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Material Safety Data Sheet
CHLORTETRACYCLINE HCL
1: Chemical Product and Company Identification
Product Name: CHLORTETRACYCLINE HCL
Contact information:
Catalog Code: 762210
bioWORLD
CAS#: 64-72-2
4150 Tuller Rd
Suite 228, Dublin, OH 43017, USA
RTECS: QI7800000
For information, call: 614-792-8680
TSCA: TSCA 8(b) inventory: No products were found.
Fax Number: 614-792-8685
Order Online:www.bio-world.com
CI#: Not available.
E-mail : save@bio-world.com
Synonym: Aureociclina; Aureocycline; Aureomycin hydrochloride;
Auxeomycin; Chlorotetracycline hydrochloride; Chlortetracycline
In Case of a chemical emergency, call CHEMTREC
hydrochloride; Clorotetraciclina cloridrato (Italian); Isphamycin;
(24 hours a day) at 1-800-424-9300
NSC-13252; U-6780
For non-emergency assistance,call: 1-800-860-9729
Chemical Name: Chlortetracyclie Hydrochloride
Chemical Formula: C22H23ClN2O8路HCl
2: Composition and Information on Ingredients
Composition:
Name CAS# % by Weight
CHLORTETRACYCLINE HCL 64-72-2 100
Toxicological Data on Ingredients:
LD50 (Intraperitoneal, Rat): 335 mg/kg
LD50 (Intravenous, Rat): 100 mg/kg
LD50 (Oral, Mouse): 2314 mg/kg
LD50 (Intraperitoneal, Mouse): 197 mg/kg
LD50 (Intravenous, Mouse): 100
3: Hazards Identification
Potential Acute Health Effects: Irritant.
Irritating to eyes, respiratory system and skin.
Target organ(s): Teeth. Bones.
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Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: Not available.
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Laboratory experiments have shown teratogenic effects.
DEVELOPMENTAL TOXICITY: Not available.
4: First Aid Measures
Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at
least 15 minutes. Cold water may be used. Get medical attention if irritation occurs.
Skin Contact: Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation
develops. Cold water may be used.
Serious Skin Contact: Not available.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention.
Serious Inhalation: Not available.
Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear.
Serious Ingestion: Not available.
5: Fire and Explosion Data
Flammability of the Product: Noncombustible.
Auto-Ignition Temperature: Not available.
Flash Points: 210 掳C (410 掳F).
Flammable Limits: Not available.
Product of Combustion: Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen chloride gas.
Fire Hazards in Presence of Various Substances: Slightly flammable to flammable in presence of heat.
Explosion Hazards in Presence of Various Substances:
Risks of explosion of the product in presence of mechanical impact: Not available.
Risks of explosion of the product in presence of static discharge: Not available.
Fire Fighting Media and Instructions:
SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Special Remarks on Fire Hazards: Not available.
Special Remarks on Explosion Hazards: Not available.
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6: Accidental Release Measures
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by
spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading
water on the contaminated surface and allow to evacuate through the sanitary system.
7: Handling and Storage
Precautions: Do not breathe dust. Avoid contact with eyes, skin, and clothing. Avoid prolonged or repeated exposure.
Storage: Light Sensitive. Moisture Sensitive. Store in light-resistant containers. Keep container tightly closed. Keep
container in a cool, well-ventilated area. Do not store above 4掳C (39.2掳F).
8: Exposure Controls/Personal Protection
Engineering Controls: Safety shower and eye bath. Use only in a chemical fume hood.
Personal Protection: Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or
equivalent. Gloves.
Personal Protection in Case of a Large Spill: Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained
breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient;
consult a specialist BEFORE handling this product.
Exposure Limits: Not available.
9: Physical and Chemical Properties
Physical State and Appearance: Solid. (Solidcrystalline powder.)
Odor: Odorless.
Taste: Bitter.
Molecular Weight: 515.34 g/mole
Color: Yellow.
pH(1% soln/water): Not available.
Boiling Point: Not available.
Melting Point: 210-215C
Critical Temperature: Not available.
Specific Gravity: Not available.
Vapour Pressure: Not applicable.
Vapor Density: 17.8 (Air = 1)
Volatility: Not available.
Odor Threshold: Not available.
Water/Oil Dist. Coeff: Not available.
Ionicity (in Water): Not available.
Dispersion Properties: See solubility in water.
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Solubility: Partially soluble in cold water, hot water. Insoluble in diethyl ether, acetone.
10: Stability and Reactivity Data
Stability: Stable.
Instability Temperature: Not available.
Conditions of Instability: May discolor on exposure to light.
Incompatibility with various substances: Reactive with oxidizing agents. Slightly reactive to reactive with moisture.
Corrosivity: Not available.
Special Remarks on Reactivity: Light Sensitive. Slowly affected by light. Moisture sensitive.
Special Remarks on Corrosivity: Not available.
Polymerization: Will not occur.
11:Toxicological Information
Routes of Entry: Inhalation. Ingestion.
Toxicity to Animals:
LD50 (Intraperitoneal, Rat): 335 mg/kg
LD50 (Intravenous, Rat): 100 mg/kg
LD50 (Oral, Mouse): 2314 mg/kg
LD50 (Intraperitoneal, Mouse): 197 mg/kg
LD50 (Intravenous, Mouse): 100 mg/kg
Chronic Effects on Humans: Not available.
Other Toxic Effects on Humans: Skin Contact: Causes skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: Causes eye irritation.
Inhalation: Material is irritating to mucous membranes and upperrespiratory tract. May be harmful if inhaled.
Ingestion: May be harmful if swallowed.
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans: May cause adverse reproductive effects (growth, viability) based on
animal data. Chlortetracycline is excreted into breas milk at low concentrations.
Special Remarks on other Toxic Effects on Humans: Not available.
12: Ecological Information
Ecotoxicity: Not available.
BOD5 and COD: Not available.
Product of Biodegradation: Possibly hazardous short term degradation products are not likely. However, long term
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degradation products may arise.
Toxicity of the Products of Biodegradation: The product itself and its products of degradation are not toxic.
Special Remarks on the Products of Biodegradation: Not available.
13: Disposal Considerations
Waste Disposal: Waste must be disposed of in accordance with federal, state and local environmental control regulations.
14: Transport Information
DOT Classification: Not a DOT controlled material.
Identification: Not applicable.
Special Provisions for Transport: Not applicable.
15: Other Regulatory Information
Federal and State Regulations: TSCA 8(b) inventory : No products were found.
Other Regulations: EU ADDITIONAL CLASSIFICATION
Symbol of Danger: Xi
Indication of Danger: Irritant.
R: 36/37/38
Risk Statements: Irritating to eyes, respiratory system and skin.
S: 26
Safety Statements: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Other Classifications:
WHMIS(Canada): Not controlled under WHMIS.
DSCL(EEC): R63- Possible risk of harm to the unborn child.
S36/37- Wear suitable protective clothing and gloves.
S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
HMIS(U.S.A):
Health Hazard: 2
Fire Hazard: 0
Reactivity: 0
Personal Protection: E
National Fire Protection Association (U.S.A):
Health: 2
Flammability: 0
Reactivity: 0
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Specific hazard:
Protective Equipment: Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.
Safety glasses.
16: Other Information
References: Not available.
Other Special Considerations: Not available.
Created: 01/08/2006 11:54:56 AM
Last Updated: 07/08/2006 8:59:56 AM
Disclaimer
This product is offered by bioWORLD for research, laboratory or further manufacturing use. Not for human use or
consumption.
The information above is believed to be accurate and represents the best information currently available to us. However,we
make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we
assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the
information for their particular purposes.In no event shall Bio-World.com be liable for any claims, losses, or damages of any
third party or for lost profits or any special, indirect,incidental,consequential or exemplary damages, howsoever arising,
even if Bio-World.com has been advised of the possibility of such damages.
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