=====================  Product Identification  =====================

MSDS NAME:M5005, MANGANESE CHLORIDE TETRAHYDRATE INSECT CELL (SUPDAT)
NIIN:00N093248
Status Code:A
MSDS Number: CJWSJ
=== Responsible Party ===
Company:SIGMA CHEMICAL CO
Box:14508
City:ST LOUIS
State:MO
ZIP:63178
Country:US
Info Phone Num:314-771-5765
Emergency Phone Num:314-771-5765
CAGE:21076
=== Contractor Identification ===
Company:SIGMA CHEMICAL COMPANY
Address:3050 SPRUCE ST
Box:14508
City:ST LOUIS
State:MO
ZIP:63178
Country:US
Phone:314-771-5765
CAGE:21076

=============  Composition/Information on Ingredients  =============

Name:MANGANESE CHLORIDE TETRAHYDRATE  LD50: (ORAL, RAT) 1484
    MG/KG
CAS:13446-34-9
RTECS #:OO9650000
= Wt:100.

=====================  Hazards Identification  =====================

LD50 LC50 Mixture:SEE INGREDIENT
Routes of Entry: Inhalation:YES  Skin:YES  Ingestion:YES
Reports of Carcinogenicity:NTP:NO    IARC:NO	OSHA:NO
Health Hazards Acute and Chronic:ACUTE EFFECTS: HARMFUL IF SWALLOWED.
    MAY BE HARMFUL IF INHALED. MAY BE HARMFUL IF ABSORBED THROUGH THE
    SKIN. CAUSES EYE AND SKIN IRRITATION. MATERIAL IS IRRITATING TO
    MUCOUS MEMBRANES AND UPPER RESPIR ATORY TRACT. CHRONIC EFFECTS:
    LABORATORYEXPERIMENTS HAVE SHOWN MUTAGENIC EFFECTS. MEN EXPOSED TO
    MANGANESE DUSTS SHOWED A DECREASE IN FERTILITY. CHRONIC MANGANESE
    POISONING PRIMARILY INVOLVES THE CENT RAL NERVOUS SYSTEM. EARLY
    SYMPTOMS INCLUDE LANGUOR, SLEEPINESS AND WEAKNESS IN THE LEGS. A
    STOLID MASK-LIKE APPEARANCE OF THE FACE, EMOTIONAL DISTURBANCES
    SUCH AS UNCONTROLLABLE LAUGHTER AND A SPASTIC  GAIT (EFFECTS OF
    OVEREXPOSURE)
Effects of Overexposure:HEALTH HAZARDS: WITH TENDENCY TO FALL IN
    WALKING ARE FINDINGS IN MORE ADVANCED CASES. HIGH INCIDENCE OF
    PNEUMONIA HAS BEEN FOUND IN WORKERS EXPOSED TO THE DUST OR FUME OF
    SOME MANGANESE COMPOUNDS. TAR GET ORGANS: CENTRAL NERVOUS SYSTEM,
    LUNGS. TO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL AND
    TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED.
    ALSO, SEE TOXICOLOGICAL INFORMATION.

=======================  First Aid Measures  =======================

Eyes: IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES WITH COPIOUS
    AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. SKIN: IN CASE OF CONTACT,
    IMMEDIATELY WASH SKIN WITH SOAP AND COPIOUS AMOUNTS OF WATER.
    INHALATI ON: IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE
    ARTIFICIAL RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
    INGESTION: IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON
    IS CONSCIO US. CALL A PHYSICIAN. WASH CONTAMINATED CLOTHING BEFORE
    REUSE.

=====================  Fire Fighting Measures  =====================

Extinguishing Media:NONCOMBUSTIBLE. USE EXTINGUISHING MEDIA APPROPRIATE
    TO SURROUNDING FIRE CONDITIONS.
Fire Fighting Procedures:USE NIOSH APPROVED SCBA AND FULL PROTECTIVE
    EQUIPMENT  TO PREVENT CONTACT WITH SKIN AND EYES.
Unusual Fire/Explosion Hazard:EMITS TOXIC FUMES UNDER FIRE CONDITIONS.

==================  Accidental Release Measures  ==================

Spill Release Procedures:WEAR NIOSH APPROVED SELF-CONTAINED BREATHING
    APPARATUS, RUBBER BOOTS AND HEAVY RUBBER GLOVES. SWEEP UP, PLACE IN
    A BAG AND HOLD FOR WASTE DISPOSAL. AVOID RAISING DUST. VENTILATE
    AREA AND WASH SPILL SI TE AFTER MATERIAL PICKUP IS COMPLETE.

======================	Handling and Storage  ======================

Handling and Storage Precautions:DO NOT BREATHE DUST. DO NOT GET IN
    EYES, ON SKIN, ON CLOTHING. AVOID PROLONGED OR REPEATED EXPOSURE.
    WASH THOROUGHLY AFTER HANDLING. KEEP TIGHTLY CLOSED.

=============  Exposure Controls/Personal Protection  =============

Respiratory Protection:WEAR APPROPRIATE NIOSH APPROVED RESPIRATOR.
Ventilation:USE ONLY IN A CHEMICAL FUME HOOD.
Protective Gloves:CHEMICAL-RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:EYE WASH AND DELUGE SHOWER MEETING ANSI
    DESIGN CRITERIA . WEAR OTHER PROTECTIVE CLOTHING.
Supplemental Safety and Health
MFR'S TRADE NAME/PART NO: CULTURE TESTED. WASTE DISP METH: NEUTRALIZE
    THE SOLUTION BEFORE FLUSHING DOWN THE DRAIN. OBSERVE ALL FEDERAL,
    STATE AND LOCAL ENVIRONMENTAL REGULATIONS.

==================  Physical/Chemical Properties  ==================

Melt/Freeze Pt:=58.C, 136.4F
Spec Gravity:2.010
Appearance and Odor:PINK CRYSTALS.

=================  Stability and Reactivity Data  =================

Stability Indicator/Materials to Avoid:YES
STRONG ACIDS. REACTS VIOLENTLY WITH: SODIUM, POTASSIUM, ZINC.
Stability Condition to Avoid:PROTECT FROM MOISTURE.
Hazardous Decomposition Products:HYDROGEN CHLORIDE GAS.

===================  Toxicological Information	===================

Toxicological Information:RTECS #: OO9650000. MANGANESE (II) CHLORIDE,
    TETRAHYDRATE. TOXICITY DATA: ORL-RAT LD50: 1484 MG/KG EVHPAZ
    10,95,1975. IRP-RAT LD50: 138 MG/KG EVHPAZ 10,95,1975. PAR-RAT
    LD50: 225 MG/KG JINCAO 41,1507, 1979. IPR-MUS LD50: 144 MG/KG
    TXAPA9 63,461,1982. SCU-MUS LD50: 320 MG/KG TOLED5 69,45,1993.
    TARGET ORGAN DATA: PAPTERNAL EFFECTS (TESTES, EPIDIMYSIS, SPERM
    DUCT). MATERNAL EFFECTS (OTHER EFFECTS ON F EMALE). EFFECTS ON
    FERTILITY (POST-IMPLANTATION MORTALITY). EFFECTS ON EMBRYO OR FETUS
    (FETOTOXICITY). SPECIFIC DEVELOPMENTAL ABNORMALITIES
    (MUSCULOSKELETAL SYSTEM). ONLY SELECTED (OTHER INFO)

=====================  Ecological Information  =====================

Ecological:DATA NOT YET AVAILABLE. FED REG INFO: OSHA PEL (SHIPYARD):
    CL 5 MG(MN)/M3 CFRGBR 29,1915.1000,1993. OSHA PEL (FED CONT): CL 5
    MG(MN)/M3 CFRGBR 41,50-204.50,1994. OEL-AUSTRALIA: TWA 5 MG(MN)/M3
    JAN 199 3. OEL-BELGIUM: TWA 5 MG(MN)/M3 JAN 1993. OEL-DENMARK: TWA
    2.5 MG(MN)/M3 JAN 1993. OEL-FINLAND: TWA 2.5 MG(MN)/M3 JAN 1993.
    OEL-HUNGARY: TWA 0.3 MG(MN)/M3; STEL 0.6 MG(MN)/M3 JAN 1993.
    OEL-JAPAN: TWA  0.3 MG(MN)/M3 JAN 1993. OEL-THE NETHERLANDS: TWA 1
    MG(MN)/M3 JAN 1993. OEL-POLAND: TWA 0.3 MG(MN)/M3 JAN 1993.
    OEL-SWEDEN: TWA 1 MG(MN)/M3; STEL 2.5 MG(MN)/M3 (RESP DUST) JAN
    1993. OEL-SWEDEN: TWA 2.5  MG(MN)/M3; (TRANSPORT INFO)

====================  Disposal Considerations  ====================

Waste Disposal Methods:THIS MATERIAL SHOULD BE DISSOLVED IN 1) WATER;
    2) ACID SOLUTION OR 3) OXIDIZED TO A WATER-SOLUBLE STATE.
    PRECIPITATE THE MATERIAL AS THE SULFIDE, ADJUSTING THE PH OF THE
    SOLUTION TO 7 TO COMPLETE PREC IPITATION. FILTER THE INSOLUBLES AND
    DISPOSE OF THEM IN A HAZARDOUS-WASTE SITE. DESTROY ANY EXCESS S
    ULFIDE WITH SODIUM HYPOCHLORITE. (SUPDAT)

===================  MSDS Transport Information  ===================

Transport Information:CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION
    INFORMATION. ECOLOGICAL INFO: STEL 5 MG(MN)/M3 (TOTAL DUST) JAN
    1993. OEL-UNITED KINGDOM: TWA 5 MG(MN)/M3 JAN 1993. OEL IN
    BULGARIA, COLOMBIA, JORDAN,  KOREA CHECK ACGIH TLV. OEL IN NEW
    ZEALAND, SINGAPORE, VIETNAM CHECK ACGIH TLV. NOES 1983: HZD X4985;
    NIS 3; TNF 110; NOS 5; TNE 3297; TFE 1033. EPA GENETOX PROGRAM
    1988, POSITIVE: CELL TRANSFORM.-RLV  F344 RAT EMBRYO.

=====================  Regulatory Information  =====================

SARA Title III Information:THIS PRODUCT IS SUBJECT TO SARA SECTION 313
    REPORTING REQUIREMENTS - MANGANESE COMPOUNDS.
Federal Regulatory Information:EUROPEAN INFORMATION - CAUTION:
    SUBSTANCE NOT YET FULLY TESTED. HARMFUL. R 22 HARMFUL IF SWALLOWED.
    R 36/37/38 IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN. R 40
    POSSIBLE RISK OF IRREVERSIBLE EFFEC TS. S 26 IN CASE OF CONTACT
    WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF WATER AND SEEK MEDICAL
    ADVICE. S 36 WEAR SUITABLE PROTECTIVE CLOTHING. REVIEWS, STANDARDS
    AND REGULATIONS - OEL=MAK. ACGIH TLV-T WA 0.2 MG(MN)/M3 DTLVS
    TLV/BEI,1997. MSHA STANDARD-AIR: CL 5 MG(MN)/M3 DTLVS 3,149,1971.
    OSHA PEL (G EN INDU): CL 5 MG(MN)/M3 CFRGBR 29,1910.1000,1994. OSHA
    PEL (CONSTRUC): CL 5 MG(MN)/M3 CFRGBR 29,1926.55,1994. (ECOLOGICAL
    INFO)

=======================  Other Information  =======================

 Disclaimer (provided with this information by the compiling agencies):
 This information is formulated for use by elements of the Department
 of Defense.  The United States of America in no manner whatsoever,
 expressly or implied, warrants this information to be accurate and
 disclaims all liability for its use.  Any person utilizing this
 document should seek competent professional advice to verify and
 assume responsibility for the suitability of this information to their
 particular situation.

*** END OF RECORD ***