SULFANILAMIDE Page 1 of 8
SULFANILAMIDE
MSDS Number: S7658 --- Effective Date: 12/08/96
1. Product Identification
Synonyms: Albexan; albosol; ambeside; p-aminobenzene sulfamide; sulfanilamide
purified; Bacteramid; 4-Aminobenzenesulfonamide
CAS No.: 63-74-1
Molecular Weight: 172.21
Chemical Formula: C6H8N2O2S
Product Codes: J.T. Baker: 4079, V153 Mallinckrodt: 0267, 7921
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------- ---------
Sulfanilamide, Purified 63-74-1 90 - 100% Yes
3. Hazards Identification
Emergency Overview
--------------------------
CAUTION! MAY BE HARMFUL IF SWALLOWED OR INHALED. MAY
CAUSE IRRITATION TO SKIN, EYES, AND RESPIRATORY TRACT.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
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Health Rating: 0 - None
Flammability Rating: 1 - Slight
Reactivity Rating: 1 - Slight
Contact Rating: 1 - Slight
Lab Protective Equip: GOGGLES; LAB COAT
Storage Color Code: Orange (General Storage)
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Potential Health Effects
----------------------------------
Inhalation:
May cause irritation to the respiratory tract. Symptoms may include coughing, sore
throat, labored breathing, and chest pain.
Ingestion:
Large oral doses may cause irritation to the gastrointestinal tract. Reported side effects
include nausea, vomiting, fever, cyanosis, dizziness, dermatitis, acidosis, hepatitis, and
psychosis. May affect function of bone marrow, kidneys, liver or heart.
Skin Contact:
May cause irritation with redness and pain.
Eye Contact:
May cause irritation, redness and pain.
Chronic Exposure:
No information found.
Aggravation of Pre-existing Conditions:
Hypersensitivity reactions may occur in some individuals with symptoms of skin rash,
hives, and serum sickness. Some sulfonamides may produce skeletal defects to the
unborn.
4. First Aid Measures
Inhalation:
Remove to fresh air. Get medical attention for any breathing difficulty.
Ingestion:
Give large amounts of water to drink. Never give anything by mouth to an unconscious
person. Get medical attention.
Skin Contact:
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Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated
clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get
medical attention if irritation develops.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting upper and
lower eyelids occasionally. Get medical attention if irritation persists.
5. Fire Fighting Measures
Fire:
As with most organic solids, fire is possible at elevated temperatures or by contact with
an ignition source.
Explosion:
Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition
source is a potential dust explosion hazard.
Fire Extinguishing Media:
Water spray, dry chemical, alcohol foam, or carbon dioxide.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained
breathing apparatus with full facepiece operated in the pressure demand or other positive
pressure mode.
6. Accidental Release Measures
Ventilate area of leak or spill. Wear appropriate personal protective equipment as
specified in Section 8. Spills: Sweep up and containerize for reclamation or disposal.
Vacuuming or wet sweeping may be used to avoid dust dispersal.
7. Handling and Storage
Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against
physical damage. Protect from light. Isolate from incompatible substances. Containers of
this material may be hazardous when empty since they retain product residues (dust,
solids); observe all warnings and precautions listed for the product.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
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None established.
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures as
low as possible. Local exhaust ventilation is generally preferred because it can control the
emissions of the contaminant at its source, preventing dispersion of it into the general
work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of
Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
For conditions of use where exposure to the dust or mist is apparent, a half-face dust/mist
respirator may be worn. For emergencies or instances where the exposure levels are not
known, use a full-face positive-pressure, air-supplied respirator. WARNING: Air-
purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection:
Wear protective gloves and clean body-covering clothing.
Eye Protection:
Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities in
work area.
9. Physical and Chemical Properties
Appearance:
White powder.
Odor:
Odorless.
Solubility:
7.5 gm/100gm water at 25C (77F).
Density:
1.08
pH:
(neutral to litmus)
% Volatiles by volume @ 21C (70F):
0
Boiling Point:
No information found.
Melting Point:
165C (329F)
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Vapor Density (Air=1):
No information found.
Vapor Pressure (mm Hg):
No information found.
Evaporation Rate (BuAc=1):
No information found.
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Burning may produce carbon monoxide, carbon dioxide, sulfur oxides, and nitrogen
oxides.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Strong acids and strong oxidizers.
Conditions to Avoid:
Light and incompatibles.
11. Toxicological Information
Oral rat LD50: 3900mg/kg Investigated as a tumorigen, mutagen, reproductive effector.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Sulfanilamide, Purified (63-74-1) No No None
12. Ecological Information
Environmental Fate:
No information found.
Environmental Toxicity:
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No information found.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate
and approved waste disposal facility. Processing, use or contamination of this product
may change the waste management options. State and local disposal regulations may
differ from federal disposal regulations. Dispose of container and unused contents in
accordance with federal, state and local requirements.
14. Transport Information
Not regulated.
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Sulfanilamide, Purified (63-74-1) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Sulfanilamide, Purified (63-74-1) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Sulfanilamide, Purified (63-74-1) No No No No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Sulfanilamide, Purified (63-74-1) No No No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: No Fire: No Pressure: No
Reactivity: No (Pure / Solid)
Australian Hazchem Code: No information found.
Poison Schedule: No information found.
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WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products
Regulations (CPR) and the MSDS contains all of the information required by the CPR.
16. Other Information
NFPA Ratings: Health: 1 Flammability: 1 Reactivity: 0
Label Hazard Warning:
CAUTION! MAY BE HARMFUL IF SWALLOWED OR INHALED. MAY CAUSE
IRRITATION TO SKIN, EYES, AND RESPIRATORY TRACT.
Label Precautions:
Avoid contact with eyes, skin and clothing. Avoid breathing dust. Keep container closed.
Use with adequate ventilation. Wash thoroughly after handling.
Label First Aid:
If swallowed, give large amounts of water to drink. Never give anything by mouth to an
unconscious person. Get medical attention. In case of contact, immediately flush eyes or
skin with plenty of water for at least 15 minutes. Get medical attention if irritation
develops or persists. If inhaled, remove to fresh air. Get medical attention for any
breathing difficulty.
Product Use:
Laboratory Reagent.
Revision Information:
Pure. New 16 section MSDS format, all sections have been revised.
Disclaimer:
***************************************************************************************
Mallinckrodt Baker, Inc. provides the information contained herein in good faith
but makes no representation as to its comprehensiveness or accuracy. This
document is intended only as a guide to the appropriate precautionary handling of
the material by a properly trained person using this product. Individuals receiving
the information must exercise their independent judgment in determining its
appropriateness for a particular purpose. MALLINCKRODT BAKER, INC.
MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR
IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF
MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH
RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT
TO WHICH THE INFORMATION REFERS. ACCORDINGLY,
MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR
DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS
INFORMATION.
***************************************************************************************
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Prepared by: Strategic Services Division
Phone Number: (314) 539-1600 (U.S.A.)
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