MATERIAL SAFETY
DATA SHEET
Prepared to U.S. OSHA, CMA, ANSI and Canadian WHMIS Standards
1. PRODUCT AND COMPANY INFORMATION
CHEMICAL NAME; CLASS: SULFUR DIOXIDE
SYNONYMS: Bisulfite; Sulfurous Acid Anhydride; Sulfurous Anhydride; Sulfurous Oxide;
Sulfur Oxide
CHEMICAL FAMILY NAME: Inorganic Sulfur Compound
FORMULA: SO2
Document Number: 20152
PRODUCT USE: Oxidizing & reducing uses; food preservative;
chemical solvent and other analytical &
synthetic chemical uses.
MANUFACTURED/SUPPLIED FOR:
ADDRESS: 2700 Post Oak Drive
Houston, TX 77056-8229
EMERGENCY PHONE: CHEMTREC: 1-800-424-9300
BUSINESS PHONE:
General MSDS Information 1-713/896-2896
Fax on Demand: 1-800/231-1366
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SULFUR DIOXIDE - SO2 MSDS EFFECTIVE DATE: AUGUST 31, 2005
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2. HAZARD IDENTIFICATION
EMERGENCY OVERVIEW: This product is a colorless, non-flammable, toxic liquid which rapidly turns into a gas
at standard atmospheric temperatures and pressures. This product has a distinct odor similar to burning sulfur.
Sulfur dioxide is irritating to the respiratory system and to contaminated skin and eyes. Exposure to high
concentrations of this gas may be fatal. The gas reacts with water or moisture to generate sulfurous acid, which
can also be corrosive to contaminated tissue.
SYMPTOMS OF OVER-EXPOSURE BY ROUTE OF EXPOSURE: The most significant route of over-exposure for
this gas is by inhalation.
INHALATION: Exposure to Sulfur Dioxide gas in low concentrations produces an irritating effect on the mucous
membranes of the eyes, nose, throat, and lungs due to the formation of sulfurous acid when it comes into contact
with moist tissues or moist air. Acute exposure through inhalation may result in dryness and irritation of the nose and
throat, choking, coughing, and bronchospasm. Severe over-exposure may cause death through systemic acidosis,
pulmonary edema, or from respiratory arrest. High concentrations of Sulfur Dioxide gas may cause an oxygen
deficient atmosphere. Exposure to high concentrations may cause unconsciousness, and under some
circumstances, death. The symptoms associated with specific Sulfur Dioxide concentrations are as follows:
CONCENTRATION SYMPTOM(s)
1 ppm (1-6 hr duration) Reversible decrease in lung function.
5 ppm (10-30 min duration) Constriction of bronchiole tubes.
8 ppm (20 min duration) Reddening of the throat and mild nose and throat irritation.
20 ppm For most persons exposed, this level is objectionably irritating.
500 ppm At this level, Sulfur Dioxide is so objectionable, that it is difficult to inhale a single
deep breath without irritation.
At very high concentrations Sulfur Dioxide (such as produced in enclosed spaces), symptoms can include severe
airway obstruction, resulting in hypoxemia (insufficient oxygenation of the blood), pulmonary edema (a life-
threatening accumulation of fluid in the lungs) and death in minutes. The symptoms of edema can be delayed for
hours or days after the exposure. All symptoms may be aggravated by physical exertion. As a result of severe
exposures, permanent lung injury may occur.
Prolonged or repeated over-exposures may cause impaired lung function, bronchitis, hacking cough, nasal irritation
and discharge, increased fatigue, alteration in the senses of taste and smell. Repeated over exposures to Sulfur
Dioxide can also result in dental erosion and gum disorders.
SKIN and EYE CONTACT: The gas may be irritating to the skin, especially in a moist environment. Sulfur Dioxide
may react with moisture on the skin. Symptoms of skin over-exposure may include scratchiness, pain, and redness.
If Sulfur Dioxide contaminates the eyes, damage to eye tissue will result in pain, inflammation, and potentially,
blindness. Liquid Sulfur Dioxide will be very corrosive to contaminated skin and eye tissue, producing the same
symptoms as described for the gas, but with the on-set of symptoms occurring more rapidly.
Contact with the eyes, at low exposure levels (5 ppm), can cause mild irritation. At 8-12 ppm, persons experience
smarting of the eyes and lachrymation. At severe over-exposure, Sulfur Dioxide can cause corneal burns. Eye
injury from contact with liquid Sulfur Dioxide may not be immediately noticed because of the damage which can
occur to the optical nerves.
INGESTION: While ingestion is highly unlikely, ingestion of Sulfur Dioxide can damage the tissues of the mouth,
throat, esophagus, and other tissues of the digestive system. Ingestion of Sulfur Dioxide can be fatal.
Additionally, aspiration by inhalation is possible, causing chemical pneumonia or death.
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2. HAZARD IDENTIFICATION (Continued)
HEALTH EFFECTS OR RISKS FROM EXPOSURE: An Explanation in Lay Terms. Over-exposure to Sulfur
Dioxide may cause the following health effects:
ACUTE: This gas is toxic and damaging to the respiratory system, as well as contaminated skin and eyes. Over-
exposures can result in severe irritation and burns of eyes, skin, mucous membranes, and any other exposed tissue.
If inhaled, irritation of the respiratory system may occur, with coughing, and breathing difficulty. Over-exposure to
this gas may be fatal. Though unlikely to occur during occupational use, ingestion of large quantities may be fatal.
CHRONIC: Prolonged or repeated over-exposures may cause respiratory problems, bronchitis, hacking cough,
nasal irritation and discharge, increased fatigue, alteration in the senses of taste and smell. Repeated over
exposures to Sulfur Dioxide can also result in dental erosion and gum disorders.
TARGET ORGANS: Respiratory system, skin, eyes and central nervous system.
3. COMPOSITION and INFORMATION ON INGREDIENTS
CHEMICAL NAME CAS # mole % EXPOSURE LIMITS IN AIR
ACGIH OSHA
OTHER
TLV STEL PEL STEL IDLH
ppm ppm ppm ppm ppm
Sulfur Dioxide 7446-09-5 > 99.98% NIOSH REL: 2 ppm
2, A4 5 5 100
TWA; 5 ppm STEL
(Not
DFG-MAK: 2 ppm
5 (Vacated
2 (Vacated
Classifiable
TWA
1989 PEL)
1989 PEL)
as Human
Carcinogen)
Maximum Impurities < 0.02% None of the trace impurities in this product contribute significantly to the hazards
associated with the product. All hazard information pertinent to this product has been
provided in this Material Safety Data Sheet, per the requirements of the OSHA Hazard
Communication Standard (29 CFR 1910.1200) and State equivalents standards.
This material is classified as hazardous under OSHA regulations in the United States and the WHMIS
in Canada.
NE = Not Established C = Ceiling Limit See Section 16 for Definitions of Terms Used.
NOTE: all WHMIS required information is included. It is located in appropriate sections based on the ANSI Z400.1-2004 format.
4 FIRST-AID MEASURES
RESCUERS SHOULD NOT ATTEMPT TO RETRIEVE VICTIMS OF EXPOSURE TO THIS PRODUCT
WITHOUT ADEQUATE PERSONAL PROTECTIVE EQUIPMENT. At a minimum, Self-Contained
Breathing Apparatus should be worn.
Remove victim(s) to fresh air, as quickly as possible. If not breathing, give artificial respiration If breathing is difficult,
give oxygen Only trained personnel should administer supplemental oxygen.
SKIN EXPOSURE: If Sulfur Dioxide gas or liquid contaminates the skin, immediately begin decontamination with
running water. Minimum flushing is for 15 minutes. Remove exposed or contaminated clothing, taking care not to
contaminate eyes. Victim must seek immediate medical attention.
EYE EXPOSURE: If liquid is splashed into eyes, or if irritation of the eye develops after exposure to liquid or gas,
open victim's eyes while under gentle running water. Use sufficient force to open eyelids. Have victim "roll" eyes.
Minimum flushing is for 15 minutes. Seek medical assistance immediately, preferably an ophthalmologist.
Victim(s) must be taken for medical attention. Rescuers should be taken for medical attention, if necessary. Take
copy of label and MSDS to physician or other health professional with victim(s).
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5. FIRE-FIGHTING MEASURES
FLASH POINT: Not applicable.
AUTOIGNITION TEMPERATURE: Not applicable.
FLAMMABLE LIMITS (in air by volume, %):
Lower (LEL): Not applicable.
Upper (UEL): Not applicable.
FIRE EXTINGUISHING MATERIALS: Non-flammable gas. Use extinguishing media appropriate for surrounding
fire.
UNUSUAL FIRE AND EXPLOSION HAZARDS: In the event of fire, cool containers of this product with water to
prevent failure. Use a water spray or fog to reduce or direct vapors. Do not direct a water spray at the source of a
release. Water spray should be used with care. Sulfur Dioxide can react with water to form a corrosive solution of
sulfurous acid. Sulfurous acid can corrode metal and cause injury to fire-fighters.
Explosion Sensitivity to Mechanical Impact: Not sensitive.
Explosion Sensitivity to Static Discharge: Not sensitive.
SPECIAL FIRE-FIGHTING PROCEDURES: Incipient fire responders should wear eye protection. Structural fire
fighters must wear Self-Contained Breathing Apparatus and full protective equipment. Fight fires in a protected
location. Approach fire from an upwind direction, to prevent over-exposure to Sulfur Dioxide. If this product is
involved in a fire, fire run-off water should be contained to prevent possible environmental damage. If cylinders are
exposed to heat, the cylinder may rupture or burst and release the contents. It may be prudent to remove potentially
heat-exposed cylinders from the area surrounding a fire, if it is safe for fire-fighters to do so.
6. ACCIDENTAL RELEASE MEASURES
LEAK RESPONSE: Uncontrolled releases should be responded to by trained personnel using pre-planned
procedures. Proper protective equipment should be used. In case of a spill, clear the affected area, protect people,
and respond with trained personnel. Adequate fire protection must be provided.
Minimum Personal Protective Equipment should be Level B: triple-gloves (rubber gloves and nitrile gloves, over
latex gloves), chemically resistant suit and boots, hard-hat, and Self-Contained Breathing Apparatus.
Monitor the surrounding area for Sulfur Dioxide levels and for oxygen content. A colorimetric tube is available for
Sulfur Dioxide. The atmosphere must have exposure levels of Sulfur Dioxide below those listed in Section 2
(Composition and Information on Ingredients) and at least 19.5 percent oxygen before personnel can be allowed in
the area without Self-Contained Breathing Apparatus.
Attempt to close the main source valve prior to entering the area. If this does not stop the release (or if it is not
possible to reach the valve), allow the gas to release in-place or remove it to a safe area and allow the gas to be
released there. If leaking incidentally from the cylinder or its valve, contact your supplier.
THIS IS AN EXTREMELY TOXIC GAS. Protection of all personnel and the area must be maintained.
7. HANDLING AND STORAGE
WORK PRACTICES AND HYGIENE PRACTICES: Be aware of any signs of dizziness or fatigue; exposures to
fatal concentrations of this product could occur without any significant warning symptoms. Eyewash stations or
emergency showers should be available near use areas of Sulfur Dioxide.
STORAGE AND HANDLING PRACTICES: All employees who handle this material should be trained to handle it
safely. Avoid breathing the gas or sprays or mists generated by Sulfur Dioxide. Cylinders should be stored upright
and be firmly secured to prevent falling or being knocked-over. Cylinders can be stored in the open, but in such
cases, should be protected against extremes of weather and from the dampness of the ground to prevent rusting.
Cylinders should be stored in dry, well-ventilated areas away from sources of heat, ignition and direct sunlight. Keep
storage area clear of materials which can burn. Do not allow area where cylinders are stored to exceed 52掳C
(125掳F). Store containers away from heavily trafficked areas and emergency exits. Store away from process and
production areas, away from elevators, building and room exits or main aisles leading to exits. Protect cylinders
against physical damage. Use only storage containers and equipment (pipes, valves, fittings to relieve pressure,
etc.) designed for the storage of Liquid Sulfur Dioxide.
Use a check valve or other protective device in the discharge line to prevent hazardous backflow. Never tamper with
pressure relief valves and cylinders.
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7. HANDLING AND STORAGE (Continued)
Sulfur Dioxide is heavier than air. Releases of this gas will accumulate in low areas; do not store this gas below
ground level.
Use only compatible materials for cylinders, process lines, and other Sulfur Dioxide-handling equipment. Anhydrous
Sulfur Dioxide is not corrosive to steel and other common structural materials, except zinc. In the presence of
moisture, however, corrosive conditions will develop. Lead, carbon, graphite, and stainless steel, type 316 are
recommended for handling moist Sulfur Dioxide. Periodic inspections of process equipment by knowledgeable
persons should be made to ensure that the equipment is used appropriately and the system is kept in suitable
operating condition. Sulfur Dioxide emergency equipment should be available near the point of use.
鈥? Workers who handle Sulfur Dioxide should wear protective clothing, as listed in Section 8 (Exposure Controls -
Personal Protective Equipment).
鈥? Instant-acting showers should be available in the event of an emergency.
鈥? Special eye-wash fountains or similar equipment should be available for eye irrigation.
鈥? Proper respiratory protection equipment must be provided and workers using such equipment must be carefully
trained in its operation and limitations.
鈥? Precautions must always be taken to prevent suck-back of foreign materials into the cylinder by using a check-
valve, vacuum break, or trap, since suck-back may cause dangerous pressure changes within the cylinder.
Keep the smallest amount necessary on-site at any one time. Full and empty cylinders should be segregated. Use
a first-in, first-out inventory systems to prevent full containers from being stored for long periods of time.
SPECIAL PRECAUTIONS FOR HANDLING GAS CYLINDERS: Compressed gases can present significant safety
hazards. The following rules are applicable to work situations in which cylinders are being used.
Before Use: Move cylinders with a suitable hand-truck. Do not drag, slide or roll cylinders. Do not drop cylinders or
permit them to strike each other. Secure cylinders firmly. Leave the valve protection cap (where provided) in-place
until cylinder is ready for use.
During Use: Use designated CGA fittings and other support equipment. Do not use adapters. Do not heat cylinder
by any means to increase the discharge rate of the product from the cylinder. Do not use oils or grease on gas-
handling fittings or equipment. Immediately contact the supplier if there are any difficulties associated with operating
cylinder valve. Never insert an object (e.g wrench, screwdriver, pry bar, etc.) into valve cap openings. Doing so may
damage valve, causing a leak to occur. Use an adjustable strap wrench to remove over-tight or rusted caps. Never
strike an arc, on a compressed gas cylinder or make a cylinder part of and electric circuit.
After Use: Close main cylinder valve. Valves should be closed tightly. Replace valve protection cap. Mark empty
cylinders 鈥淓MPTY鈥?.
NOTE: Use only DOT or ASME code containers designed for gas storage. Close valve after each use and when
empty.
STANDARD VALVE CONNECTIONS FOR U.S. AND CANADA: Use the proper CGA connections, DO NOT
USE ADAPTERS:
THREADED: CGA 660
PIN-INDEXED YOKE: Not applicable.
ULTRA HIGH INTEGRITY: Not applicable.
PROTECTIVE PRACTICES DURING MAINTENANCE OF CONTAMINATED EQUIPMENT: Follow practices
indicated in Section 6 (Accidental Release Measures). Make certain application equipment is locked and tagged-out
safely. Always use product in areas where adequate ventilation is provided.
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8. EXPOSURE CONTROLS - PERSONAL PROTECTION
VENTILATION AND ENGINEERING CONTROLS: Use with adequate ventilation. Local exhaust ventilation is
preferred, because it prevents gas dispersion into the work place by eliminating it at its source. If appropriate, install
automatic monitoring equipment to detect the level of sulfur dioxide. Use corrosion resistant ventilation system that
is separate from other ventilation systems. While exhaust systems of this gas should be to the outside, treatment of
the exhaust should occur, to prevent environmental contamination.
RESPIRATORY PROTECTION: Maintain exposure levels of Sulfur Dioxide below the levels listed in Section 2
(Composition and Information on Ingredients) and oxygen levels above 19.5% in the workplace. Use supplied air
respiratory protection if Sulfur Dioxide levels exceed exposure limits and if oxygen level is below 19.5% or during
emergency response to a release of this product. If respiratory protection is required, follow the requirements of the
Federal OSHA Respiratory Protection Standard (29 CFR 1910.134), or equivalent State standards. The following
NIOSH recommendations for Sulfur Dioxide concentrations in air are in place.
CONCENTRATION RESPIRATORY EQUIPMENT
Up to 20 ppm Chemical cartridge respirator with cartridge(s); or SAR.
Up to 50 ppm Powered air-purifying respirator with cartridge(s); or SAR operated in
continuous-flow mode.
Up to 100 ppm Full-Facepiece chemical cartridge respirator with cartridge(s); or gas mask with
canister; or powered air-purifying respirator with a tight-fitting facepiece and
cartridge(s); or full-facepiece SCBA; or full-facepiece SAR; or SAR with a tight-
fitting facepiece operated in a continuous-flow mode.
Emergency or Planned Entry into Unknown Concentration or IDLH Conditions: Positive pressure, full-facepiece
SCBA; or positive pressure, full-facepiece SAR with an auxiliary positive pressure
SCBA.
The IDLH concentration for Sulfur Dioxide is 100 ppm.
EYE PROTECTION: Splash goggles or safety glasses, for protection from rapidly expanding gases and splashes of
Liquid Sulfur Dioxide. Additionally, face-shields should be worn if there is a potential for contact with liquid Sulfur
Dioxide.
HAND PROTECTION: Wear leather gloves when handling cylinders of this product. Wear chemically-resistant
gloves when using this gas. Butyl rubber, chlorinated polyethylene, neoprene are recommended.
BODY PROTECTION: Use body protection appropriate for task. Coveralls may be appropriate if splashes from the
liquefied gas are anticipated. Safety shoes are recommended when handling cylinders.
9. PHYSICAL and CHEMICAL PROPERTIES
LIQUID DENSITY @ 21.1掳C (70掳F) and 49.1 psia: 86.06 lbs ft3
BOILING POINT @ 1 atm: 10.0掳C (-14.0掳F)
FREEZING/MELTING POINT @ 1 atm: -75.9掳C (-104.6掳F)
SPECIFIC GRAVITY of the liquid @ 32掳F (0掳C)and 23.7 psia compared to water @ 4掳C (39.2掳F): 1.436
SPECIFIC GRAVITY of the vapor compared to air @ 0掳C (32掳F) and 1 atm: 2.2638
SOLUBILITY IN WATER vol/vol @ 25掳C (77掳F): 0.001 pH: Not applicable.
EVAPORATION RATE (nBuAc = 1): Not applicable. MOLECULAR WEIGHT: 64.06
ODOR THRESHOLD: 3 to 5 ppm (detection) EXPANSION RATIO: Not applicable.
SPECIFIC VOLUME (ft3/lb): 5.99
VAPOR PRESSURE: 34.4
COEFFICIENT WATER/OIL DISTRIBUTION: Not applicable.
APPEARANCE AND COLOR: This product is a colorless, liquefied gas. The odor for both the liquid and gas is
similar to that of burning sulfur.
HOW TO DETECT THIS SUBSTANCE (warning properties): Though the odor is extremely disagreeable, it does
not serve as a reliable warning property for Sulfur Dioxide. The odor threshold is of the same odor of magnitude as
the concentration of exposure associated with adverse health effects. In terms of leak detection, fittings and joints
can be painted with a soap solution to detect leaks, which will be indicated by a bubble formation. Wet lead acetate
paper can be used for leak detection. Additionally, leaks of Sulfur Dioxide in lines or equipment may be located by
passing a squeeze bottle of aqueous ammonia over sites of suspected leaks; dense, white fumes sill be formed near
the leaks.
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10. STABILITY and REACTIVITY
STABILITY: Normally stable gas. In some cases Sulfur Dioxide acts as both a reducing and oxidizing agent; metals
such as tin, iron and magnesium burn in Sulfur Dioxide to form mixed sulfides and oxides.
DECOMPOSITION PRODUCTS: Will react with water or, moist air to form sulfurous acid.
MATERIALS WITH WHICH SUBSTANCE IS INCOMPATIBLE: Sulfur Dioxide is not compatible with the following
materials: strong bases, strong oxidizers, powdered metals, metal oxides, interhalogens, metal acetylides, sodium
hydride, silver azide, cesium azide, fluorine, zinc, zinc compounds.
HAZARDOUS POLYMERIZATION: Will not occur.
CONDITIONS TO AVOID: Contact with moisture and incompatible materials. Avoid exposing cylinders to
extremely high temperatures, which could cause the cylinders to rupture or burst.
11. TOXICOLOGICAL INFORMATION
TOXICITY DATA: The following information is for Sulfur Dioxide.
Eye, rabbit = 6 ppm/4 hours/32 days; mild TCLo (inhalation, mouse) = 500 ppm/5 LCLo (inhalation, human) = 3000 ppm/5
effects minutes/30 weeks; equivocal tumorigenic minutes
50
Mutation in Microorganisms System Test = 10 data LC (inhalation, rat) = 2520 ppm/1 hour
50
mmol/L LCLo (inhalation, human) = 1000 ppm/10 LC (inhalation, mouse) = 3000 ppm/30
DNA damage System Test (human, minutes; pulmonary effects minutes
lymphocyte) = 5700 ppb TCLo (inhalation, human) = 3 ppm/5 days; LCLo (inhalation, guinea pig) = 1039 ppm/24
TCLo (inhalation, mouse) = 32 ppm/ 24 hours pulmonary effected hours
(female 7-28 day post); reproductive TCLo (inhalation, human) = 12 ppm/1 hour; LCLo (inhalation, frog) = 1 pph/ 15 minutes]
effects. pulmonary effects
TCLo (inhalation, mouse) = 25 ppm/7 hours
(female 6-15 days post); teratogenic
effects
EYE IRRITATION: Temporary clouding of eyes was seen in rabbits, guinea pigs, and mice exposed to 400 ppm for 4 hours. Very severe eye
injury in rabbits was produced by a 5-second exposure to a stream of pure sulfur dioxide.
SHORT-TERM INHALATION STUDIES: Most studies indicate that high concentrations of Sulfur Dioxide effect the mechanics of respiration. A
dose-related narrowing of the bronchiole tubes leading to broncho-constriction was seen in guinea pigs exposed to concentrations of 0,2-100
ppm for 1 hour. Exposure of male mice for up to 72 hours to concentrations around 10 ppm produced nasal cavity injury (runny nose, ciliary
loss, fluid accumulation, and tissue death). The effects became more severe as exposure time increased. Less severe effects were seen in
the trachea and lungs. Other studies have not been reported any effects after 1-2 hour exposures to less than 1 ppm.
LONG-TERM INHALATION STUDIES: Exposure to 5 ppm for 225 days produced pulmonary function changes in dogs. Increased swelling,
secretions, and reddening of the trachea, as well as decreased mucosal flow was seen in dogs intermittently exposed to 1 ppm for 12 months.
There was no apparent effect on pulmonary function. No adverse effects were seen in guinea pigs exposed for 22 hours day, 7 days a week,
for 52 weeks to concentrations of 0.13-5.72 ppm. No adverse effects were seen in monkeys exposed for 78 weeks to 0.14 - 1.28 ppm.
SUSPECTED CANCER AGENT: Sulfur Dioxide is not found on the following lists: FEDERAL OSHA Z LIST, NTP,
IARC, CAL/OSHA; therefore it is not considered to be, nor suspected to be a cancer-causing agent by these
agencies.
IRRITANCY OF PRODUCT: Sulfur Dioxide is irritating to the eyes, and may be irritating to the skin.
SENSITIZATION OF PRODUCT: Sulfur Dioxide is not known to cause sensitization in humans. One study
involving guinea pigs exposed to 4.3 ppm Sulfur Dioxide, 8 hours/day for 5 days enhanced an allergic reaction to
ovalbumin (a known allergen).
REPRODUCTIVE TOXICITY INFORMATION: Listed below is information concerning the effects Sulfur Dioxide on
the human reproductive system.
Mutagenicity: Sulfur Dioxide is not expected to cause mutagenic effects in humans. In both gaseous and aqueous
forms, Sulfur Dioxide gave both positive and negative results in bacterial tests. Sulfur Dioxide has induced
morphological transformation of syrian hamster embryo cells (in-vitro).
Embryotoxcity: Sulfur Dioxide is not expected to cause embryotoxic effects in humans. In studies on pregnant mice
and rabbits, slight embryotoxicity, including decreased fetal body weight, and delayed bone development occurred
when exposed to levels of 25-70 ppm during days 6-15 of pregnancy.
Teratogenicity: Sulfur Dioxide is not expected to cause teratogenic effects in humans. In studies of mice, slight
sings of fetotoxicity, including reduced birth weight and delayed righting reflex, exposed to 32-250 ppm. Mild
maternal toxicity has been reported in mice and rabbits.
Reproductive Toxicity: Sulfur Dioxide is not expected to cause adverse reproductive effects in humans.
A mutagen is a chemical which causes permanent changes to genetic material (DNA) such that the changes will propagate
through generation lines. An embryotoxin is a chemical which causes damage to a developing embryo (i.e. within the first eight
weeks of pregnancy in humans), but the damage does not propagate across generational lines. A teratogen is a chemical which
causes damage to a developing fetus, but the damage does not propagate across generational lines. A reproductive toxin is any
substance which interferes in any way with the reproductive process.
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11. TOXICOLOGICAL INFORMATION (Continued)
MEDICAL CONDITIONS AGGRAVATED BY EXPOSURE: Pre-existing respiratory conditions may be aggravated
by over-exposure to Sulfur Dioxide.
RECOMMENDATIONS TO PHYSICIANS: Treat symptoms and reduce over-exposure.
BIOLOGICAL EXPOSURE INDICES (BEIs): Currently, Biological Exposure Indices (BEIs) are not applicable for
Sulfur Dioxide.
12. ECOLOGICAL INFORMATION
ENVIRONMENTAL STABILITY: The gas will be dissipated rapidly in well-ventilated areas. Sulfur Dioxide is
extremely stable to heat (up to 2000 掳C). Complex reactions of Sulfur Dioxide occur in the atmosphere, producing
sulfates and other sulfur compounds which contribute to air pollution.
EFFECT OF MATERIAL ON PLANTS or ANIMALS: Any adverse effect on animals would be related to oxygen
deficient environments, respiratory system damage, and damage to the skin and eyes. Because Sulfur Dioxide
produces corrosive sulfurous acid upon contact with moisture, plants may be damaged or destroyed Frost may also
be produced, in the presence of rapidly-expanding gases.
EFFECT OF CHEMICAL ON AQUATIC LIFE: Sulfur Dioxide hydrolyzes to sulfurous acid solution when in contact
with water. Sulfurous acid is very soluble in water, and even low concentrations of Sulfur Dioxide or sulfurous acid
in water is detrimental to aquatic life. If a release this product occurs near a river or other body of water, the release
has the potential to kill fish and other aquatic life.
13. DISPOSAL CONSIDERATIONS
PREPARING WASTES FOR DISPOSAL: Waste disposal must be in accordance with appropriate Federal, State,
and local regulations. Return cylinders with any residual product to Air Liquide. Do not dispose of locally.
14. TRANSPORTATION INFORMATION
THIS MATERIAL IS HAZARDOUS AS DEFINED BY 49 CFR 172.101 BY THE U.S. DEPARTMENT OF
TRANSPORTATION.
PROPER SHIPPING NAME: Sulfur dioxide, liquefied
HAZARD CLASS NUMBER and DESCRIPTION: 2.3 (Poison Gas)
UN IDENTIFICATION NUMBER: UN 1079
PACKING GROUP: Not applicable.
DOT LABEL(S) REQUIRED: Poison Gas
NORTH AMERICAN EMERGENCY RESPONSE GUIDEBOOK NUMBER (1996): 125
SPECIAL PROVISION: Sulfur Dioxide is poisonous by inhalation. Shipments must be properly described as
inhalation hazards. ZONE C.
MARINE POLLUTANT: Sulfur Dioxide is not classified by the DOT as a Marine Pollutant (as defined by 49 CFR
172.101, Appendix B).
SPECIAL SHIPPING INFORMATION: Cylinders should be transported in a secure position, in a well-ventilated
vehicle. The transportation of compressed gas cylinders in automobiles or in closed-body vehicles present serious
safety hazards and should be discouraged.
NOTE: Shipment of compressed gas cylinders which have not been filled with the owners consent is a violation of
Federal law (49 CFR, Part 173.301 (b).
TRANSPORT CANADA TRANSPORTATION OF DANGEROUS GOODS REGULATIONS: THIS MATERIAL IS
CONSIDERED AS DANGEROUS GOODS. Use the above information for the preparation of Canadian Shipments.
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15. REGULATORY INFORMATION
SARA REPORTING REQUIREMENTS: Sulfur Dioxide is subject to the reporting requirements of Sections 302, 304
and 313 of Title III of the Superfund Amendments and Reauthorization Act., as follows:
COMPONENT SARA 302 SARA 304 SARA 313
Sulfur Dioxide YES YES NO
This product is subject to the reporting requirements of Sections 311 and 312 of Title III of the Superfund
Amendments and Reauthorization Act (40 CFR 370.21).
SARA THRESHOLD PLANNING QUANTITY: 500 lbs
TSCA INVENTORY STATUS: Sulfur Dioxide is listed on the TSCA Inventory.
CERCLA REPORTABLE QUANTITIES (RQ): Sulfur Dioxide is an Extremely Hazardous Substance with a 1 pound
reporting requirement.
CALIFORNIA PROPOSITION 65: Sulfur Dioxide is not on the California Proposition 65 lists.
STATE REGULATORY INFORMATION: Sulfur Dioxide is covered under the following specific State regulations:
Alaska - Designated Toxic and Hazardous Massachusetts - Substance List: Sulfur Pennsylvania - Hazardous Substance List:
Dioxide. Sulfur Dioxide.
Substances: Sulfur Dioxide.
Minnesota - List of Hazardous Substances: Rhode Island - Hazardous Substance List:
California - Permissible Exposure Limits
Sulfur Dioxide. Sulfur Dioxide.
for Chemical Contaminants: Sulfur
Missouri - Employer Information/Toxic Texas - Hazardous Substance List: Sulfur
Dioxide.
Dioxide.
Substance List: Sulfur Dioxide.
Florida - Substance List: Sulfur Dioxide.
West Virginia - Hazardous Substance List:
New Jersey - Right to Know Hazardous
Illinois - Toxic Substance List: Sulfur
Sulfur Dioxide.
Dioxide. Substance List: Sulfur Dioxide.
Wisconsin - Toxic and Hazardous
Kansas - Section 302/313 List: Sulfur North Dakota - List of Hazardous
Substances: Sulfur Dioxide.
Dioxide. Chemicals, Reportable Quantities: No.
OTHER U.S. FEDERAL REGULATIONS:
鈥? Sulfur Dioxide is subject to the reporting requirements of CFR 29 1910.1000. Sulfur Dioxide is listed on Table
Z.1.
鈥? Sulfur Dioxide does not contain any Class I or Class II ozone depleting chemicals (40 CFR part 82).
鈥? Sulfur Dioxide is subject to the reporting requirements of Section 112(r) of the Clean Air Act. The Threshold
Quantity for this gas is 5,000 pounds.
鈥? Sulfur Dioxide is listed in Appendix A as a highly hazardous chemical, per 29 CFR 1910.119: Process Safety
Management of Highly Hazardous Chemicals. The threshold quantity for Sulfur Dioxide under this regulation is
1000 lbs.
鈥? Sulfur Dioxide is listed on Table 1 as a Regulated Substance, per 40 CFR, Part 68, of the Risk Management for
Chemical Accidental Release Prevention. The basis for listing for Sulfur Dioxide is by mandate by Congress and
as an extremely hazardous substance , with a vapor pressure of 10 mm Hg or greater.
OTHER CANADIAN REGULATIONS: Sulfur Dioxide is categorized as a Controlled Product, Hazard Classes A,
D1A and D2A as per the Controlled Product Regulations.
鈥?
SULFUR DIOXIDE - SO2 MSDS EFFECTIVE DATE: AUGUST 31, 2005
PAGE 9 OF 10
16. OTHER INFORMATION
HAZARDOUS MATERIAL INFORMATION
NFPA RATING
SYSTEM
FLAMMABILITY
HEALTH 3
(BLUE)
0
0
3
HEALTH REACTIVITY
FLAMMABILITY 0
(RED)
OTHER
REACTIVITY (YELLOW) 0
PROTECTIVE EQUIPMENT H
EYES HANDS BODY
RESPIRATORY
See Section 8
For routine industrial applications
MIXTURES: When two or more gases or liquefied gases are mixed, their hazardous properties may combine to
create additional, unexpected hazards. Obtain and evaluate the safety information for each component before
you produce the mixture. Consult an Industrial Hygienist or other trained person when you make your safety
evaluation of the end product. Remember, gases and liquids have properties which can cause serious injury or
death.
Further information about Sulfur Dioxide can be found in the following pamphlets published by: Compressed Gas
Association Inc. (CGA), 4221 Walney Road 5th floor, Chantilly, VA 20151-2923. Telephone: (703) 788-2700.
P-1 鈥淪afe Handling of Compressed Gases in Containers鈥?
SB-2 "Oxygen Deficient Atmospheres"
AV-1 "Safe Handling and Storage of Compressed Gases"
鈥淗andbook of Compressed Gases鈥?
PREPARED BY: CHEMICAL SAFETY ASSOCIATES, Inc.
9163 Chesapeake Drive, San Diego, CA 92123-1002
619/565-0302
Fax on Demand: 1-800/231-1366
This Material Safety Data Sheet is offered pursuant to OSHA鈥檚 Hazard Communication Standard, 29 CFR, 1910.1200. Other government
regulations must be reviewed for applicability to this product. To the best of Air Liquide鈥檚 knowledge, the information contained herein is
reliable and accurate as of this date; however, accuracy, suitability or completeness are not guaranteed and no warranties of any type, either
express or implied, are provided. The information contained herein relates only to this specific product. If this product is combined with other
materials, all component properties must be considered. Data may be changed from time to time. Be sure to consult the latest edition.
鈥?
SULFUR DIOXIDE - SO2 MSDS EFFECTIVE DATE: AUGUST 31, 2005
PAGE 10 OF 10
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