**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
|----------------|--------------------------------------|----------|-----------|
|----------------|--------------------------------------|----------|-----------|
| 25493-13-4 |p-Xylene-alpha,alpha,alpha,alpha',alph| >99 | 247-033-9 |
+----------------+--------------------------------------+----------+-----------+
Text for R-phrases: see Section 16
Hazard Symbols: XN
Risk Phrases: 10 20/21 36/38
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Flammable. Harmful by inhalation and in contact with skin.
Irritating to eyes and skin.
Potential Health Effects
Eye:
Splashes of xylene in human eyes generally cause transient
superficial injury.
Skin:
May be harmful if absorbed through the skin. Xylene contact causes
defatting of the skin with irritation, dryness, and cracking.
Blistering may occur, particularly if exposure to concentrated xylene
is prolonged and the exposed area of skin is occluded.
Ingestion:
Aspiration hazard. May cause irritation of the digestive tract. May
cause central nervous system depression, characterized by
excitement, followed by headache, dizziness, drowsiness, and nausea.
Advanced stages may cause collapse, unconsciousness, coma and
possible death due to respiratory failure. Aspiration of material
into the lungs may cause chemical pneumonitis, which may be fatal.
Inhalation:
Causes respiratory tract irritation. Irritation may lead to chemical
pneumonitis and pulmonary edema. Odor thresholds ranging from 0.07 to
40 ppm have been reported for xylenes. Inhalation overexposure may
lead to central nervous system depression, producing effects such as
dizziness, headache, confusion, incoordination, nausea, weakness, and
loss of consciousness. Extreme exposures may cause other CNS effects
including death.
Chronic:
Chronic exposure to xylene may cause defatting dermatitis,
reversible eye damage, dyspnea (labored breathing), confusion,
dizziness, apprehension, memory loss, headache, tremors, weakness,
anorexia, nausea, ringing in the ears, irritability, thirst, mild
changes in liver function, kidney impairment, anemia, and
hyperplasia, but not destruction, of the bone marrow.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
In case of contact, immediately flush eyes with plenty of water for
at least 15 minutes. Get medical aid.
Skin:
In case of contact, flush skin with plenty of water. Remove
contaminated clothing and shoes. Get medical aid if irritation
develops and persists. Wash clothing before reuse.
Ingestion:
Potential for aspiration if swallowed. Get medical aid immediately.
Do not induce vomiting unless directed to do so by medical
personnel. Never give anything by mouth to an unconscious person.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Use water spray to keep fire-exposed containers
cool. Flammable liquid and vapor. Vapors may form an explosive
mixture with air. Vapors are heavier than air and may travel to a
source of ignition and flash back. Vapors can spread along the
ground and collect in low or confined areas. This liquid floats on
water and may travel to a source of ignition and spread fire. May
accumulate static electricity.
Extinguishing Media:
Water may be ineffective. This material is lighter than water and
insoluble in water. The fire could easily be spread by the use of
water in an area where the water cannot be contained. Use water
spray, dry chemical, carbon dioxide, or appropriate foam.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Remove all sources of ignition.
Use a spark-proof tool. Provide ventilation. A vapor suppressing
foam may be used to reduce vapors. Water spray may reduce vapor but
may not prevent ignition in closed spaces. U.S. regulations require
reporting spills and releases to soil, water and air in excess of
reportable quantities. This material creates a fire hazard because it
floats on water. If possible, try to contain floating material.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Ground and bond containers when transferring
material. Avoid contact with eyes, skin, and clothing. Empty
containers retain product residue, (liquid and/or vapor), and can be
dangerous. Do not pressurize, cut, weld, braze, solder, drill, grind,
or expose empty containers to heat, sparks or open flames. Use only
with adequate ventilation. Keep away from heat, sparks and flame.
Avoid breathing vapor or mist.
Storage:
Keep away from sources of ignition. Keep container closed when not
in use. Keep from contact with oxidizing materials. Store in a cool,
dry, well-ventilated area away from incompatible substances.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the
permissible exposure limits. Ventilation fans and other electrical
service must be non-sparking and have an explosion-proof design.
Exposure Limits
CAS# 106-42-3:
United Kingdom, WEL - TWA: 50 ppm TWA; 220 mg/m3 TWA
United Kingdom, WEL - STEL: 100 ppm STEL; 441 mg/m3 STEL
United States OSHA: 100 ppm TWA; 435 mg/m3 TWA (listed under Xyl
(o-, m-, p- isomers)).
Belgium - TWA: 50 ppm VLE; 221 mg/m3 VLE
Belgium - STEL: 150 ppm VLE; 442 mg/m3 VLE
France - VME: (listed as xylenes (o-, m-, p- isomers)): 100 ppm V
435 mg/m3 VME
France - VLE: (listed as xylenes (o-, m-, p- isomers)): 150 ppm V
650 mg/m3 VLE
Germany: (listed as xylenes (o-, m-, p- isomers)): 100 ppm VME; 4
mg/m3 VME
Germany: (listed as xylenes (o-, m-, p- isomers)): Skin absorber
Japan: 50 ppm OEL; 217 mg/m3 OEL
Malaysia: 199 ppm TWA; 434 mg/m3 TWA
Netherlands: (listed as xylenes (o-, m-, p- isomers)): 50 ppm MAC
210 mg/m3 MAC
Russia: (listed as xylenes (o-, m-, p- isomers)): 50 mg/m3 TWA
Spain: 50 ppm VLA-ED; 221 mg/m3 VLA-ED
Spain: 100 ppm VLA-EC; 442 mg/m3 VLA-EC
CAS# 25493-13-4:
Personal Protective Equipment
Eyes:
Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Solid or liquid
Color: clear, colorless
Odor: aromatic odor
pH: Not applicable.
Vapor Pressure: 8.84 mm Hg @ 25 deg C
Viscosity: <32.6 SUS
Boiling Point: 135.3 deg C
Freezing/Melting Point: 13 deg C
Autoignition Temperature: 528 deg C ( 982.40 deg F)
Flash Point: 27 deg C ( 80.60 deg F)
Explosion Limits, lower: 1.1%
Explosion Limits, upper: 7.0%
Decomposition Temperature: Not available.
Solubility in water: Insoluble.
Specific Gravity/Density: 0.915 (water=1)
Molecular Formula: C8H4D6
Molecular Weight: 112.22
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
High temperatures, ignition sources.
Incompatibilities with Other Materials:
Strong oxidizing agents, nitric acid.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 106-42-3: ZE2625000
CAS# 25493-13-4 unlisted.
LD50/LC50:
CAS# 106-42-3: Inhalation, rat: LC50 = 4550 ppm/4H; Oral, rat: LD50
= 3910 mg/kg.
CAS# 25493-13-4.
Carcinogenicity:
p-Xylene -
Not listed by ACGIH, IARC, or NTP.
p-Xylene-alpha,alpha,alpha,alpha',alpha',alpha'-d6 -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Fish: Rainbow trout: LC50 = 13.5 mg/L; 96 Hr; UnspecifiedFish:
Goldfish: LD50 = 13 mg/L; 24 Hr; UnspecifiedFish: Fathead Minnow:
LC50 = 46 mg/L; 1 Hr; Static bioassayAcute and long-term toxicity to
fish and invertebrates: LD50 for goldfish is 13 mg/L/24
Hr.
Cas#1330-20-7:
LC50(96Hr.) rainbow trout = 8.05 mg/L, Static
condition;
LC50(96Hr.) fathead minnow = 16.1 mg/L, flow-through
conditions; LC50(96Hr.) bluegill = 16.1 mg/L, flow-through;
EC50 (48
Hr.) water flea = 3.82 mg/L, flow-through conditions;
EC50(24 Hr.)
photobacterium phosphoreum = 0.0084 mg/L, Microtox test.
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: XYLENES
Hazard Class: 3
UN Number: 1307
Packing Group: III
IMO
Shipping Name: XYLENES
Hazard Class: 3.3
UN Number: 1307
Packing Group: III
RID/ADR
Shipping Name: XYLENES
Hazard Class: 3
UN Number: 1307
Packing group: III
USA RQ: CAS# 106-42-3: 100 lb final RQ (Listed under Xylene, mixed); 45.4 kg fin
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 10 Flammable.
R 20/21 Harmful by inhalation and in contact with
skin.
R 36/38 Irritating to eyes and skin.
Safety Phrases:
S 25 Avoid contact with eyes.
WGK (Water Danger/Protection)
CAS# 106-42-3: 2
CAS# 25493-13-4: No information available.
Canada
CAS# 106-42-3 is listed on Canada's DSL List.
CAS# 106-42-3 is listed on Canada's Ingredient Disclosure List.
CAS# 25493-13-4 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 106-42-3 is listed on the TSCA inventory.
CAS# 25493-13-4 is not listed on the TSCA inventory.
It is for research and development use only.
**** SECTION 16 - ADDITIONAL INFORMATION ****
Text for R-phrases from Section 2
MSDS Creation Date: 6/17/1999 Revision #8 Date: 3/05/2004
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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