/year: 5,311,1952
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 31 gm/kg/78W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Blood - tumors
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: PB223-159
** MUTATION DATA **
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 1 mg/plate
REFERENCE :
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E.
11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year:
19(Suppl 21),2,1992
TYPE OF TEST : Phage inhibition capacity
TEST SYSTEM : Bacteria - Escherichia coli
DOSE/DURATION : 100 mmol/L
REFERENCE :
MDMIAZ Medycyna Doswiadczalna i Mikrobiologia. For English translation, see
EXMMAV. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.1- 1949-
Volume(issue)/page/year: 31,11,1979
TYPE OF TEST : Cytogenetic analysis
TEST SYSTEM : Rodent - hamster Lung
DOSE/DURATION : 500 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 241,175,1990
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 84527
No. of Facilities: 58 (estimated)
No. of Industries: 3
No. of Occupations: 8
No. of Employees: 1677 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 84527
No. of Facilities: 216 (estimated)
No. of Industries: 5
No. of Occupations: 10
No. of Employees: 9999 (estimated)
No. of Female Employees: 2908 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
*** END OF RECORD ***
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| ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| | NAME | CAS |
|
p-Phenylenediamine, N,N-diethyl-, hydrochloride
| 2198-58-5 |
|
p-Phenylenediamine, N,N-diethyl-3-methyl-,hydrochloride
| 2051-79-8 |
|
p-Phenylenediamine, N,N-diethyl-, sulfate (11)
| 6283-63-2 |
|
p-Phenylenediamine, 2,6-difluoro-
| 3743-86-0 |
|
p-Phenylenediamine, N,N'-difurfurylidene-
| 19247-68-8 |
|
Phenol, 4-(pentachlorophenoxy)-
| 78576-72-4 |
|
m-Phenylenediamine, dihydrochloride
| 541-69-5 |
|
o-Phenylenediamine, dihydrochloride
| 615-28-1 |
|
p-Phenylenediamine, dihydrochloride
| 624-18-0 |
|
o-Phenylenediamine, N,N-dimethyl-
| 2836-03-5 |
|
p-Phenylenediamine, N,N-dimethyl-
| 99-98-9 |
|
p-Phenylenediamine, N-(1,3-dimethylbutyl)-N'-phenyl-
| 793-24-8 |
|
p-Phenylenediamine, N,N-dimethyl-, dihydrochloride
| 536-46-9 |
|
p-Phenylenediamine, N,N-dimethyl-, hemisulfate
| 60160-75-0 |
|
p-Phenylenediamine, N,N-dimethyl-, monohydrochloride
| 2052-46-2 |
|
m-Phenylenediamine,N,N-dimethyl-N'-(2-oxazolin-2-yl)-
| 101976-55-0 |
|
Phenol, pentachloro-, potassium salt
| 7778-73-6 |
|
p-Phenylenediamine,N,N-dimethyl-N'-(2-oxazolin-2-yl)-
| 101976-56-1 |
|
p-Phenylenediamine, N,N'-(di-2-naphthyl)-
| 93-46-9 |
|
m-Phenylenediamine, 2,4-dinitro-N(sup 3),N(sup3)-dipropyl-6-(trifluoromethyl)-
| 29091-21-2 |
|
p-Phenylenediamine, N,N'-diphenyl-
| 74-31-7 |
|
p-Phenylenediamine, N,N'-di-(o-tolyl)-
| 15017-02-4 |
|
m-Phenylenediamine, 4-ethoxy-
| 5862-77-1 |
|
m-Phenylenediamine, 4-ethoxy-, dihydrochloride
| 67801-06-3 |
|
m-Phenylenediamine, 4-(p-ethoxyphenylazo)-
| 94-10-0 |
|
m-Phenylenediamine, 4-((p-ethoxyphenyl)azo)-,monohydrochloride
| 2313-87-3 |
|
m-Phenylenediamine 4-ethyl-
| 1195-06-8 |
|
Phenol, pentachloro-, sodium salt
| 131-52-2 |
|
m-Phenylenediamine, 4-isopropoxy-, dihydrochloride
| 76486-07-2 |
|
p-Phenylenediamine, N-isopropyl-N'-phenyl-
| 101-72-4 |
|
o-Phenylenediamine, 4-methoxy-
| 102-51-2 |
|
p-Phenylenediamine, 2-methoxy-
| 5307-02-8 |
|
m-Phenylenediamine, 4-methoxy-, dihydrochloride
| 614-94-8 |
|
m-Phenylenediamine, 4-methoxy-, sulfate
| 39156-41-7 |
|
p-Phenylenediamine, 2-methoxy-, sulfate
| 66671-82-7 |
|
o-Phenylenediamine, N-methyl-
| 4760-34-3 |
|
p-Phenylenediamine, monohydrochloride
| 540-24-9 |
|
m-Phenylenediamine, 4-(1-naphthylazo)-
| 6416-57-5 |
|
Phenol, 3-(1-methyl-3-propyl-3-pyrrolidinyl)-,citrate
| 64047-77-4 |
|
Phenol, pentachloro-, sodium deriv mixed withtetrachlorophenol sodium deriv (4:1)
| 64047-77-4 |
|
m-Phenylenediamine, 4-nitro-
| 5131-58-8 |
|
o-Phenylenediamine, 3-nitro-
| 3694-52-8 |
|
o-Phenylenediamine, 4-nitro-
| 99-56-9 |
|
p-Phenylenediamine, 2-nitro-
| 5307-14-2 |
|
m-Phenylenediamine, 4,4'-pentamethylenedioxybis-
| 5307-14-2 |
|
o-Phenylenediamine, 4,4'-pentamethylenedioxybis-
| 109653-55-6 |
|
p-Phenylenediamine, N-phenyl-
| 101-54-2 |
|
m-Phenylenediamine, 4-(phenylazo)-
| 495-54-5 |
|
m-Phenylenediamine, 4-(phenylazo)-, hydrochloride
| 532-82-1 |
|
p-Phenylenediamine, N-phenyl-N'-cyclohexyl-
| 101-87-1 |
|
|