===================== Product Identification =====================
MSDS NAME:ZINC CHLORIDE, MOLECULAR BIOLOGY REAGENT, Z0173
NIIN:00N093225
Status Code:A
MSDS Number: CJXCD
=== Responsible Party ===
Company:SIGMA CHEMICAL CO
Box:14508
City:ST LOUIS
State:MO
ZIP:63178
Country:US
Info Phone Num:314-771-5765
Emergency Phone Num:314-771-5765
CAGE:21076
=== Contractor Identification ===
Company:SIGMA CHEMICAL COMPANY
Address:3050 SPRUCE ST
Box:14508
City:ST LOUIS
State:MO
ZIP:63178
Country:US
Phone:314-771-5765
CAGE:21076
============= Composition/Information on Ingredients =============
Name:ZINC CHLORIDE
CAS:7646-85-7
RTECS #:ZH1400000
= Wt:100.
Other REC Limits:N/K
OSHA PEL:1 MG/M3
OSHA STEL:N/K
ACGIH TLV:1 MG/M3
ACGIH STEL:2 MG/M3
EPA Rpt Qty:1000 LBS
DOT Rpt Qty:1000 LBS
===================== Hazards Identification =====================
LD50 LC50 Mixture:SEE TOXICOLOGICAL INFORMATION.
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE: HARMFUL IF SWALLOWED. MAY BE
HARMFUL IF INHALED/ABSORBED THRU SKIN. MATL IS EXTREMELY
DESTRUCTIVE TO TISS OF MUC MEMBS & UPPER RESP TRACT, EYES & SKIN.
INHAL MAY RSLT IN SPASM, INFLAMM & PULM E DEMA. SYMPS OF EXPOS MAY
INCL BURNING SENSATION, COUGHING, WHEEZING, LARYNGITIS, SHORTNESS
OF BREATH, HDCH, NAUS & VOMIT. CHRONIC: POSS RISK OF CONGENITAL
MALFORMATION IN FETUS. TO THE BEST OF MFR'S K NOWLEDGE, THE CHEM,
PHYSICAL, & TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THORO
INVESTIGATED. ADDNL INFO: ZINC CHLORIDE & ITS AQUEOUS SOLNS ARE
CORR TO EYES & SKIN. (EFTS OF OVEREXP)
Effects of Overexposure:HLTH HAZ: THEY CAUSE CONJUNCTIVITIS & CORNEAL
BURNS IN EYE & PRODUCE CHEM BURNS, PARTICULARLY ON AREAS WHERE SKIN
IS BROKEN. INGEST PRODUCES CORROSIVE ACTION TO MOUTH, THROAT &
DIGESTIVE TRACT WHICH C AN INCLUDE SYMPS OF STOMACH PAIN,
NAUS,VOMIT, BLOODY DIARRHEA, SWELLING OF THROAT, BLOOD IN URINE &
SHOCK. INHAL IRRITATES NOSE & THROAT PRODUCING COUGH, CHEST PAIN,
BLUISH SKIN, FEVER, NAUS & VOMIT, SHORTNESS OF BREATH, DIFFICULTY
IN BREATHING (ONSET MAY BE DELAYED BY SEVERAL HOURS) & PNEUMONIA.
FATALITIES HAVE OCCURRED BY INHAL & INGEST.
======================= First Aid Measures =======================
First Aid:EYES/SKIN: IMMEDIATELY FLUSH WITH COPIOUS AMOUNTS OF WATER
FOR AT LEAST 15 MINUTES, WHILE REMOVING CONTAMINATED CLOTHING AND
SHOES. ASSURE ADEQUATE FLUSHING OF THE EYES BY SEPARATING THE
EYELIDS WITH FINGERS. INHALATION: REMOVE TO FRESH AIR. IF NOT
BREATHING, GIVE ARTIFICIAL RESPIRATION. IF BREATHING IS DIFFICULT,
GIVE OXYGEN. INGESTION: WASH OUT MOUTH WITH WATER PROVIDED PERSON
IS CONSCIOUS. CALL A PHYSICIAN. WASH CONTAMINATED CLOTHING BEFORE
REUSE. DISCARD CONTAMINATED SHOES.
===================== Fire Fighting Measures =====================
Extinguishing Media:NON-COMBUSTIBLE. USE EXTINGUISHING MEDIA
APPROPRIATE TO SURROUNDING FIRE CONDITIONS.
Fire Fighting Procedures:WEAR NIOSH APPROVED SELF-CONTAINED BREATHING
APPARATUS AND FULL PROTECTIVE EQUIPMENT .
Unusual Fire/Explosion Hazard:EMITS TOXIC FUMES UNDER FIRE CONDITIONS.
================== Accidental Release Measures ==================
Spill Release Procedures:EVACUATE AREA. WEAR NIOSH APPROVED
SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY RUBBER
GLOVES. COVER WITH DRY LIME OR SODA ASH, PICK UP, KEEP IN A CLOSED
CONTAINER AND HOLD FOR WASTE DIS POSAL. VENTILATE AREA AND WASH
SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.
====================== Handling and Storage ======================
Handling and Storage Precautions:DO NOT BREATHE DUST. DO NOT GET IN
EYES, ON SKIN, ON CLOTHING. AVOID PROLONGED OR REPEATED EXPOSURE.
KEEP TIGHTLY CLOSED. STORE IN A COOL DRY PLACE.
Other Precautions:LABEL PRECAUTIONARY STATEMENTS: CORR. CAUSES BURNS.
HARMFUL IF SWALLOWED. POSS RISK OF HARM TO UNBORN CHILD. IN CASE OF
CONT W/EYES, RINSE IMMEDIATELY W/PLENTY OF WATER & SEEK MEDICAL
ADVICE. TAKE OFF IMMEDIATELY ALL CONTAMINATED CLOTHING. WEAR
SUITABLE PROTECTIVE CLOTHING, GLOVES & EYE/FACE PROT. D O NOT
BREATHE DUST.
============= Exposure Controls/Personal Protection =============
Respiratory Protection:WEAR APPROPRIATE NIOSH APPROVED RESPIRATOR.
Ventilation:USE ONLY IN A CHEMICAL FUME HOOD.
Protective Gloves:CHEMICAL-RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES AND FULL LENGTH
FACESHIELD .
Other Protective Equipment:ANSI APPROVED EMERGENCY EYEWASH AND DELUGE
SHOWER . WEAR OTHER PROTECTIVE CLOTHING.
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health
MF: CL*2ZN. EC NUMBER: 231-592-0. TOX INFO: ENDOCRINE (CHANGE IN LH,
CHANGE IN GONADOTROPINS); PATERNAL EFTS (OTHER EFTS ON MALE); EFTS
ON FERTILITY (FEMALE FERTILITY INDEX, POST-IMPLANTATION MORTALIT
Y); SPECIFIC DEVEL ABNORMS (MUSCULOSKELETAL SYS); TUMORIGENIC EFTS
(TESTICULAR TUMORS); (OTHER INFO)
================== Physical/Chemical Properties ==================
Melt/Freeze Pt:=293.C, 559.4F
Vapor Pres:1 MM @ 428C
Spec Gravity:2.910
Appearance and Odor:WHITE CRYSTALS.
================= Stability and Reactivity Data =================
Stability Indicator/Materials to Avoid:YES
STRONG OXIDIZING AGENTS.
Stability Condition to Avoid:PROTECT FROM MOISTURE.
Hazardous Decomposition Products:HYDROGEN CHLORIDE GAS, METAL OXIDES.
=================== Toxicological Information ===================
Toxicological Information:RTECS # ZH1400000 - ZINC CHLORIDE. TOXICITY
DATA: ORL-RAT LD50: 350 MG/KG; FOREAE 7, 313, 1942. IPR-RAT LD50:
58 MG/KG; VHTODE 30, 224, 1988. IVN-RAT LD50: 3690 UG/KG; INJPD2
23, 153, 1991. ORL-MUS LD 50: 329 MG/KG; INJPD2 23, 153, 1991.
IPR-MUS LD50: 24 MG/KG; TXAPA9 63, 461, 1982. SCU-MUS LD50: 330
MG/KG; OYYAA2 8, 1067, 1974. IVN-MUS LD50: 9090 UG/KG; INJPD2 23,
153, 1991. ORL-GPG LD50: 200 MG/K G; FOREAE 7, 313, 1942. TARGET
ORGAN DATA: SENSE ORGANS & SPECIAL SENSES (MIOSIS); VASCULAR (BP
ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION); LUNGS,
THORAX/RESP (DYSPNAE); GI (COLON TUMORS); (SUP DAT)
===================== Ecological Information =====================
Ecological:DATA NOT YET AVAILABLE.
==================== Disposal Considerations ====================
Waste Disposal Methods:CONTACT A LICENSED PROFESSIONAL WASTE DISPOSAL
SERVICE TO DISPOSE OF THIS MATERIAL. OBSERVE ALL FEDERAL, STATE AND
LOCAL ENVIRONMENTAL REGULATIONS.
=================== MSDS Transport Information ===================
Transport Information:CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION
INFORMATION.
===================== Regulatory Information =====================
SARA Title III Information:THIS PRODUCT IS SUBJECT TO SARA SECTION 313
REPORTING REQUIREMENTS. OTHER INFO: TWA 1 MG/M3 (FUME) JAN 1993.
OEL-AUSTRALIA, OEL-BELGIUM, OEL-UNITED KINGDOM: TWA 1 MG/M3; STEL 2
MG/M3 (FUME) JAN 1993. OEL-DENMARK: TWA 0.5 MG/M3 (FUME) JAN 1993.
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA, NEW ZEALAND, SINGAPORE, &
VIETNAM, CHECK ACGIH TLV. NIOSH REL TO ZINC CHLORIDE FUME-AIR: 10H
TWA 1 MG/M3; STEL 2 M G/M3; NIOSH* DHHS #92-100, 1992. NOHS 1974:
HZD 77150; NIS 192; TNF 20416; NOS 84; TNE 185570. NOES 1983: HZD
77150; NIS 172; TNF 22612; NOS 115; TNE 353004; TFE 87750. (STATE
REGS)
Federal Regulatory Information:EUROPEAN INFO: EC INDEX #: 030-003-00-2.
CORR. R 34: CAUSES BURNS. S 7/8: KEEP CONTR TIGHTLY CLSD & DRY. S
28: AFTER CONT W/WKIN, WASH IMMED W/PLENTY OF WATER. S 45: IN CASE
OF ACCIDENT/IF YOU FEEL UN WELL, SEEK MED ADVICE IMMED (SHOW LABEL
WHERE POSS). REVIEWS, STDS, & REGS: OEL=MAK. ACGIH TLV-STEL: 2
MG/M3, VAP; DTLVS* TLV/BEI, 1997. ACGIH YLV-TWA: 1 MG/M3, FUME;
DTLVS* TLV/BEI, 1997. EPA FIFRA 1 988 PESTICIDE SUBJECT TO
REGISTRATION/RE-REGISTRATION; FEREAC 54, 7740, 1989. MSHA
STD-AIR:TWA 1 MG/ M3 (FUME); DTLVS* 3, 283, 1971. OSHA PEL (GEN
INDU): 8H TWA 1 MG/M3, FUME; CFRGBR 29, 1910.1000, 1994. (OTHER
INFO)
State Regulatory Information:N/P -- SARA REGS: EPA GENETOX PROGRAM
1988, POS: CELL TRANSFORMATION-SA7/SHE; HOST-MEDIATED ASSAY. EPA
GENETOX PROGRAM 1988, POS: HISTIDINE REVERSION/AMES TEST. EPA
GENETOX PROGRAM 1988: NEG: IN VITRO CYTOGENETICS-HUMAN LYMPHOCYTE.
EPA GENETOX PROGRAM 1988, NEG: B SUBTILIS REC ASSAY; SPERM
MORPHOLOGY-MOUSE. EPA TSCA SECTION 8 (B) CHEMICAL INVENTORY. EPA
TSCA SECTION 8 (D) UNPUBLISHED HEALTH/SAFETY STUDIES. EPA TSCA
TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1988. OSHA ANALYTICAL
METHOD #ID-125G.
======================= Other Information =======================
Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.
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