=====================  Product Identification  =====================

MSDS NAME:METHOTREXATE SODIUM INJECTION;25MG/ML IN V1
NIIN:01-020-2367
MSDS Number: BGDYW
=== Responsible Party ===
Company:INTERNATIONAL PHARMACEUTICAL PRODUCTS,INC.
Emergency Phone Num:(714)549-3591
CAGE:0ADG7
=== Contractor Identification ===
Company:INTERNATIONAL PHARMACEUTICAL PRODUCTS INC
Address:3001 RED HILL AVE SUITE 222
Box:City:COSTA MESA
State:CA
ZIP:92626
Country:US
CAGE:0ADG7

=============  Composition/Information on Ingredients  =============

Name:METHOTREXATE SODIUM,CAS#15475-56-6
CAS:15475-56-6
RTECS #:MA1240000
Fraction by Wt: 2.6%

Name:WATER (AS THE PHARMACEUTICAL VEHICLE)
CAS:7732-18-5
RTECS #:ZC0110000

=====================  Hazards Identification  =====================

Effects of Overexposure:EYE/SKIN;INH:IRR.TO MUC.MEMBR,SEE DR;ING:HIGH
    TOX.POT.SEE DR;ANOREX;NAUSEA;VOMIT,ALLERGY;SEE SUPPL.

=======================  First Aid Measures  =======================

First Aid:EYE:FLUSH W/WTR 15MIN.SEE EYE DR;SKIN:REMOV.CLOTH.FLUSH
    W/WTR.WASH CLOTH;INH;SEE DR;ING:FOLINIC ACID RESCUE(LEVCOVORIN
    CALCIUM).SEE DR./

=====================  Fire Fighting Measures  =====================

Extinguishing Media:CO*2, FOAM, DRY CHEM & H*2O FOG.
Fire Fighting Procedures:VAP.CAN BE IRRITATING.WEAR SCBA.

==================  Accidental Release Measures  ==================

Spill Release Procedures:WEAR GLOVS,MASK.ABSORB IMM.W/CLOTH OR
    TORK-TYPE ABSORBING WTR W/CLOTH.REPEAT THIS STEP TWICE.PLACE CLOTH
    IN DOUBLE POLYETHYLENE BAG FOR CHEM.DESTRUCTION.

======================	Handling and Storage  ======================

Handling and Storage Precautions:AVOID INH.&CONTACT W/SKIN&CLOTH.HAVE
    SFTY SHOWER&EYE BATH.STORE IN COOL DRY PLACE.PROTECT CONT.FROM
    PHYS.DAMAGE.

=============  Exposure Controls/Personal Protection  =============

Respiratory Protection:DRAGER COLLOIDAL DUST FILTER.GRADE 11B,TYPE
    855SC.
Ventilation:MECH.EXHAUST REQD.
Protective Gloves:LATEX
Eye Protection:GOGGLES
Other Protective Equipment:LAB COAT OR COVERALLS W/CAP & SHOES.
Supplemental Safety and Health
MSDS DATED 06-01-86/OVEREXPSREILOCAL IRR;LG TERM:BONE
    MARR,DEPRESS;LEUKOPEN;ANAEM;THROMBOCYTOP;BLEEDING/

==================  Physical/Chemical Properties  ==================

HCC:N1
Boiling Pt:B.P. Text:212F,100C
Solubility in Water:COMPLETE
Appearance and Odor:CLEAR,YELLOW-BROWN SOLUTION,ESSENTIALLY ODORLESS.
Percent Volatiles by Volume:97.

=================  Stability and Reactivity Data  =================

5-FLUOROURACIL,STRONG ALKALIES.
Stability Condition to Avoid:LIGHT AND HEAT EXPOSURE.
Hazardous Decomposition Products:INCOMPLETELY BURNED CARBON PRODUCTS,
    CO*2, CO.

====================  Disposal Considerations  ====================

Waste Disposal Methods:1.ADJUST PH TO 2.7.WAIT 6 HRS;2.FILTER;3.ADD
    ACTIV.CHARCOAL TO FILTR.MIX 5MIN;4.FILTR&POUR IN SEWER.5.RETURN
    CONTAM.FILTER TO ORIG.BOTTLE&ADD 100ML SULFOCHROMIC AC.MIX.WAIT
    24HRS:6.ADD ICE.NEUTRALIZE	W/NOAH.7.DISPOSE OF COLD,NEUTRALZD
    SOLN.COMPLY W/R

 Disclaimer (provided with this information by the compiling agencies):
 This information is formulated for use by elements of the Department
 of Defense.  The United States of America in no manner whatsoever,
 expressly or implied, warrants this information to be accurate and
 disclaims all liability for its use.  Any person utilizing this
 document should seek competent professional advice to verify and
 assume responsibility for the suitability of this information to their
 particular situation.

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