**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 506-68-3 |Cyanogen Bromide | 97-100 | 208-051-2 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: T+
Risk Phrases: 26/27/28 34
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Very toxic by inhalation, in contact with skin and if swallowed.
Causes burns.Corrosive.Moisture sensitive.Air sensitive.Light
sensitive.
Potential Health Effects
Eye:
Causes eye burns. Lachrymator (substance which increases the flow
of tears). Causes redness and pain.
Skin:
May be fatal if absorbed through the skin. Causes skin burns. If
absorbed, may cause symptoms similar to those for ingestion. May be
metabolized to cyanide which in turn acts by inhibiting cytochrome
oxidase impairing cellular respiration. Substance is readily
absorbed through the skin.
Ingestion:
May be fatal if swallowed. May cause severe gastrointestinal tract
irritation with nausea, vomiting and possible burns. May cause
central nervous system effects. Metabolism may release cyanide,
which may result in headache, dizziness, weakness, collapse,
unconsciousness and possible death. Ingestion may result in symptoms
similar to cyanide poisoning which is characterized by asphyxiation.
Inhalation:
May cause cyanosis (bluish discoloration of skin due to deficient
oxygenation of the blood). Causes chemical burns to the respiratory
tract. Inhalation may be fatal as a result of spasm, inflammation,
edema of the larynx and bronchi, chemical pneumonitis and pulmonary
edema. May cause nausea, dizziness, and headache. May produce
cardiovascular effects. May be metabolized to cyanide which in turns
act by inhibiting cytochrome oxidase impairing cellular respiration.
Inhalation may result in symptoms similar to cyanide poisoning which
include tachypnea, hyperpnea (abnormally rapid or deep breathing),
and dyspnea (labored breathing) followed rapidly by respiratory
depression. Pulmonary edema may occur.
Chronic:
Chronic exposure to cyanide solutions may lead to the development of
a "cyanide" rash, characterized by itching, and by macular, papular,
and vesicular eruptions, and may be accompanied by secondary
infections. Exposure to small amounts of cyanide compounds over long
periods of time is reported to cause loss of appetite, headache,
weakness, nausea, dizziness, and symptoms of irritation of the upper
respiratory tract and eyes.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Get medical aid immediately. Do NOT allow victim to rub eyes or keep
eyes closed. Extensive irrigation with water is required (at least 30
minutes).
Skin:
Get medical aid immediately. Immediately flush skin with plenty of
water for at least 15 minutes while removing contaminated clothing
and shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4
cupfuls of milk or water. Never give anything by mouth to an
unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If breathing is difficult, give oxygen. Do NOT use
mouth-to-mouth resuscitation. If breathing has ceased apply
artificial respiration using oxygen and a suitable mechanical device
such as a bag and a mask. SPEED IS ESSENTIAL, OBTAIN MEDICAL AID
IMMEDIATELY.
Notes to Physician:
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. Will react
with water to form toxic and corrosive fumes. This chemical poses an
explosion hazard. Reaction with water may generate much heat which
will increase the concentration of fumes in the air. Contact with
metals may evolve flammable hydrogen gas. Containers may explode
when heated or if contaminated with water.
Extinguishing Media:
Use carbon dioxide or dry chemical. Do NOT get water inside
containers. Most foams will react with the material and release
corrosive/toxic gases. DO NOT USE WATER OR FOAM.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Clean up spills immediately, observing precautions in the
Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation. Do not get water inside containers.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Minimize dust generation and accumulation. Do not
get in eyes, on skin, or on clothing. Do not ingest or inhale. Do
not allow contact with water. Use only in a chemical fume hood. Keep
from contact with moist air and steam.
Storage:
Do not store in direct sunlight. Store in a tightly closed
container. Keep refrigerated. (Store below 4C/39F.) Keep away from
acids. Store protected from moisture.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the
permissible exposure limits.
Exposure Limits
CAS# 506-68-3:
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Crystals
Color: white
Odor: penetrating odor
pH: Not available.
Vapor Pressure: 100 mm Hg @ 22 C
Viscosity: Not available.
Boiling Point: 61-62 deg C
Freezing/Melting Point: 49-54 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: Reacts with water.
Specific Gravity/Density: 2.015g/cm3
Molecular Formula: CBrN
Molecular Weight: 105.9107
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Polymerization at low temperatures may occur. Reacts with water to
form toxic fumes. Unstable. May react with carbon dioxide in the air
to form toxic hydrogen cyanide.
Conditions to Avoid:
Light, dust generation, excess heat, exposure to moist air or water,
prolonged exposure to air.
Incompatibilities with Other Materials:
Moisture, oxidizing agents, metals, alcohols, ammonia, amines, acids.
Hazardous Decomposition Products:
Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide,
hydrogen bromide.
Hazardous Polymerization: May occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 506-68-3: GT2100000
LD50/LC50:
Not available.
Carcinogenicity:
Cyanogen Bromide -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: CYANOGEN BROMIDE
Hazard Class: 6.1 (8)
UN Number: 1889
Packing Group:
IMO
Shipping Name: CYANOGEN BROMIDE
Hazard Class: 6.1 (8)
UN Number: 1889
Packing Group: I
RID/ADR
Shipping Name: CYANOGEN BROMIDE
Hazard Class: 6.1 (8)
UN Number: 1889
Packing group: I
USA RQ: CAS# 506-68-3: 1000 lb final RQ; 454 kg final RQ
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T+
Risk Phrases:
R 26/27/28 Very toxic by inhalation, in contact with
skin and if swallowed.
R 34 Causes burns.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 28A After contact with skin, wash immediately with
plenty of water.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 506-68-3: 3
Canada
CAS# 506-68-3 is listed on Canada's DSL List.
CAS# 506-68-3 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 506-68-3 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 6/02/1998 Revision #4 Date: 4/15/2005
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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