===================== Product Identification =====================
MSDS NAME:ATROPINE SULFATE INJECTION(FOR NERVE GAS POISONING ONLY)
NIIN:00-299-9673
MSDS Number: CCBZZ
=== Responsible Party ===
Company:ESILEDERLE GENERICS
Address:2 ESTERBROOK LANE
City:CHERRY HILL
State:NJ
ZIP:08003-4099
Country:US
Info Phone Num:800-257-8349 610-688-4400(MEDICAL)
Emergency Phone Num:800-257-8349 800-424-9300(CHEMTREC)
Preparer's Name:(COPYRIGHT 1984-1995)
CAGE:LO243
=== Contractor Identification ===
Company:AMERICAN HOME PRODUCTS CORP,WYETH-AYERST LABORATOR
Address:555 E LANCASTER AVE
City:ST. DAVIDS
State:PA
ZIP:19087
Country:US
Phone:215-971-4505
CAGE:04543
Company:ELKINS-SINN INC
Address:2 ESTERBROOK LANE
Box:City:CHERRY HILL
State:NJ
ZIP:08003-4099
Country:US
Phone:800-257-8349/609-424-3700
CAGE:51968
Company:ESILEDERLE GENERICS
Address:2 ESTERBROOK LANE
Box:City:CHERRY HILL
State:NJ
ZIP:08003-4099
Country:US
Phone:800-257-8349 610-688-4400(MEDICAL)
CAGE:LO243
Company:WYETH LABS (REPLACED BY CAGE 04543)
Box:City:PHILADELPHIA
State:PA
Country:US
CAGE:1CM35
============= Composition/Information on Ingredients =============
Name:ATROPINE SULFATE
CAS:5908-99-6
Fraction by Wt: 0.04-.1%
Other REC Limits:NONE RECOMMENDED
Name:BENZYL ALCOHOL
CAS:100-51-6
RTECS #:DN3150000
Fraction by Wt: >1%
Other REC Limits:NONE RECOMMENDED
Name:WATER
CAS:7732-18-5
RTECS #:ZC0110000
Fraction by Wt: >1%
Other REC Limits:NONE RECOMMENDED
===================== Hazards Identification =====================
LD50 LC50 Mixture:ORAL LD50 (RAT) IS 600MG/KG
Routes of Entry: Inhalation:NO Skin:NO Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:**ANTICHOLINERGIC AGENT** MODERATELY
TOXIC BY INGESTION(AFFECTS GI TRACT,CNS HEART AND EYES).MAY BE
ABSORBED BY MUCOUS MEMBRANES.HYPERSENSITIVITY REACTIONS MAY OCCUR
IN INDIVIDUALS WHICH HAVE BEEN PRE VIOUSLY EXPOSED.ONLY LIMITED
DERMAL ABSORPTION OCCURS WITH INTACT SKIN.SEE SUPPLIMENTAL.
Explanation of Carcinogenicity:THERE ARE NO INGREDIENTS ABOVE 0.1%
WHICH ARE IDENTIFIED AS CARCINOGENS BY NTP,IARC OR OSHA.
Effects of Overexposure:GENERAL(ACHOLINERGICS):PUPILS DILATE,VISION
BLURS,PHOTOPHOBIA,RISE IN INTRAOCCULAR PRESSURE,DRY
NOSE,THROAT,MOUTH,THIRST,REDUCED PULSE RATE.EYES:STINGING,DRY,ITCHY
EYES,DILATED PUPILS,EYES WHICH ARE S ENSITIVE TO
LIGHT(PHOTOPHODIA).HYPERSENSITIVITY:RASH.INGEST:FLUSHED SKIN,FACIAL
RASH,FAST PULSE,PARANOID REACTIONS.
Medical Cond Aggravated by Exposure:PERSONS WITH GLAUCOMA,IMPAIRED OR
ABSTRUCTED GASTROINTESTINAL OR GASTROURINARY SYSTEMS,CARDIAC OR
LIVER IMPAIRMENTS,HYPERTHYROIDISM,HYPERTENSION,BLONDE HAIR,LIGHT
COLORED IRIDES(IRIS).
======================= First Aid Measures =======================
First Aid:SKIN:REMOVE CONTAMINATED CLOTHING;WASH WITH SOAP OR MILD
DETERGENT AND WATER.GET MEDICAL ATTENTION.EYES:FLUSH WITH NORMAL
SALINE OR WATER FOR 15 MINUTES.GET MEDICAL ATTENTION.INHAL:GET
IMMEDIATE MEDIC AL ATTENTION.REMOVE TO FRESH AIR.GIVE OXYGEN OR
ARTIFICIAL RESPIRATION IF NEEDED.INGEST:GET PROMPT QUALIFIED
MEDICAL ATTENTION.DELAY ABSORPTION WITH ACTIVATED CHARCOAL;REMOVE
BY GASTRIC LAVAGE.SUPPL.
===================== Fire Fighting Measures =====================
Flash Point:>213F,>101C
Extinguishing Media:WATER SPRAY,DRY CHEMICAL,CARBON DIOXIDE,FOAM.FOR
LARGER FIRES USE,WATER SPRAY,FOG OR REGULAR FOAM.
Fire Fighting Procedures:USE A SELF-CONTAINED BREATHING APPARATUS AND
FULL PROTECTIVE EQUIPMENT.AVOID SPREADING BURNING LIQUID WITH WATER
STREAMS.DIKE FIRE CONTROL WATER FOR DISPOSAL.
Unusual Fire/Explosion Hazard:SLIGHT FIRE HAZARD WHEN EXPOSED TO HEAT
OR FLAMES.FIRE CONDITIONS MAY EVOLVE TOXIC FUMES.
================== Accidental Release Measures ==================
Spill Release Procedures:ELIMINATE SOURCES OF IGNITION.WATER SPRAY MAY
BE USED TO REDUCE VAPORS BUT MAY NOT PREVENT IGNITION IN CLOSED
SPACES.SOAK UP WITH A NON-COMBUSTIBLE INERT
ABSORBANT(CLAY,SAND);PLACE IN PROPER CONTAINER FOR DISPOSAL.
Neutralizing Agent:NOT APPLICABLE.
====================== Handling and Storage ======================
Handling and Storage Precautions:STORE IN A COOL,DRY,WELL-VENTILATED
PLACE.KEEP CONTAINER CLOSED WHEN NOT IN USE.KEEP AWAY FROM
HEAT,SPARKS,FLAMES AND INCOMPATIBLE MATERIALS.
Other Precautions:NONE SPECIFIED BY MANUFACTURER.
============= Exposure Controls/Personal Protection =============
Respiratory Protection:WHERE ENVIRONMENTAL CONTROLS ARE LACKING OR IN
ENCLOSED SPACES USE EITHER A SELF-CONTAINED BREATHING APPARATUS OR
A NIOSH/MSHA APPROVED RESPIRATOR FOR DUST/MIST,DEPENDING ON THE
AIRBORN CONCENTRATION.
Ventilation:LOCAL VENTILATION AT THE WORKSITE;MECHANICAL(GENERAL)
VENTILATION TO MAINTAIN TLV/PEL.
Protective Gloves:LATEX(HMIS).
Eye Protection:CHEMICAL SPLASH GOGGLES
Other Protective Equipment:PROTECTIVE CLOTHING,AS NEEDED.PROVIDE A
LOCAL EYE WASH STATION AND SAFETY SHOWER.
Work Hygienic Practices:USE REASONABLE CARE IN HANDLING THIS
PRODUCT.WASH HANDS AFTER USE AND BEFORE EATING.
Supplemental Safety and Health
HEALTH HAZARDS:AN INCREASE IN INTRAOCCULAR PRESSURE MAY OCCUR IN
PERSONS WITH OPEN-ANGLE GLAUCOMA.FIRST AID:FOLLOW WITH SALINE
CATHARSIS.ANTIDOTE(ONLY BY QUALIFIED MEDICAL PERSONNEL):1MG
PHYSOSTIGMINE SALICLATE/5ML SALINE,GIVE 5ML(IV-SLOWLY OVER 2
MINUTES),DO ELECTROCARDIOGRAPHY.TOTAL DOSE IS 6MG/30MINUTES.
================== Physical/Chemical Properties ==================
HCC:T6
pH:3-6.5
Solubility in Water:MISCIBLE
Appearance and Odor:CLEAR,COLORLESS SOLUTION.
================= Stability and Reactivity Data =================
Stability Indicator/Materials to Avoid:YES
ACIDS,BASES,OXIDIZERS.
Stability Condition to Avoid:HIGH HEAT,SOURCES OF IGNITION.
Hazardous Decomposition Products:UNSPECIFIED TOXIC OR HAZARDOUS GASES.
==================== Disposal Considerations ====================
Waste Disposal Methods:DISPOSE OF IN ACCORDANCE WITH FEDERAL,STATE AND
LOCAL REGULATIONS.
Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.
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