Creation Date: 03-26-2002
Revision Date: 07-23-2004
Material Safety Data Sheet
.
1. Chemical Product and Company Identification
space
Material Name 2-[125I]-Iodomelatonin
space
01
Version #
space
NEX236000MC
Item #
space
PerkinElmer Life and Analytical Sciences
Identification Of The
710 Bridgeport Avenue
Company/Undertaking
Shelton, CT 06484
space
Technical Support 800-762-4000
space
CHEMTREC 800-424-9300
Emergency Telephone
Emergency Phone 800-762-4000
Number
.
2. Composition / Information on Ingredients
space
Hazardous component(s) CAS # Percent PEL TLV
METHANOL 67-56-1 1 - 2.5 200 ppm 200
ETHANOL 64-17-5 > 90 1000 ppm 1000
space
Non-hazardous component(s) CAS # Percent
WATER 7732-18-5 1 - 2.5
2-[125I]-IODOMELATONIN 0.01 - 0.1
space
.
3. Hazards Identification
space
Emergency Overview
Highly flammable.
Harmful by inhalation, in contact with skin and if swallowed.
Irritating to eyes, respiratory system and skin.
Danger of very serious irreversible effects.
space
.
4. First Aid Measures
space
General advice
In case of feeling unwell: Call a physician immediately.
space
First Aid
Skin contact
Wash off immediately with soap and plenty of water removing all contaminated clothes and
shoes.
space
Eye contact
Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes.
space
Inhalation
Move to fresh air. Oxygen or artificial respiration if needed.
space
Ingestion
Clean mouth with water and drink afterwards plenty of water. Never give anything by mouth to
an unconscious person.
space
Material ID 4683 Material Name 2-[125I]-Iodomelatonin
1/ 5
MSDS US
.
5. Fire Fighting Measures
space
Suitable extinguishing media
water spray.
carbon dioxide (CO2), dry chemical or foam
space
Special protective equipment for firefighters
Wear suitable protective equipment
space
Unusual Fire & Explosion Hazards
In the event of fire toxic fumes may be formed.
.
6. Accidental Release Measures
space
Personal precautions
Ensure adequate ventilation. Use personal protective equipment. Remove all sources of ignition.
space
Environmental precautions
Do not contaminate water.
space
Methods for cleaning up
Soak up with inert absorbent material. Clean contaminated surface thoroughly. Keep in suitable and
closed containers for disposal.
space
.
7. Handling and Storage
space
Handling
Use only in area provided with appropriate exhaust ventilation. Wear personal protective
equipment. Do not breathe vapours or spray mist. Avoid contact with skin and eyes. Keep away
from heat and sources of ignition.
space
Storage
Keep tightly closed in a dry and cool place.
.
8. Exposure Controls / Personal Protection
space
Exposure Limit Values
space
Exposure Controls
Engineering measures to reduce exposure
Provide adequate ventilation.
space
Hygiene measures
Handle in accordance with good industrial hygiene and safety practice. Avoid contact with skin,
eyes and clothing. Keep away from food and drink. Wash hands before breaks and immediately
after handling the product. Contaminated work clothing should not be allowed out of the
workplace.
space
Respiratory protection
Do not inhale aerosol. No personal respiratory protective equipment normally required.
space
Hand protection
solvent-resistant gloves
space
Eye protection
safety glasses with side-shields
space
Skin and body protection
lab coat
space
Material ID 4683 Material Name 2-[125I]-Iodomelatonin
2/ 5
MSDS US
.
9. Physical & Chemical Properties
space
General Information
Form
liquid
space
Color
clear
space
.
10. Chemical Stability & Reactivity Information
space
Stability
Stable
space
Hazardous decomposition products
carbon oxides
space
Conditions to avoid
Heat, flames and sparks.
space
Incompatibility
strong oxidizing agents
space
Hazardous Polymerization
Will not occur.
.
11. Toxicological Information
space
Acute Toxicity
Methyl Alcohol may be fatal or cause blindness if swallowed.
Cannot be made non-poisonous.
Harmful by inhalation, in contact with skin and if swallowed.
Irritating to eyes, respiratory system and skin.
NIOSH - Selected LD50s and LC50s
ETHANOL 64-17-5 Inhalation LC50 Rat: 20000 ppm/10H; Inhalation
LC50 Mouse: 39 gm/m3/4H; Oral LD50 Rat: 7060
mg/kg; Oral LD50 Mouse: 3450 mg/kg
METHANOL 67-56-1 Inhalation LC50 Rat: 64000 ppm/4H; Oral LD50 Rat:
5628 mg/kg; Oral LD50 Mouse: 7300 mg/kg; Dermal
LD50 Rabbit: 15800 mg/kg
space
Carcinogenicity Data
ETHANOL
Ingredient(s)
- ACGIH Not Classified Carcinogen
space
Symptoms and Target Organs
NIOSH - Pocket Guide - Target Organs
ETHANOL 64-17-5 respiratory system, skin, eyes, CNS, liver, blood,
reproductive system
METHANOL 67-56-1 skin, eyes, CNS, GI tract, respiratory system
space
Material ID 4683 Material Name 2-[125I]-Iodomelatonin
3/ 5
MSDS US
.
12. Ecological Information
space
Ecotoxicity
Ecotoxicity - Freshwater Fish Species Data
ETHANOL 64-17-5 96 Hr LC50 rainbow trout (30 days old):12900 mg/L
(flow-through);24 Hr LC50 fingerling trout: 11200
mg/L;96 Hr LC50 fathead minnow: 14200 mg/L
(flow-through)
METHANOL 67-56-1 96 Hr LC50 fathead minnow (28 days old):29400
mg/L (flow-through);96 Hr LC50 rainbow trout
(fingerling):13 mg/L;48 Hr LC50 trout: 8000 mg/L
Ecotoxicity - Microtox Data
ETHANOL 64-17-5 5 min EC50 Photobacterium phosphoreum: 35470
mg/L; 30 min EC50 Photobacterium phosphoreum:
34634 mg/L
METHANOL 67-56-1 5 min EC50 Photobacterium phosphoreum: 43000
mg/L; 15 min EC50 Photobacterium phosphoreum:
40000 mg/L; 25 min EC50 Photobacterium
phosphoreum: 39000 mg/L
space
Aquatic Toxicity
Ecotoxicity - Freshwater Fish Species Data
ETHANOL 64-17-5 96 Hr LC50 rainbow trout (30 days old):12900 mg/L
(flow-through);24 Hr LC50 fingerling trout: 11200
mg/L;96 Hr LC50 fathead minnow: 14200 mg/L
(flow-through)
METHANOL 67-56-1 96 Hr LC50 fathead minnow (28 days old):29400
mg/L (flow-through);96 Hr LC50 rainbow trout
(fingerling):13 mg/L;48 Hr LC50 trout: 8000 mg/L
Ecotoxicity - Microtox Data
ETHANOL 64-17-5 5 min EC50 Photobacterium phosphoreum: 35470
mg/L; 30 min EC50 Photobacterium phosphoreum:
34634 mg/L
METHANOL 67-56-1 5 min EC50 Photobacterium phosphoreum: 43000
mg/L; 15 min EC50 Photobacterium phosphoreum:
40000 mg/L; 25 min EC50 Photobacterium
phosphoreum: 39000 mg/L
space
Mobility
Not available
space
Ecological Information
No data is available on the product itself.
space
.
13. Disposal Considerations
space
Disposal Instructions
In accordance with local and national regulations.
space
Waste from residues / unused products
Dispose of in accordance with local regulations
space
.
14. Transportation Information
space
US DOT
This product is not regulated for transport.
space
Material ID 4683 Material Name 2-[125I]-Iodomelatonin
4/ 5
MSDS US
.
15. Regulatory Information
space
CERCLA/SARA Section 313
2-[125I]-Iodomelatonin
Material
space
METHANOL
Ingredient(s)
space
US Federal Regulations
CERCLA/SARA - Hazardous Substances and their Reportable Quantities
METHANOL 67-56-1 5000 lb final RQ; 2270 kg final RQ
CERCLA/SARA - Section 313 - Emission Reporting
METHANOL 67-56-1 1.0 percent de minimis concentration
space
State Regulations
California - Proposition 65 - Developmental Toxicity
ETHANOL 64-17-5 developmental toxicity (when in alcoholic beverages);
initial date 10/1/87
Massachusetts - Right To Know List
ETHANOL 64-17-5 teratogen
METHANOL 67-56-1 [present]
Massachusetts - Toxics Use Reduction Act
METHANOL 67-56-1 CERCLA and 313 chemical
New Jersey - Department of Health RTK List
ETHANOL 64-17-5 sn 0844
METHANOL 67-56-1 sn 1222
Pennsylvania - RTK (Right to Know) List
ETHANOL 64-17-5 Present
METHANOL 67-56-1 environmental hazard
Rhode Island - Hazardous Substance List
ETHANOL 64-17-5 Toxic, Flammable
METHANOL 67-56-1 Toxic, Flammable; skin
space
International Regulations
Canada - WHMIS - Ingredient Disclosure
ETHANOL 64-17-5 0.1%; English Item 684; French Item 805
METHANOL 67-56-1 1%; English Item 1012; French Item 183
.
16. Other Information
space
Recommended use
For research use only.
space
Disclaimer
The information provided in this Material Safety Data Sheet is based on our present knowledge,
and believed to be correct at the date of publication. However, no representation is made
concerning its accuracy and completeness. It is intended as guidance only, and is not to be
considered a warranty or quality specification. All materials may present unknown hazards, and
should be used with caution. Although certain hazards are described, we cannot guarantee that
these are the only hazards which exist. PerkinElmer Life and Analytical Sciences shall not be held
liable for any damage resulting from handling or from contact with the product.
space
Material ID 4683 Material Name 2-[125I]-Iodomelatonin
5/ 5
MSDS US
|