RTECS NUMBER : SZ6790000
CHEMICAL NAME : Phosphonic acid,
((3-(bis(2-chloroethyl)amino)-4-methylphenyl)hydroxym
ethylene)bis-
CAS REGISTRY NUMBER : 106871-13-0
LAST UPDATED : 199410
DATA ITEMS CITED : 4
MOLECULAR FORMULA : C12-H19-Cl2-N-O7-P2
MOLECULAR WEIGHT : 422.16
COMPOUND DESCRIPTOR : Mutagen
SYNONYMS/TRADE NAMES :
* 3-(Bis(2-chloroethyl)amino)-4-methylphenyl-hydroxymethanbiphosphonic acid
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 88 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
INNDDK Investigational New Drugs. The Journal of New Anticancer Agents.
Kluwer Academic Pub., POB 358, Accord Stn., Hingham, MA 02018) V.1- 1983-
Volume(issue)/page/year: 6,67,1988
** MUTATION DATA **
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 500 ug/plate
REFERENCE :
INNDDK Investigational New Drugs. The Journal of New Anticancer Agents.
Kluwer Academic Pub., POB 358, Accord Stn., Hingham, MA 02018) V.1- 1983-
Volume(issue)/page/year: 6,67,1988
TYPE OF TEST : DNA damage
TEST SYSTEM : Rodent - rat Liver
DOSE/DURATION : 1250 ug/tube
REFERENCE :
INNDDK Investigational New Drugs. The Journal of New Anticancer Agents.
Kluwer Academic Pub., POB 358, Accord Stn., Hingham, MA 02018) V.1- 1983-
Volume(issue)/page/year: 6,67,1988
TYPE OF TEST : DNA damage
TEST SYSTEM : Rodent - hamster Embryo
DOSE/DURATION : 1250 ug/plate
REFERENCE :
INNDDK Investigational New Drugs. The Journal of New Anticancer Agents.
Kluwer Academic Pub., POB 358, Accord Stn., Hingham, MA 02018) V.1- 1983-
Volume(issue)/page/year: 6,67,1988
*** END OF RECORD ***
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